Catalog No.
Product Name
Application
Product Information
Citations
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PROTAC Linker
Cbz-NH-PEG2-C2-acid is a PEG-based linker designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). This compound facilitates the selective degradation of target proteins by connecting E3 ligases with target proteins through a flexible linker architecture. Its unique structure enhances the efficacy and specificity of PROTAC development, making it a valuable tool for researchers in drug discovery and protein regulation studies. -
PROTAC Linker
Boc-N-Amido-PEG4-propargyl is a PEG-based linker designed for use in the synthesis of proteolysis-targeting chimeras (PROTACs). Its alkyne functionality enables efficient copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing compounds. This reagent serves as a valuable tool in chemical biology research, facilitating the development of targeted protein degradation strategies. -
PROTAC Linker
Biotin-PEG3-CH2COOH is a PEG-based PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the selective degradation of target proteins via the ubiquitin-proteasome pathway, aiding in the exploration of proteomic interactions and therapeutic potential. Its biotin moiety allows for easy detection and purification, making it an essential tool for researchers in drug discovery and cellular biology. -
PROTAC Linkers
m-PEG5-NHS ester is a polyethylene glycol (PEG)-based linker specifically designed for the synthesis of PROTACs (proteolysis-targeting chimeras). This compound enables the conjugation of proteins, facilitating the targeted degradation of specific proteins within cellular environments. It is a valuable tool for researchers studying protein-protein interactions, targeted protein degradation, and the development of novel therapeutic strategies. -
PROTAC Linkers
Methyltetrazine-PEG8-PFP ester is a PEG-based linker designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). This compound effectively facilitates the formation of targeted protein degradation complexes by linking the E3 ligase to the protein of interest. Its unique structure enhances solubility and bioavailability, making it suitable for various applications in chemical biology and drug discovery. -
PROTAC Linker
Mal-PEG2-NH2 serves as a polyethylene glycol (PEG)-based linker for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the formation of PROTACs by linking E3 ligases to target proteins, promoting targeted degradation. Its use is critical in drug discovery, advancing the development of therapeutic agents that can selectively eliminate specific proteins within biological systems. -
PROTAC Linkers
Br-PEG6-C2-NHBoc is a PEG-based linker designed for PROTAC (Proteolysis Targeting Chimeras) synthesis. It facilitates the conjugation of target proteins to E3 ligases, enhancing the efficiency of targeted protein degradation. This compound is integral for researchers developing innovative therapeutic strategies in cancer, neurodegenerative diseases, and other conditions where selective protein modulation is beneficial. -
PROTAC Linkers
Tos-PEG5-Boc is a PEG-based PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). This linker facilitates the conjugation of target proteins with E3 ligases, enhancing targeted protein degradation. Its unique structure enables improved solubility and optimal flexibility, making it a valuable tool for researchers exploring targeted therapies and protein modulation in diverse biological studies. -
PROTAC Linker
Propargyl-PEG2-CH2COOH is a PEG-based linker designed for the synthesis of PROTACs, functioning through the formation of stable covalent bonds. This compound features an alkyne moiety that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with azide-containing molecules. Its application in PROTAC development supports targeted protein degradation studies, making it a valuable tool for researchers investigating cellular mechanisms and therapeutic interventions. -
PROTAC Linker
Boc-NH-PEG2-CONH-PEG2-COOH is a synthesized PROTAC linker that facilitates the design of proteolysis targeting chimeras (PROTACs). This compound effectively connects target proteins to E3 ligases, enhancing targeted protein degradation. It is suitable for use in research focused on therapeutic applications, particularly in the study of protein regulation and degradation pathways. -
PROTAC Linker
(Tert-Butyldimethylsiloxy)Acetaldehyde is a versatile PROTAC linker designed to facilitate the development of targeted protein degraders. This compound enables the efficient synthesis of PROTACs, which are utilized in drug discovery and development to modulate protein levels by harnessing the ubiquitin-proteasome system. Its structural features make it suitable for assembling novel degrader constructs in various biological research applications. -
PROTAC Linker
Tert-butyl 4-(piperazine-1-carbonyl)piperidine-1-carboxylate functions as a PROTAC linker, facilitating the development of Proteolysis Targeting Chimeras (PROTACs). This compound enhances the selective degradation of target proteins through ubiquitin-proteasome pathways, making it valuable for drug discovery and chemical biology research focused on targeted protein degradation. Its unique chemical structure provides robustness in PROTAC design, contributing to advancements in therapeutic applications. -
PROTAC Linker
tert-Butyl 4-(aminomethyl)-4-fluoropiperidine-1-carboxylate serves as a versatile PROTAC linker designed for targeted protein degradation applications. By facilitating the conjugation of target proteins with E3 ligases, this compound enhances the functionalization of PROTACs, enabling precision in drug development. It is particularly valuable in the synthesis of innovative therapeutics for a range of diseases. -
