Sorafenib (D4)

Catalog No.: A21495

multikinase inhibitor

Sorafenib (D4)

Sorafenib (D4) Chemical Structure

CAS NO. 1207560-07-3

Sorafenib D4 (Bay 43-9006 D4) is the deuterium labeled Sorafenib. Sorafenib is a multikinase inhibitor IC50s of 6 nM, 20 nM, and 22 nM for Raf-1, B-Raf, and VEGFR-3, respectively.

Availability: In stock

Package Price Qty
1 mg
$320.00
5 mg
$960.00
10 mg
$1,600.00
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Biological Activity

Sorafenib D4 (Bay 43-9006 D4) is the deuterium labeled Sorafenib. Sorafenib is a multikinase inhibitor IC50s of 6 nM, 20 nM, and 22 nM for Raf-1, B-Raf, and VEGFR-3, respectively.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.33 mL 106.64 mL 213.29 mL
0.5 mM 4.27 mL 21.33 mL 42.66 mL
1 mM 2.13 mL 10.66 mL 21.33 mL
5 mM 0.43 mL 2.13 mL 4.27 mL

*The above data is based on the productmolecular weight 468.85. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21495
Actions Inhibitor
M. Wt 468.85
Formula C21H12D4ClF3N4O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1207560-07-3
Synonyms Bay 43-9006 (D4)
SMILES O=C(C1=NC=CC(OC2=C([2H])C([2H])=C(NC(NC3=CC=C(Cl)C(C(F)(F)F)=C3)=O)C([2H])=C2[2H])=C1)NC

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