Catalog No.
Product Name
Application
Product Information
Citations
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PROTAC Linker
Mal-amido-PEG2-TFP ester is a polyethylene glycol (PEG) derivative designed as a linker for PROTAC (Proteolysis Targeting Chimeras) synthesis. This compound facilitates the conjugation of ligands to E3 ubiquitin ligases, enhancing the targeted degradation of specific proteins within cellular contexts. Its application is essential in the development of novel therapeutic agents aimed at mitigating diseases by promoting the selective proteolysis of target proteins. -
PROTAC Linker
1-(1,1-Dimethylethyl) tridecanedioate serves as a versatile PROTAC linker, facilitating the synthesis of heterobifunctional molecules for targeted protein degradation. Its structure contributes to the development of PROTACs by enhancing stability and solubility, thereby improving cellular uptake and efficacy. This compound is valuable for researchers exploring targeted therapeutics and protein modulation strategies in various biological systems. -
PROTAC Linker
N-Boc-N-bis(PEG4-acid) is a PEG-based linker designed for use in the synthesis of PROTACs (proteolysis-targeting chimeras). This compound facilitates the construction of bifunctional molecules that recruit E3 ubiquitin ligases for targeted protein degradation. Its hydrophilic nature enhances solubility and bioavailability, making it suitable for various biochemical and pharmacological applications in chemical biology research. -
PROTAC Linker
Amino-PEG7-t-butyl ester is a PEG-based linker designed for PROTAC (Proteolysis Targeting Chimera) synthesis. Featuring an amino (NH2) group and a tert-butyl protected carboxyl moiety, this reagent facilitates the construction of PROTAC molecules that enhance targeted protein degradation. Its applications extend to drug delivery research, making it a valuable tool for developing novel therapeutic strategies. -
PROTAC Linker
Methyl 6-hydroxyhexanoate is a versatile PROTAC linker utilized in the synthesis of proteolysis-targeting chimeras (PROTACs). Its structure facilitates the selective degradation of target proteins through recruitment of E3 ligases, enabling advanced studies in targeted protein modulation. This compound plays a crucial role in drug discovery and development, particularly in the exploration of novel therapeutic strategies for various diseases. -
PROTAC Linker
Tridecane-1,13-diol is a versatile PROTAC linker utilized in the synthesis of proteolysis targeting chimeras (PROTACs). This compound features a 13-carbon hydrocarbon backbone with hydroxyl groups at both ends, facilitating efficient conjugation of target proteins to E3 ligases. Its application in PROTAC development supports targeted degradation of proteins, enhancing research in protein modulation and therapeutic interventions in diseases driven by aberrant protein expression. -
PROTAC Linker
Benzyl (3-bromopropyl)carbamate serves as a PROTAC linker, facilitating the construction of proteolysis-targeting chimeras (PROTACs). This compound is essential for the development of novel therapeutic agents that induce selective degradation of target proteins through the ubiquitin-proteasome system. Its precise composition and structure enable effective conjugation with target proteins and E3 ligases, enhancing the potential for targeted protein modulation in various biological research applications. -
PROTAC Linker
trans-4-Cyanocyclohexane-1-carboxylic acid serves as a versatile linker in the synthesis of PROTACs (proteolysis-targeting chimeras). This compound facilitates the conjugation of target proteins to E3 ligases, enabling targeted protein degradation. Its unique structure enhances hydrophilicity and may improve cellular permeability, making it suitable for various applications in drug discovery and the study of protein function and regulation. -
PROTAC Linker
tert-Butyl 4-cyanopiperazine-1-carboxylate is a PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates targeted protein degradation through the recruitment of E3 ubiquitin ligases, thereby enabling the selective modulation of protein levels. Its unique structure offers versatility in designing novel PROTACs for various therapeutic applications in cellular and molecular biology research. -
PROTAC Linker
(9H-Fluoren-9-yl)methyl (4-aminobutyl)carbamate hydrochloride is a versatile PROTAC linker that facilitates the synthesis of proteolysis-targeting chimeras (PROTACs). This compound enhances the stability and efficacy of PROTACs by enabling targeted protein degradation. Its chemical structure supports various biological applications in drug discovery and molecular biology, particularly in the development of novel therapeutic strategies. -