PROTAC Linker
((6-Bromohexyl)oxy)(tert-butyl)dimethylsilane serves as a versatile PROTAC linker, essential for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the selective degradation of target proteins, enabling studies in targeted protein elimination and therapeutic development. Its unique structure supports effective conjugation strategies in drug discovery and basic research applications. -
PROTAC Linker
4-Aminobutanenitrile hydrochloride is a crucial component utilized as a linker in the synthesis of Proteolysis Targeting Chimeras (PROTACs). This reagent facilitates the development of targeted protein degradation systems, enhancing the ability to modulate specific protein levels within cells. Its application is significant in advancing drug discovery and therapeutic development, particularly in oncology and other disease pathways where protein regulation is critical. -
PROTAC Linker
4-Chlorobutan-1-amine hydrochloride is a versatile PROTAC linker utilized in the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the conjugation of target proteins to E3 ligases, enabling selective degradation pathways in cellular systems. It is valuable in various research applications aimed at investigating protein function and therapeutic interventions through targeted protein degradation. -
PROTAC Linker
tert-Butyl 6-amino-2-azaspiro[3.3]heptane-2-carboxylate hydrochloride is a PROTAC linker designed for the development of proteolysis-targeting chimeras (PROTACs). This compound facilitates the recruitment of E3 ligases to target proteins, promoting their ubiquitination and subsequent degradation. Its application in synthetic biology allows for targeted modulation of protein levels, making it a valuable tool in chemical biology and therapeutic research. -
PROTAC Linker
7-Boc-(7-Azaspiro[3.5]nonane)-2-methanamine is a specialized linker for PROTAC (proteolysis-targeting chimeras) synthesis, facilitating the targeted degradation of specific proteins within cells. It plays a critical role in the design and development of novel therapeutic agents by linking target proteins to E3 ligases, enhancing the efficacy of the PROTAC technology in cancer research and other applications in cellular biology. This compound enables researchers to explore the potential of targeted protein degradation strategies in drug discovery. -
PROTAC Linker
tert-Butyl (4-bromobenzyl)(methyl)carbamate is a specialized linker for PROTAC (proteolysis-targeting chimeras) development. This compound facilitates the design and synthesis of PROTACs by enabling the selective degradation of target proteins through targeted ubiquitination. Its application is crucial in studying cellular mechanisms and therapeutic strategies in various diseases, particularly in oncology and pharmacology research. -
PROTAC Linker
2,2-Oxybis(ethylamine) dihydrochloride is a novel PROTAC linker designed to facilitate the targeted degradation of proteins via the ubiquitin-proteasome system. This compound serves as a key structural component in the synthesis of PROTAC molecules, enhancing their therapeutic potential. Its unique chemical properties enable selective modulation of protein stability, making it a valuable tool in drug discovery and development efforts. Researchers can utilize this linker in various biochemical applications to explore targeted protein degradation pathways. -
PROTAC Linker
1,9-Dibromononane serves as a versatile PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs) for targeted protein degradation. This compound plays a crucial role in the design and synthesis of innovative therapeutics aimed at modulating protein levels in various biological contexts. Its unique structure supports the formation of effective and selective PROTACs for research applications in drug discovery and cellular biology. -
PROTAC Linker
Cyano-C2-PEG3-cyano is a PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound provides a strategic connection between the E3 ligase and the target protein, enhancing the targeted degradation of specific proteins within cellular systems. Its versatility in linker design makes it suitable for various applications in drug discovery and development, particularly in the context of targeted protein degradation strategies. -
PROTAC Linker
2-(4-(Methoxycarbonyl)phenoxy)acetic acid serves as a PROTAC linker, facilitating the design and synthesis of proteolysis-targeting chimeras (PROTACs). This compound plays a crucial role in the effective modulation of protein degradation pathways, thereby supporting research in targeted protein degradation and therapeutic development. Its unique structural features enhance the specificity and efficacy of PROTACs, making it a valuable tool in chemical biology and drug discovery. -
PROTAC Linker
3-(4-Aminophenyl)propionic acid functions as a key PROTAC linker, facilitating the synthesis of Proteolysis Targeting Chimera (PROTAC) molecules. This compound plays a crucial role in the development of targeted protein degradation strategies, enabling selective modulation of protein levels in cellular environments. Its application in research is vital for uncovering the mechanisms of action in various signaling pathways and therapeutic approaches. -
PROTAC Linker
