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- Baharak Bahmani, .et al. Intratumoral immunotherapy using platelet-cloaked nanoparticles enhances antitumor immunity in solid tumors, Nat Commun, 2021, Mar 31;12(1):1999 PMID: 33790276
Biological Activity
Prostaglandin E1 (PGE1) is the theoretical cyclooxygenase metabolite of dihomo-γ-linolenic acid (DGLA), but it is virtually undetectable in the plasma of normal humans or other animals. The IC50 of PGE1 for the inhibition of ADP-induced human platelet aggregation is 40 nM.
Targets
| In vitro | DMSO | 66 mg/mL (186.19 mM) | |
| Water | Insoluble | ||
| Ethanol | 66 mg/mL (186.19 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 28.21 mL | 141.05 mL | 282.1 mL |
| 0.5 mM | 5.64 mL | 28.21 mL | 56.42 mL |
| 1 mM | 2.82 mL | 14.11 mL | 28.21 mL |
| 5 mM | 0.56 mL | 2.82 mL | 5.64 mL |
*The above data is based on the productmolecular weight 354.48. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A11820 |
|---|---|
| CAS No. | 745-65-3 |
| Formula | C20H34O5 |
| M. Wt | 354.48 |
| Purity | >98% |
| Synonyms | PGE1 |
| SMILES | CCCCC[[email protected]@H](/C=C/[[email protected]]1[[email protected]@H](CC(=O)[[email protected]@H]1CCCCCCC(=O)O)O)O |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
Datasheet
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