PROTAC Linker
Benzyl (2-(2-aminoethoxy)ethyl)carbamate is a PROTAC linker designed to facilitate the development of proteolysis-targeting chimeras (PROTACs). This compound serves as a crucial component in the synthesis of PROTACs, enabling researchers to efficiently target specific proteins for degradation. Its application in chemical biology allows for the exploration of targeted protein modulation and novel therapeutic strategies. -
PROTAC Linker
tert-Butyl (8-hydroxyoctyl)carbamate is a versatile PROTAC linker utilized in the design and synthesis of PROTAC molecules. It facilitates the recruitment of E3 ligases and the targeted degradation of specific proteins, making it valuable for studies in targeted protein degradation and therapeutic development. Its unique structure enhances the efficiency and selectivity of PROTAC applications in chemical biology research. -
PROTAC Linker
N-Boc-Piperidin-4-yl-acetic acid methyl ester serves as a PROTAC linker that plays a crucial role in the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the recruitment of E3 ubiquitin ligases to target proteins for ubiquitination and subsequent degradation. Its unique structure enables effective linkages that enhance target specificity and efficacy in cellular environments. Researchers utilize this reagent to develop innovative therapeutic strategies for the selective modulation of protein levels in biological systems. -
PROTAC Linker
Dde Biotin-PEG4-azide is a PEG-based linker designed for the synthesis of PROTACs, functioning primarily through click chemistry. This reagent features an azide group that participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. Additionally, it can facilitate strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN-modified compounds. Its applications are particularly valuable in chemical biology for targeted protein degradation studies and related research endeavors. -
PROTAC Linker
tert-Butyl N-[2-(aminooxy)ethyl]carbamate is utilized as a PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This reagent enhances the design of bifunctional molecules that can selectively degrade specific proteins within cellular pathways. Its versatility in linking ligands and E3 ubiquitin ligases makes it valuable in various research applications, including targeted protein degradation studies and drug discovery efforts. -
PROTAC Linker
tert-Butyl N-methyl-N-(piperidin-4-ylmethyl)carbamate serves as a versatile PROTAC linker for the development of Proteolysis Targeting Chimeras (PROTACs). This compound facilitates the selective degradation of target proteins by connecting an E3 ligase recruiter with a target protein binder. It is instrumental in research focused on targeted protein degradation, enabling the exploration of novel therapeutic strategies in various disease contexts. -
PROTAC Linker
6-Bromohexan-1-amine hydrobromide is a synthetic linker specifically designed for use in PROTAC (Proteolysis Targeting Chimera) technology. This compound facilitates the creation of bifunctional molecules that induce targeted protein degradation, allowing for the selective modulation of protein levels in cell signaling pathways. Its applications extend to cancer research, drug discovery, and the development of novel therapeutic strategies by enabling precise control over protein interactions and degradation. -
PROTAC Linker
1-(2-Aminoethyl)piperidin-4-ol is a versatile PROTAC linker that facilitates the development of targeted protein degradation strategies. It enhances the stability and efficacy of PROTACs by connecting target proteins to E3 ligases, thereby promoting ubiquitination and subsequent degradation. This reagent is essential for researchers exploring protein regulation and therapeutic applications in cancer and other diseases. -
PROTAC Linker
Tert-Butyl 6-amino-2-azaspiro[3.4]octane-2-carboxylate serves as a versatile PROTAC linker, facilitating the development of targeted protein degradation strategies. This compound enhances the synthesis of PROTACs by providing a stable connection between target proteins and E3 ligases. Its structural features support the efficient formation of bifunctional molecules, making it an essential tool for researchers investigating targeted degradation pathways in cellular processes and disease models. -
PROTAC Linker
