Catalog No.
Product Name
Application
Product Information
Citations
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PROTAC Linker
3-(4-((1-(Tert-butoxycarbonyl)piperidin-4-yl)oxy)phenyl)propanoic acid is a versatile PROTAC linker designed for the formation of proteolysis-targeting chimeras (PROTACs). This compound facilitates the targeted degradation of specific proteins by linking an E3 ligase ligand to a protein of interest, enabling selective modulation of protein levels within cellular systems. It is essential for researchers focusing on targeted protein degradation and therapeutic discovery in various biological pathways. -
PROTAC Linker
Ethyl 1-(2-ethoxy-2-oxoethyl)piperidine-4-carboxylate functions as a PROTAC linker, facilitating the effective design and synthesis of proteolysis-targeting chimeras (PROTACs). This compound enables the selective degradation of target proteins through the hijacking of the ubiquitin-proteasome system. Its application is critical in the development of innovative therapeutic strategies in chemical biology and drug discovery. -
PROTAC Linker
N,N'-Dimethyl-1,3-propylenediamine is a PROTAC linker that serves as a crucial component in the development of proteolysis-targeting chimeras (PROTACs). It facilitates the conjugation of target proteins to E3 ligases, promoting ubiquitination and subsequent proteasomal degradation. This compound is essential for research in targeted protein degradation and therapeutic discovery, enabling precise modulation of protein activity in various biological contexts. -
PROTAC Linker
tert-Butyl (4-aminobut-2-en-1-yl)carbamate hydrochloride serves as a versatile PROTAC linker, facilitating the synthesis of proteolysis-targeting chimeras (PROTACs). Its structural features enable efficient conjugation to target proteins, enhancing selective degradation processes in cellular systems. This compound is invaluable for research applications focusing on targeted protein degradation, contributing to advancements in therapeutic strategies against various diseases. -
PROTAC Linker
5-Chloropentyl acetate is a chemical compound designed as a PROTAC linker for targeted protein degradation applications. Its structural properties facilitate the synthesis of PROTACs, enabling the selective modulation of protein levels within cells. This compound serves as a vital tool for researchers exploring advanced therapeutic strategies in fields such as cancer biology and drug discovery. -
PROTAC Linker
(2S,3S)-Dimethyl 2,3-dihydroxysuccinate functions as a crucial PROTAC linker, facilitating the synthesis of proteolysis-targeting chimeras (PROTACs). This compound enhances the selective degradation of target proteins, contributing to targeted therapy research. Its structural properties are valuable in the development of innovative approaches for modulating protein levels in various biological contexts. -
PROTAC Linker
Bis(2,5-dioxopyrrolidin-1-yl) heptanedioate serves as a PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound plays a crucial role in connecting target protein ligands with E3 ligase recruitment elements, thereby enabling targeted protein degradation. It is an essential tool for researchers investigating protein regulation and degradation pathways in various biological contexts. -
PROTAC Linker
DBCO-PEG4-acid is a polyethylene glycol (PEG)-based linker designed for proteolysis-targeting chimeras (PROTACs). This compound effectively facilitates the development of PROTACs by allowing for the conjugation of ligands, enhancing target specificity and degradation efficiency. It is ideal for research applications focusing on targeted protein degradation and the modulation of protein levels in cellular assays. -
PROTAC Linker
(3-Aminocyclobutyl)methanol hydrochloride serves as a key PROTAC linker in the synthesis of PROTACs (Proteolysis Targeting Chimeras). This compound facilitates the targeted degradation of specific proteins by joining a target protein ligand with an E3 ubiquitin ligase ligand, thereby enabling therapeutic applications in cellular studies and drug discovery. Its unique structural properties make it valuable for research focused on protein modulation and degradation mechanisms. -
PROTAC Linker
tert-Butyl 8-amino-2-azaspiro[4.5]decane-2-carboxylate serves as a key PROTAC linker, enabling the targeted degradation of specific proteins within cells. This compound is essential for the synthesis of PROTACs, which leverage the ubiquitin-proteasome system for selective protein degradation. Its unique structural characteristics facilitate the development of innovative therapeutic strategies in drug discovery and development. -
PROTAC Linker
Cis-3-Aminocyclobutanecarbonitrile hydrochloride is a versatile PROTAC linker that facilitates the development of proteolysis-targeting chimeras (PROTACs). With its unique structural properties, it enables targeted degradation of specific proteins, thereby contributing to the regulation of various biological pathways. This compound is essential for researchers exploring targeted protein degradation and its applications in therapeutic development. -
PROTAC Linker
3-(3-Oxocyclobutyl)propanoic acid serves as a versatile PROTAC linker, facilitating the design and synthesis of Proteolysis Targeting Chimeras (PROTACs). This compound enhances the engagement of E3 ligases and target proteins, contributing to the effective degradation of specific proteins within cellular contexts. Its application in research significantly aids in the development of targeted protein degradation strategies for therapeutic and biochemical studies. -