tert-Butyl 2-(piperidin-4-yl)acetate oxalate is a PROTAC linker designed to facilitate the synthesis of proteolysis-targeting chimeras (PROTACs). This compound plays a crucial role in the assembly of PROTACs, which are utilized to selectively degrade target proteins, providing valuable tools for research in targeted protein degradation and therapeutic development. Its structural properties enhance the efficiency and specificity of PROTAC design in various biological applications. -
PROTAC Linker
tert-Butyl ((trans-4-aminocyclohexyl)methyl)carbamate is an effective PROTAC linker utilized in the design and synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the targeted degradation of specific proteins, enabling researchers to manipulate cellular pathways and study protein function. Its versatile application in chemical biology makes it an important tool for advancing therapeutic strategies. -
PROTAC Linker
13-Bromotridecanoic acid serves as a PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound enables the selective degradation of target proteins, making it a valuable tool for dissecting biological pathways and validating therapeutic targets. Its role in linking ubiquitin ligases to target proteins expands its applications in drug discovery and protein engineering research. -
PROTAC Linker
Methyl 3-chlorobicyclo[1.1.1]pentane-1-carboxylate serves as a critical linker in the development of PROTAC (Proteolysis Targeting Chimeras) molecules. This compound facilitates the formation of PROTACs by connecting a ligand that recruits an E3 ubiquitin ligase to a target protein, thereby promoting targeted protein degradation. Its application is vital in drug discovery and development, particularly for studying protein function and regulating cellular pathways. -
PROTAC Linker
8-((tert-Butoxycarbonyl)amino)octyl 4-methylbenzenesulfonate serves as a PROTAC linker, facilitating the creation of targeted protein degradation molecules. This linker is integral in the design of PROTACs, enabling the selective degradation of specific proteins within cellular environments. Its unique chemical structure contributes to improved stability and effectiveness, making it a valuable tool for researchers focused on investigating protein functions and therapeutic strategies. -
PROTAC Linker
Methyl 3-aminocyclobutane-1-carboxylate hydrochloride is a key PROTAC linker that facilitates the design and synthesis of proteolysis-targeting chimeras (PROTACs). This compound plays a critical role in promoting targeted protein degradation by linking substrates to E3 ligases, thereby enhancing the efficacy of targeted therapies. Its utility in chemical biology and drug discovery makes it an essential reagent for researchers developing novel therapeutics in various disease models. -
PROTAC Linker
tert-Butyl methyl(3-oxopropyl)carbamate serves as a PROTAC linker, facilitating the development of targeted protein degradation technologies. This compound is instrumental in the synthesis of PROTAC molecules, enabling researchers to selectively degrade specific proteins within cellular environments. Its structural versatility supports various applications in drug discovery and development, particularly in targeting previously undruggable proteins. -
PROTAC Linker
1,1-Dimethylethyl 4-iodobutanoate serves as a PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). Its unique chemical properties allow for the efficient conjugation of targeted proteins, enabling researchers to engage the ubiquitin-proteasome system for targeted degradation. This compound is valuable in studies focused on protein modulation and therapeutic applications in oncology and cellular regulation. -
PROTAC Linker
tert-Butyl (3-(piperidin-4-yl)propyl)carbamate is a PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the dual-targeting capability of PROTACs, enabling the selective degradation of specific proteins within cells. Its application is essential in studies focused on targeted protein degradation and the development of novel therapeutic strategies in various disease models. -
PROTAC Linker
Methyl 10-bromodecanoate functions as a PROTAC linker, facilitating the development of targeted protein degrader molecules. Its unique structural properties enable efficient conjugation to E3 ligase and target proteins, thereby promoting protein degradation pathways. This compound is valuable in the field of chemical biology for the synthesis of novel PROTACs aimed at exploring protein function and therapeutic strategies. -
PROTAC Linker
Sebaconitrile is a key PROTAC linker utilized in the synthesis of Proteolysis Targeting Chimeras (PROTACs). Its structure facilitates efficient binding and degradation of target proteins via the ubiquitin-proteasome pathway. This compound is essential for research applications focused on the modulation of protein levels and therapeutic targeting of specific proteins for cancer and other diseases. -
PROTAC Linker
tert-Butyl (4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenethyl)carbamate is a specialized PROTAC linker that facilitates the development of proteolysis-targeting chimera (PROTAC) molecules. This reagent plays a critical role in connecting target proteins with E3 ligases, enabling targeted protein degradation. Its unique structure enhances the efficiency and specificity of PROTAC synthesis, making it essential for research in therapeutic strategies aimed at selective protein modulation. -
PROTAC Linker
OH-PEG2-C3-NH2 is a PROTAC linker designed to facilitate the synthesis of proteolysis-targeting chimeras (PROTACs). Its chemical structure enables efficient conjugation to target proteins, enhancing targeted degradation pathways. This linker is pivotal for studies focused on protein modulation and therapeutic development through targeted protein degradation strategies. -
