Rofecoxib (Vioxx)

Catalog No.: A11918

COX-2 inhibitor

Rofecoxib (Vioxx) Chemical Structure

CAS NO. 162011-90-7

Rofecoxib (Vioxx) is a?COX-2?inhibitor with?IC5N/A?of 18 nM.

Availability: In stock

Package Price Qty
250 mg
$80.00
500 mg
$150.00
1000 mg
$250.00
2000 mg
$400.00
10mM * 1mL in DMSO
$60.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Rofecoxib (Vioxx) is a?COX-2?inhibitor with?IC5N/A?of 18 nM.
Targets
COX-2
18 nM
In vitro (25°C) DMSO 63 mg/mL (200.4 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 31.81 mL 159.06 mL 318.12 mL
0.5 mM 6.36 mL 31.81 mL 63.62 mL
1 mM 3.18 mL 15.91 mL 31.81 mL
5 mM 0.64 mL 3.18 mL 6.36 mL

*The above data is based on the productmolecular weight 314.35. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11918
Actions Inhibitor
M. Wt 314.35
Formula C17H14O4S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 162011-90-7
Synonyms Vioxx
SMILES CS(=O)(=O)C1=CC=C(C=C1)C2=C(C(=O)OC2)C3=CC=CC=C3

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