Biological Activity
SPL-707 is a potent, selective and orally available signal peptide peptidase-like 2a (SPPL2a) inhibitor with an IC50 of 80 nM.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 19.78 mL | 98.9 mL | 197.81 mL |
0.5 mM | 3.96 mL | 19.78 mL | 39.56 mL |
1 mM | 1.98 mL | 9.89 mL | 19.78 mL |
5 mM | 0.4 mL | 1.98 mL | 3.96 mL |
*The above data is based on the productmolecular weight 505.54. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A13669 |
---|---|
Actions | Inhibitor |
CAS No. | 2195361-33-0 |
Formula | C27H28FN5O4 |
M. Wt | 505.54 |
Purity | >98% |
Synonyms | SPL 707, SPL707 |
SMILES | CC1=C(NC(C[[email protected]@H](C2CC2)C(N[[email protected]@H]3C(N(CC4(CC4)C5)N5C(C6=C3C=CC=C6)=O)=O)=O)=O)C=C(F)C=N1 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
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