Catalog No.: A10802
Gamma-secretase inhibitor
RO4929097 is an orally bioavailable, small-molecule gamma secretase (GS) inhibitor with an IC50 of 4 nM.
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RO4929097 10mM * 1mL in DMSO
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Adooq Products cited in reputable paper
Adooq's RO4929097 has been cited by 1 publications
  • Hirosumi Tamura, .et al. , Oncol Rep, 2018, Aug; 40(2): 635-646 PMID: 29917168
  • Biological Activity
    Discription RO4929097 is an orally bioavailable, small-molecule gamma secretase (GS) inhibitor with an IC50 of 4 nM.
    Target Value
    Product Information
    Catalog Num A10802
    Formula C22H20F5N3O3
    Molecular Weight 469.4
    CAS Number 847925-91-1

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    In vitro (25°C) DMSO 92 mg/mL (195.99 mM)
    Water Insoluble
    Ethanol 16 mg/mL
    In vivo 2% DMSO+30% PEG 300+5% Tween+ddH2O 9 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 21.3 mL 106.52 mL 213.04 mL
    0.5 mM 4.26 mL 21.3 mL 42.61 mL
    1 mM 2.13 mL 10.65 mL 21.3 mL
    5 mM 0.43 mL 2.13 mL 4.26 mL
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    Calculate the dilution required to prepare a stock solution.
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