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$0.00 Biological Activity
Sorafenib (Bay 43-9006) is a potent, orally active multikinase inhibitor with IC50s of 6 nM, 20 nM, and 22 nM for Raf-1, B-Raf, and VEGFR-3, respectively.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.51 mL | 107.57 mL | 215.13 mL |
| 0.5 mM | 4.3 mL | 21.51 mL | 43.03 mL |
| 1 mM | 2.15 mL | 10.76 mL | 21.51 mL |
| 5 mM | 0.43 mL | 2.15 mL | 4.3 mL |
*The above data is based on the productmolecular weight 464.83. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A17857 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 464.83 |
| Formula | C21H16ClF3N4O3 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 284461-73-0 |
| Synonyms | Bay 43-9006, Bay-43-9006, Bay43-9006 |
| SMILES | O=C(NC(C=C1)=CC=C1OC2=CC(C(NC)=O)=NC=C2)NC3=CC=C(Cl)C(C(F)(F)F)=C3 |
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