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PRI-724

CBP/beta-catenin antagonist

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Catalog No. A15856

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
PRI-724 10mg A15856-10
$100.00
PRI-724 25mg A15856-25
$200.00
PRI-724 50mg A15856-50
$350.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

PRI-724, an isomer or enantiomer of ICG-001 (A11039), is a potent, specific inhibitor of the canonical Wnt signaling pathway in cancer stem cells with potential antineoplastic activity.

PRI-724

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Chemical Information

Catalog Num A15856
Actions Antagonist
M. Wt 548.24
Formula C33H32N4O4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 847591-62-2
Synonyms PRI 724, PRI724
SMILES O=C(N(CC1)[[email protected]](CN(CC2=C3C=CC=CC3=CC=C2)C([[email protected]@H]4CC5=CC=C(O)C=C5)=O)([H])N4C1=O)NCC6=CC=CC=C6

Biological Activity

Description

PRI-724, an isomer or enantiomer of ICG-001 (A11039), is a potent, specific inhibitor of the canonical Wnt signaling pathway in cancer stem cells with potential antineoplastic activity.

Targets
Wnt/β-catenin
150 nM

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.24 mL 91.2 mL 182.4mL
0.5 mM 3.65 mL 18.24 mL 36.48 mL
1 mM 1.82 mL 9.12 mL 18.24 mL
5 mM 0.36 mL 1.82 mL 3.65 mL

*The above data is based on the productmolecular weight 548.24. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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