Proteases - Akt3

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  1. SHIP-2 inhibitor

    AS1949490 is a potent and selective SHIP-2 (SH2 domain-containing inositol 5?? phosphatase 2) inhibitor, with an IC50 of 620 nM. AS1949490 activated glucose metabolism via up-regulation of GLUT1 gene in L6 myotubes.

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