PROTAC Linker
tert-Butyl (1-(2-aminoethyl)piperidin-4-yl)carbamate functions as a PROTAC linker, facilitating the development of Proteolysis Targeting Chimeras (PROTACs). This compound is integral for connecting target proteins to E3 ligases, enhancing specific ubiquitination and subsequent degradation of the target. Its application is crucial in the field of targeted protein degradation research, offering insights into protein regulation and therapeutic intervention. -
PROTAC Linker
Cbz-NH-PEG1-CH2COOH is a polyethylene glycol (PEG)-based linker designed for use in the synthesis of PROTACs (proteolysis-targeting chimeras). This compound facilitates the conjugation of target proteins to E3 ligases, enhancing the degradation of unwanted proteins in cellular contexts. Its application is crucial for researchers focusing on targeted protein degradation and the development of novel therapeutic strategies. -
PROTAC Linker
tert-Butyl 5-hydroxypentanoate serves as a key PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs) for targeted protein degradation. Its structural features enable effective conjugation with various protein-binding domains, enhancing the specificity and efficiency of PROTAC design. This compound is valuable in chemical biology research aimed at modulating protein levels within cells for therapeutic applications. -
PROTAC Linker
1,8-Octanedithiol is a versatile PROTAC linker that facilitates the assembly of proteolysis-targeting chimeras (PROTACs). Its unique structure allows for effective conjugation to target proteins and E3 ligases, enhancing the specificity and efficacy of targeted degradation strategies in research. This compound is essential for the development of novel therapeutic agents aimed at modulating protein levels in various biological pathways. -
PROTAC Linker
Dimethyl spiro[3.3]heptane-2,6-dicarboxylate functions as a PROTAC linker, facilitating the synthesis of proteolysis-targeting chimeras (PROTACs). This compound plays a crucial role in the development of targeted protein degradation strategies, enhancing the efficacy and selectivity of therapeutic agents. Its structural properties make it suitable for various research applications involving the modulation of protein levels in cellular systems. -
PROTAC Linker
Br-PEG7-Br is a PEG-based linker designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). Its structure facilitates the conjugation of target proteins to E3 ligases, enabling targeted protein degradation. This compound is essential for researchers developing innovative therapeutic strategies in drug discovery and cellular biology studies. -
PROTAC Linker
(4-(((Tert-butoxycarbonyl)(methyl)amino)methyl)phenyl)boronic acid functions as a key PROTAC (Proteolysis Targeting Chimera) linker. This compound facilitates the assembly of PROTACs by connecting a target ligand to an E3 ligase ligand, thereby enabling the ubiquitin-proteasome system to selectively degrade the target protein. Its application is critical in studies aimed at exploring targeted protein degradation and drug discovery processes. -
PROTAC Linker
1,10-Dichlorodecane serves as a PROTAC linker, facilitating the construction of Proteolysis Targeting Chimeras (PROTACs). Its unique chemical structure allows for effective conjugation of target proteins with E3 ligases, promoting targeted protein degradation. This compound is essential for studies focusing on targeted therapeutics and the modulation of protein levels in various biological systems. -
PROTAC Linker
6-Chlorohexanoic acid is a versatile PROTAC linker that facilitates the synthesis of proteolysis-targeting chimeras (PROTACs). This compound enhances the development of targeted protein degradation technologies, making it a valuable reagent for drug discovery and biological research. Its structural properties enable efficient conjugation to various proteins, contributing to innovative therapeutic strategies. -
PROTAC Linker
tert-Butyl 4-(3-hydroxypropyl)piperazine-1-carboxylate serves as a versatile PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound enhances the efficacy of targeted protein degradation strategies by enabling selective binding to ubiquitin ligases. Its structural properties make it suitable for applications in drug discovery and the study of protein regulation mechanisms. -
PROTAC Linker
Methyl 3-(4-aminophenyl)propanoate serves as a versatile PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). Its unique structure enables effective conjugation to target proteins, thereby enhancing the potential for selective protein degradation. This compound is valuable in biochemical research focusing on targeted protein modulation and therapeutic applications in the study of various diseases. -
PROTAC Linker
6-((2,5-Dioxopyrrolidin-1-yl)oxy)-6-oxohexanoic acid is a bifunctional linker designed for the synthesis of PROTACs (Proteolysis Targeting Chimeras). This reagent facilitates the selective degradation of target proteins by linking an E3 ligase to the protein of interest. Its unique structure offers versatility in tailoring PROTACs for specific biological applications, making it an essential tool for researchers exploring targeted protein degradation mechanisms. -
PROTAC Linker
tert-Butyl 16-bromohexadecanoate is a PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the conjugation of target proteins and E3 ligases, enhancing targeted degradation pathways. Its precise structure supports efficient development of novel therapeutic agents for various diseases, particularly in the field of targeted protein degradation research.