CbzNH-PEG3-OH is a PROTAC linker designed to facilitate the development of proteolysis-targeting chimeras (PROTACs). This compound enhances the stability and solubility of PROTACs, promoting effective protein degradation in various cellular contexts. It is utilized in research applications focused on targeted protein degradation, providing a valuable tool for studying protein function and developing therapeutic strategies. -
PROTAC Linker
Benzyl 3-(hydroxymethyl)azetidine-1-carboxylate functions as a versatile PROTAC linker, facilitating the design and synthesis of proteolysis-targeting chimera (PROTAC) molecules. Its structural attributes enhance the efficiency of targeted protein degradation, making it a valuable tool in drug discovery and development. This compound is particularly useful in research focused on targeted therapies and mechanistic studies involving protein regulation. -
PROTAC Linker
4-(tert-Butyldimethylsilyloxy)-1-butyne serves as a versatile PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound enhances the selective degradation of target proteins by linking E3 ligases and protein targets. Its applications are significant in the fields of drug discovery and molecular biology, particularly for studies focused on targeted protein degradation and therapeutic intervention. -
PROTAC Linker
tert-Butyl (4-hydroxycyclohexyl)carbamate functions as a PROTAC linker, facilitating the design and synthesis of targeted protein degradation agents. This compound is essential for creating bifunctional molecules that recruit specific E3 ligases to target proteins for degradation. Its use is pivotal in research applications focused on studying protein function and developing therapeutic strategies for diseases involving dysregulated protein levels. -
PROTAC Linker
TBS-PEG2-OH is a polymeric linker designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). This compound facilitates the conjugation of the target protein and an E3 ligase through a polyethylene glycol (PEG) backbone, enhancing the stability and solubility of the PROTAC. It is valuable in drug development research focused on targeted protein degradation and novel therapeutic strategies. -
PROTAC Linker
3-(4-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)phenyl)propanoic acid serves as a PROTAC linker, facilitating the creation of proteolysis-targeting chimeras (PROTACs). This compound enables the selective degradation of target proteins by promoting the recruitment of E3 ligases. Its application is pivotal in the development of novel therapeutics aimed at addressing various diseases by modulating protein levels within biological systems. -
PROTAC Linkers
Fmoc-NH-PEG4-alcohol is a polyethylene glycol (PEG) based linker specifically designed for the synthesis of PROTACs (proteolysis-targeting chimeras). This compound serves as a versatile scaffold, facilitating the construction of bifunctional molecules that can selectively induce the degradation of target proteins. Its unique chemical properties support various research applications in targeted protein degradation and therapeutic development. -
PROTAC Linkers
m-PEG10-CH2COOH is a polyethylene glycol (PEG) linker designed for use in the synthesis of PROTAC (proteolysis-targeting chimera) molecules. This compound facilitates the conjugation of ligands to target proteins, enhancing the efficiency of protein degradation pathways. Its application in PROTAC development supports research in targeted protein modulation and therapeutic intervention in various diseases. -
PROTAC Linker
{3-[(tert-Butyldimethylsilyl)oxy]cyclobutyl}methanol serves as a PROTAC linker, designed for use in the synthesis of proteolysis-targeting chimeras (PROTACs). This molecule facilitates the recruitment of E3 ubiquitin ligases, thereby enabling targeted protein degradation. Its unique structure enhances solubility and stability, making it a valuable tool in chemical biology and therapeutic development research. -
PROTAC Linker
Cbz-NH-PEG12-C2-acid is a PEG-based linker designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). It facilitates the formation of targeted protein degraders by linking an E3 ligase ligand to a protein target, thus enabling selective degradation of specific intracellular proteins. This reagent is essential for researchers investigating targeted protein degradation mechanisms and developing novel therapeutic strategies in the fields of cancer and other diseases. -
PROTAC Linker