PROTAC Linker
Tert-butyl 7-(prop-2-yn-1-yl)-2,7-diazaspiro[3.5]Nonane-2-carboxylate is a specialized PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). It facilitates the selective degradation of specific proteins by bridging them with E3 ubiquitin ligases. This compound is essential for applications in targeted protein degradation research and helps in the development of novel therapeutic strategies. -
PROTAC Linker
PEG3-bis(chloro) is a PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the conjugation of E3 ligases to target proteins, enabling selective degradation and modulation of protein function. Its applications are critical in drug discovery and the study of protein dynamics in various biological systems. -
PROTAC Linker
Ethyl 4-(piperazin-1-yl)benzoate serves as a key linker in the synthesis of PROTAC (Proteolysis Targeting Chimeras) molecules. This compound facilitates the assembly of target proteins for ubiquitin-mediated degradation, thereby enabling the study of protein function and regulation. Its application in drug discovery and development makes it a valuable tool for researchers focusing on targeted protein degradation strategies. -
PROTAC Linker
N,N-Di-(beta-carboethoxyethyl)methylamine is a versatile PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the recruitment of E3 ligases to targeted proteins, thereby enabling selective degradation of disease-associated proteins. Its application is particularly relevant in targeted protein degradation studies, offering potential insights into protein function and therapeutic interventions. -
PROTAC Linker
(4-Bromobutoxy)benzene serves as a PROTAC linker, facilitating the development of targeted protein degradation technologies. This compound enables researchers to effectively harness the ubiquitin-proteasome system for the selective degradation of intracellular proteins. Its structural attributes support the assembly of bifunctional molecules essential for the advancement of therapeutic applications in drug discovery. -
PROTAC Linker
Methyl 6-chloro-6-oxohexanoate serves as a PROTAC linker, facilitating the synthesis of protein-targeting chimeras known as proteolysis-targeting chimeras (PROTACs). This compound enables the selective degradation of target proteins via the ubiquitin-proteasome pathway, making it an essential tool in drug discovery and development. Its role in the design of novel therapeutics holds significant promise for advancing research in targeted protein modulation and therapeutic intervention. -
PROTAC Linker
tert-Butyl 2-cyano-7-azaspiro[3.5]nonane-7-carboxylate serves as a versatile PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs) for targeted protein degradation. This compound enables precise conjugation of warheads for enhanced specificity and efficacy in therapeutic applications. Its structural attributes make it suitable for the creation of novel PROTAC molecules in chemical biology research. -
PROTAC Linker
16-(Benzyloxy)-16-oxohexadecanoic acid is a PROTAC linker that facilitates the development of proteolysis-targeting chimeras (PROTACs). This compound is instrumental in the design and synthesis of PROTAC molecules, enabling targeted protein degradation in therapeutic applications. Its structural properties enhance binding efficiency, supporting research in drug discovery and validation of protein targets. -
PROTAC Linker
3-(Azetidin-3-yl)propan-1-ol hydrochloride serves as a PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound is instrumental in synthesizing bifunctional molecules that promote the degradation of specific proteins, enabling targeted therapeutic strategies in cancer and other diseases. Its unique chemical properties enhance the efficiency and specificity of PROTAC formation, making it a valuable tool for researchers in chemical biology and drug discovery. -
PROTAC Linker
Tert-butyl 12-bromododecanoate is a PROTAC linker designed for the synthesis of Proteolysis Targeting Chimeras (PROTACs). This compound facilitates the targeted degradation of specific proteins by linking E3 ligases to proteins of interest, enhancing their selective ubiquitination and subsequent proteasomal degradation. Its utilization is pivotal in advancing research in targeted protein degradation, small molecule drug development, and related therapeutic strategies. -
PROTAC Linker
CH2Br-Bicyclo[1.1.1]pentane-COOH is a versatile PROTAC linker designed to facilitate the synthesis of Proteolysis Targeting Chimeras (PROTACs). This compound serves as a crucial component in the development of targeted protein degradation strategies, enabling researchers to selectively modulate protein levels within cells. Its unique structural characteristics enhance the effectiveness and specificity of PROTACs in various biological applications, making it a valuable tool in chemical biology and drug discovery. -
PROTAC Linker
Methyl 4-aminobicyclo[2.2.2]octane-1-carboxylate hydrochloride serves as a crucial linker in the development of PROTACs (proteolysis-targeting chimeras). This compound facilitates the construction of bifunctional molecules that promote the degradation of specific target proteins via the ubiquitin-proteasome system. Its application is significant in the fields of targeted protein degradation, cancer therapy research, and drug development. -
PROTAC Linker
