Sorafenib (D4)

Catalog No.: A21495

Raf/VEGFR3 inhibitor

Sorafenib D4 (Bay 43-9006 D4) is the deuterium labeled Sorafenib. Sorafenib is a multikinase inhibitor IC50s of 6 nM, 20 nM, and 22 nM for Raf-1, B-Raf, and VEGFR-3, respectively.
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Product Name Price Stock Qty
Sorafenib (D4) 1mg
Special Price $256.00 Regular Price $320.00
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Sorafenib (D4) 5mg
Special Price $768.00 Regular Price $960.00
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Sorafenib (D4) 10mg
Special Price $1,280.00 Regular Price $1,600.00
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Biological Activity
Discription Sorafenib D4 (Bay 43-9006 D4) is the deuterium labeled Sorafenib. Sorafenib is a multikinase inhibitor IC50s of 6 nM, 20 nM, and 22 nM for Raf-1, B-Raf, and VEGFR-3, respectively.
Product Information
Catalog Num A21495
Formula C21H12D4ClF3N4O3
Molecular Weight 468.85
CAS Number 1207560-07-3
SMILES O=C(C1=NC=CC(OC2=C([2H])C([2H])=C(NC(NC3=CC=C(Cl)C(C(F)(F)F)=C3)=O)C([2H])=C2[2H])=C1)NC
Synonyms Bay 43-9006 (D4)
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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