AS194949

Catalog No.: A20847

SHIP-2 inhibitor

AS194949

AS194949 Chemical Structure

CAS NO. 1203680-76-5

AS1949490 is a potent and selective SHIP-2 (SH2 domain-containing inositol 5?? phosphatase 2) inhibitor, with an IC50 of 620 nM. AS1949490 activated glucose metabolism via up-regulation of GLUT1 gene in L6 myotubes.

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5 mg

Regular Price: $144.00

Special Price $115.20

10 mg

Regular Price: $248.00

Special Price $198.40

50 mg

Regular Price: $736.00

Special Price $588.80

100 mg

Regular Price: $1,472.00

Special Price $1,177.60

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Biological Activity

AS1949490 is a potent and selective SHIP-2 (SH2 domain-containing inositol 5?? phosphatase 2) inhibitor, with an IC50 of 620 nM. AS1949490 activated glucose metabolism via up-regulation of GLUT1 gene in L6 myotubes.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.89 mL 134.45 mL 268.9 mL
0.5 mM 5.38 mL 26.89 mL 53.78 mL
1 mM 2.69 mL 13.45 mL 26.89 mL
5 mM 0.54 mL 2.69 mL 5.38 mL

*The above data is based on the productmolecular weight 371.88. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A20847
Actions Inhibitor
CAS No. 1203680-76-5
Formula C20H18ClNO2S
M. Wt 371.88
Purity >98%
Synonyms AS 194949, AS-194949
SMILES O=C(C1=C(OCC2=CC=C(Cl)C=C2)C=CS1)N[[email protected]](C3=CC=CC=C3)C
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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