18-Bromooctadecanoic acid serves as a PROTAC (Proteolysis Targeting Chimera) linker, facilitating the development of targeted protein degradation systems. Its unique structure enables effective conjugation to both the target protein and an E3 ligase, enhancing the efficiency of PROTACs in molecular research. This compound is crucial for studies investigating protein regulation and has applications in drug discovery and therapeutic development. -
PROTAC Linker
Cbz-PEG3-prop-1-yne is a PROTAC linker that facilitates the development of proteolysis-targeting chimeras (PROTACs). This compound serves as a versatile component in the synthesis of PROTACs, enabling targeted degradation of specific proteins. Its unique structural properties support effective ligand conjugation while maintaining the desired biological activity for protein modulation studies. -
PROTAC Linker
5-Cyano-1-pentyne is a potent PROTAC linker designed for the synthesis of Proteolysis Targeting Chimeras (PROTACs). This compound facilitates the recruitment of E3 ligases, enabling targeted protein degradation. 5-Cyano-1-pentyne is essential for researchers developing novel therapeutics that harness the ubiquitin-proteasome system for enhanced protein regulation and modulation in various biological contexts. -
PROTAC Linker
5-(Methylamino)pentan-1-ol is utilized as a PROTAC linker, facilitating the design and synthesis of proteolysis-targeting chimeras (PROTACs). This compound plays a crucial role in enhancing the specificity and efficacy of target protein degradation in biological research. It is commonly employed in investigations of targeted protein modulation and cellular degradation pathways. -
PROTAC Linker
8-Chlorooctan-1-ol is a PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the selective degradation of target proteins, thus enabling the study of protein function and cellular pathways. It is essential in advancing research in targeted protein degradation and therapeutic interventions in various diseases. -
PROTAC Linker
1,10-Dibromodecan serves as a versatile PROTAC linker, facilitating the synthesis of PROTACs that target specific proteins for degradation. Its unique brominated structure enhances the interaction between the target protein and E3 ligase, promoting efficient ubiquitination and subsequent proteasomal degradation. This compound is crucial for researchers developing targeted protein degradation strategies in various biological studies. -
PROTAC Linker
Tert-butyl (4-(aminomethyl)benzyl)(methyl)carbamate is a versatile PROTAC linker essential for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the construction of bifunctional molecules that recruit E3 ligases, allowing for targeted protein degradation. Its application in drug development research aids in the investigation of protein function and therapeutic interventions. -
PROTAC Linker
tert-Butyl 4-(2-cyanoacetyl)piperidine-1-carboxylate serves as a versatile PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound enables the selective degradation of target proteins by promoting the engagement of E3 ligases. It is essential for researchers aiming to design and synthesize innovative PROTACs for therapeutic applications. -
PROTAC Linker
2-(7-(Tert-butoxycarbonyl)-7-azaspiro[3.5]nonan-2-yl)acetic acid functions as a versatile PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound plays a crucial role in the design of bifunctional molecules that can modulate protein degradation pathways. Its structural features support efficient protein-protein interactions, making it suitable for targeted protein degradation studies and drug discovery applications. -
PROTAC Linker
Methyl 16-bromohexadecanoate serves as a PROTAC linker, facilitating the synthesis of bifunctional degraders. This compound is crucial for the development of targeted protein degradation strategies, enabling selective modulation of protein levels within cellular systems. Its application extends to various research areas, including drug discovery and the study of protein interactions. -
PROTAC Linker
16-Bromohexadecanoic acid is a PROTAC linker designed for the synthesis of proteolysis targeting chimeras (PROTACs). Its unique structure enhances the specificity and efficacy of these bifunctional molecules in targeted protein degradation. This compound is integral for research applications involving the modulation of protein levels and the investigation of cellular protein homeostasis. -
PROTAC Linker
Decane-1,10-diamine serves as a versatile PROTAC linker, facilitating the synthesis of proteolysis-targeting chimeras (PROTACs). This compound enhances the stability and efficacy of PROTACs by providing a flexible and robust connection between the target protein ligand and an E3 ligase ligand. Its application is crucial in the development of targeted protein degradation strategies in chemical biology research. -
PROTAC Linker
Hex-5-yn-1-yl 4-methylbenzenesulfonate is a PROTAC linker designed for use in the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates targeted protein degradation by bridging an E3 ligase with a protein of interest, enabling the selective modulation of protein levels within cells. Hex-5-yn-1-yl 4-methylbenzenesulfonate is essential for advancing research on targeted therapies and uncovering cellular mechanisms through the manipulation of protein homeostasis. -
PROTAC Linker
Benzyl (3-aminopropyl)carbamate functions as a PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound plays a crucial role in connecting E3 ligases with target proteins, thereby enabling selective degradation of unwanted proteins within cells. It is an essential tool for researchers investigating targeted protein degradation and its therapeutic potential in various disease models. -