4-Bromophenylacetonitrile is a PROTAC linker utilized in the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates targeted protein degradation, enabling researchers to manipulate cellular protein levels and investigate biological pathways. Its application is pivotal in drug discovery and development, particularly for therapeutic interventions aimed at degrading specific proteins within various cellular environments. -
PROTAC Linker
2-{2-[(tert-Butoxy)carbonyl]-2-azaspiro[3.3]heptan-6-yl}acetic acid is a PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the targeted degradation of specific proteins by linking E3 ligases with the desired substrates, thereby enabling the modulation of cellular processes. Its application in research provides valuable insights into protein function and regulation, making it a vital tool for drug discovery and development. -
PROTAC Linker
tert-Butyl 4-(2-ethoxy-2-oxoethyl)piperidine-1-carboxylate functions as a PROTAC linker, playing a critical role in the development of proteolysis-targeting chimeras (PROTACs). This compound facilitates the selective degradation of target proteins, thereby aiding in investigations of protein function and biological pathways. Its use in PROTAC synthesis enables researchers to explore targeted therapeutics for various diseases, including cancer and neurodegenerative disorders. -
PROTAC Linker
3-((tert-Butoxycarbonyl)amino)propyl 4-methylbenzenesulfonate is a versatile PROTAC linker designed for the synthesis of PROTAC molecules. Its structure facilitates the recruitment of E3 ligases, enhancing protein degradation through the ubiquitin-proteasome pathway. This reagent is essential for researchers focused on targeted protein degradation and therapeutic development in cancer and other diseases. -
PROTAC Linker
18-((2,5-Dioxopyrrolidin-1-yl)oxy)-18-oxooctadecanoic acid is a specialized linker designed for the synthesis of Proteolysis Targeting Chimeras (PROTACs). This compound facilitates the effective conjugation of target proteins to E3 ligases, promoting selective degradation pathways. Its application extends to chemical biology research, particularly in the development of targeted protein degradation strategies. -
PROTAC Linker
Heptadecanedioic acid is a PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the selective degradation of target proteins, providing researchers with a powerful tool for studying protein function and regulation. Its unique structure enhances the efficiency of PROTAC development in various cellular contexts, making it valuable for drug discovery and therapeutic applications. -
PROTAC Linker
Cyclohexane-1,4-diyldimethanamine functions as a PROTAC linker, facilitating the synthesis of bifunctional small molecules that induce targeted protein degradation. Its structural attributes enhance the stability and efficacy of PROTAC compounds, making it valuable in drug discovery and development. This linker is essential for studies aimed at elucidating protein function and therapeutic intervention strategies in various diseases. -
PROTAC Linker
6-Bromohex-1-yne is a versatile PROTAC linker designed for the synthesis of targeted protein degraders. Its unique structure facilitates the formation of linkages between E3 ligase recruiters and target proteins, enabling effective modulation of protein levels within cells. This compound is essential for researchers aiming to explore targeted protein degradation mechanisms in various biological pathways. -
PROTAC Linker
3-Boc-3,9-Diazaspiro[5.5]undecane hydrochloride serves as an innovative PROTAC linker, facilitating the formation of proteolysis-targeting chimeras (PROTACs). This compound is crucial for advancing research in targeted protein degradation by providing a robust connecting moiety in PROTAC synthesis. Its unique structural properties enhance the efficacy of bifunctional molecules, making it valuable for studying protein interactions and degradation pathways in various biological contexts. -
PROTAC Linker
2-(3-Chloropropyl)-1,3-dioxolane serves as a PROTAC linker, facilitating the construction of proteolysis-targeting chimeras (PROTACs). This compound is crucial for the development of targeted protein degradation strategies, allowing researchers to create bifunctional molecules that recruit E3 ligases to specific target proteins. Its application enhances the study of protein regulation and modulation in various biological contexts. -
PROTAC Linker
3,3'-Oxybis(propan-1-ol) is a versatile PROTAC linker utilized in the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the conjugation of target proteins to E3 ligases, enabling targeted degradation pathways in cellular models. Its application is critical in the development of advanced therapeutic strategies for various diseases, particularly in the realm of cancer research. -
