SC-75416

Catalog No.: A64419
COX Inhibitor
SC-75416 is a selective inhibitor of cyclooxygenase-2 (COX-2), primarily designed to mitigate pain and inflammation. Its pharmacokinetic/pharmacodynamic (PK/PD) model has been utilized to develop clinical trial simulations that support its analgesic efficacy, demonstrated to exceed that of ibuprofen in post-oral surgery pain models. The results from these simulations and subsequent clinical trials indicate that SC-75416 offers superior pain relief, underscoring its potential as a valuable therapeutic agent for managing postoperative pain.
Grouped product items
Size Price Stock Qty
1mg
$235.00
In stock
5mg
$590.00
In stock
10mg
$830.00
In stock
25mg
$1,275.00
In stock
50mg
$1,625.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionSC-75416 is a selective inhibitor of cyclooxygenase-2 (COX-2), primarily designed to mitigate pain and inflammation. Its pharmacokinetic/pharmacodynamic (PK/PD) model has been utilized to develop clinical trial simulations that support its analgesic efficacy, demonstrated to exceed that of ibuprofen in post-oral surgery pain models. The results from these simulations and subsequent clinical trials indicate that SC-75416 offers superior pain relief, underscoring its potential as a valuable therapeutic agent for managing postoperative pain.
Product Information
Catalog NumA64419
FormulaC15H14ClF3O3
Molecular Weight334.72
CAS Number215122-74-0
SMILESO=C(C1=CC2=CC(Cl)=C(C(C)(C)C)C=C2O[C@@H]1C(F)(F)F)O
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