PROTAC Linker
Tert-butyl-dimethyl-pent-4-ynoxy-silane is a versatile PROTAC linker that facilitates the construction of proteolysis-targeting chimeras (PROTACs). This compound enables the effective conjugation of target proteins to E3 ligases, thereby promoting targeted protein degradation. It is utilized in chemical biology research to investigate protein function and develop novel therapeutic strategies. -
PROTAC Linker
tert-Butyl 3-(3-hydroxypropyl)azetidine-1-carboxylate serves as a PROTAC linker for the development of protein-targeting chimeras. Its structure facilitates the conjugation of ligands to targeted proteins, promoting their selective degradation via the ubiquitin-proteasome pathway. This compound has significant applications in exploring protein function and developing therapeutics through targeted protein modulation. -
PROTAC Linker
N,N'-(Ethane-1,2-diyl)bis(2-bromoacetamide) is a PROTAC linker designed for the efficient synthesis of PROTACs. This compound facilitates the development of targeted protein degradation strategies by enabling the formation of bifunctional molecules that recruit E3 ubiquitin ligases to specific target proteins. Its application extends to various research areas, including drug discovery and therapeutic development in cancer and other diseases. -
PROTAC Linker
1,7-Heptanediol is a versatile PROTAC linker that facilitates the development of proteolysis-targeting chimeras (PROTACs). This compound is essential for conjugating target proteins to E3 ligases, thereby enhancing the targeted degradation of specific proteins in cellular contexts. Its application in drug discovery and molecular biology research supports studies focused on protein function modulation and therapeutic intervention strategies. -
PROTAC Linker
Methyl 12-bromododecanoate is a PROTAC linker characterized by its ability to facilitate the synthesis of protein-targeting chimeras. This compound enhances the engagement of E3 ligases in targeted protein degradation applications, making it a valuable tool in drug discovery and development efforts aimed at modulating protein levels within cells. Its distinct chemical properties support innovative research in targeted therapies and molecular biology studies. -
PROTAC Linker
tert-Butyl 3-(2-hydroxyethoxy)azetidine-1-carboxylate serves as a versatile PROTAC linker, facilitating the synthesis of proteolysis-targeting chimeras (PROTACs). This compound is instrumental in the development of targeted protein degradation strategies, enabling selective modulation of protein activity. Its effectiveness in creating bifunctional molecules makes it valuable for research in drug discovery and the study of protein homeostasis. -
PROTAC Linker
3,3'-(Propane-1,3-diylbis(oxy))bis(propan-1-ol) functions as a PROTAC linker, facilitating the development of proteolysis-targeting chimeras. This compound plays a critical role in assembling a ligand that recruits E3 ligases for targeted protein degradation. Its application in the synthesis of PROTACs supports investigations into targeted therapies and the modulation of specific protein levels for research in cellular signaling pathways and disease mechanisms. -
PROTAC Linker
PEG2-MeN-Boc is a polyethylene glycol-based linker designed for use in the synthesis of PROTACs (proteolysis-targeting chimeras). This compound enhances the solubility and stability of PROTACs, facilitating the targeted degradation of specific proteins. Its application is crucial in the development of novel therapeutic agents aimed at modulating protein levels for cancer and other diseases. -
PROTAC Linker
2-(4-(2-Methoxy-2-oxoethyl)phenyl)acetic acid is a PROTAC linker designed to facilitate the synthesis of proteolysis-targeting chimeras (PROTACs). This compound plays a crucial role in connecting target proteins to E3 ligases, thus enhancing targeted protein degradation. It is valuable in research focused on protein modulation and therapeutic development through innovative drug design strategies. -
PROTAC Linker
(9H-Fluoren-9-yl)methyl tert-butyl ethane-1,2-diyldicarbamate functions as a PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound is instrumental in connecting proteins of interest to E3 ligases for targeted degradation, thereby enhancing the specificity and efficacy of therapeutic interventions in various diseases. Its application in the synthesis of PROTACs underscores its significance in chemical biology and drug discovery research. -
PROTAC Linker
Cbz-NH-PEG2-CH2COOH is a polyethylene glycol (PEG)-based linker designed for use in the synthesis of PROTAC (proteolysis-targeting chimeras). This compound facilitates targeted protein degradation by linking a protein-targeting ligand with an E3 ligase ligand, enhancing the selective degradation of specific proteins. Its application in PROTAC development makes it a valuable tool for researchers investigating therapeutic strategies in various diseases, including cancer. -
PROTAC Linker
tert-Butyl (7-hydroxyheptyl)carbamate serves as a PROTAC linker, facilitating the connection between target proteins and ubiquitin ligases for targeted protein degradation. This compound is integral to the design and synthesis of PROTAC molecules, enabling researchers to manipulate protein levels with precision. Its unique structure enhances the efficiency and specificity of protein degradation in biological assays.