PROTAC Linker
tert-Butyl 3-(methylamino)propanoate serves as a versatile PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs) for targeted protein degradation. This compound enables the effective conjugation of target proteins with E3 ligases, enhancing the specificity and efficacy of PROTACs in biochemical research. Its application is crucial in investigations focused on protein modulation and therapeutic development within the context of cancer and other diseases. -
PROTAC Linker
(9H-Fluoren-9-yl)methyl (5-hydroxypentyl)carbamate serves as a PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound is instrumental in connecting E3 ligase recruitment and target proteins, enabling targeted protein degradation. Its application is pivotal in chemical biology studies focusing on protein regulation and therapeutic intervention. -
PROTAC Linker
10-Bromodecanoic acid serves as a versatile linker in the synthesis of PROTACs, particularly in the development of targeted protein degraders. This reagent facilitates the construction of PROTAC molecules, such as the PROTAC KDM4 degrader-1, enabling specific degradation of target proteins through the ubiquitin-proteasome pathway. Its unique structure allows for enhanced stability and solubility, making it suitable for various biochemical applications in drug discovery and development. -
PROTAC Linker
1-Cbz-Azetidine-3-CH2NH2 is a versatile PROTAC linker that facilitates the construction of proteolysis-targeting chimeras (PROTACs). Its unique structural features allow for effective engagement of target proteins for ubiquitination and subsequent degradation. This compound is ideal for research applications involving targeted protein degradation and molecular biology studies focused on modulating protein levels within cellular systems. -
PROTAC Linker
tert-Butyl 3-cyanoazetidine-1-carboxylate is a PROTAC linker designed for the creation of proteolysis-targeting chimeras (PROTACs). Its unique structure facilitates the recruitment of E3 ligases, enhancing targeted protein degradation. This compound is essential in the development of novel therapeutic modalities aimed at selectively modulating protein levels within cells, making it valuable in both academic and pharmaceutical research settings. -
PROTAC Linker
cis-1-(tert-Butoxycarbonyl)-3-fluoropiperidine-4-carboxylic acid serves as a PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound enhances the selectivity and efficacy of targeted protein degradation by linking E3 ligases with specific target proteins. It is suitable for research applications focused on targeted protein modulation and therapeutic development in cancer and other diseases. -
PROTAC Linker
tert-Butyl 4-(4-bromophenyl)piperidine-1-carboxylate acts as a PROTAC linker essential for the design and synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the formation of targeted protein degraders, enhancing the specificity and efficacy of therapeutic interventions in various biological contexts. Its structural properties make it an invaluable tool in drug discovery and development aimed at modulating protein function. -
PROTAC Linker
4-((tert-Butoxycarbonyl)amino)cyclohexanecarboxylic acid serves as a versatile PROTAC linker, facilitating the construction of proteolysis-targeting chimeras (PROTACs). This compound enables controlled degradation of target proteins, thereby aiding research into therapeutic interventions and cellular regulation mechanisms. Its application is vital in drug discovery and development strategies aimed at tackling diseases through targeted protein modulation. -
PROTAC Linker
1,4-Cyclohexanedimethanol serves as an essential PROTAC linker, facilitating the design and synthesis of proteolysis-targeting chimeras (PROTACs). Its structural attributes allow for effective conjugation of target proteins to E3 ligases, enhancing the development of novel therapeutic strategies for targeted protein degradation. This compound is suitable for various applications in chemical biology and drug discovery research. -
PROTAC Linker
tert-Butyl 17-bromoheptadecanoate is a versatile PROTAC linker utilized in the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the development of targeted protein degradation strategies, enhancing the specificity and efficacy of therapeutic interventions. Its unique structure allows for the effective conjugation of target proteins and ligands, making it a valuable reagent in chemical biology and drug discovery research.
