TCO-PEG4-acid is a polyethylene glycol (PEG)-based linker designed for use in the synthesis of proteolysis-targeting chimeras (PROTACs). This compound serves as an effective spacer, facilitating the coupling of E3 ligase recruiters and target proteins, thereby enhancing the degradation of specific proteins in cellular assays. Its application in PROTAC development supports investigations into targeted protein degradation and therapeutic strategies in various diseases.
TCO-PEG4-acid is a polyethylene glycol (PEG)-based linker designed for use in the synthesis of proteolysis-targeting chimeras (PROTACs). This compound serves as an effective spacer, facilitating the coupling of E3 ligase recruiters and target proteins, thereby enhancing the degradation of specific proteins in cellular assays. Its application in PROTAC development supports investigations into targeted protein degradation and therapeutic strategies in various diseases.
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