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PYZ18

Catalog No.: A64503
COX-2 Inhibitor
PYZ18 is a selective inhibitor of cyclooxygenase-2 (COX-2) with an IC50 value of 7.07 μM. This compound demonstrates significant anti-inflammatory properties, making it a valuable tool in the study of inflammatory diseases. PYZ18 is suitable for research applications exploring COX-2 inhibition and its potential therapeutic effects.
PYZ18 1447578-01-9 COX-2 Inhibitor
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionPYZ18 is a selective inhibitor of cyclooxygenase-2 (COX-2) with an IC50 value of 7.07 μM. This compound demonstrates significant anti-inflammatory properties, making it a valuable tool in the study of inflammatory diseases. PYZ18 is suitable for research applications exploring COX-2 inhibition and its potential therapeutic effects.
Product Information
Catalog NumA64503
FormulaC18H14F3N3S
Molecular Weight361.38
CAS Number1447578-01-9
SMILESFC(F)(C1=NN(C(C2=CC=C(C)C=C2)=C1)C3=CC=C(C(N)=S)C=C3)F
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Immunology & Inflammation > COX
Neuronal Signaling > COX