TCO-PEG8-amine

Catalog No.: A82993
PROTAC Linkers
TCO-PEG8-amine is a polyethylene glycol (PEG)-based linker designed for the synthesis of PROTACs (proteolysis targeting chimeras). It facilitates the formation of bifunctional molecules by covalently linking target proteins to E3 ligases, enabling targeted protein degradation. This reagent is essential for researchers exploring innovative therapeutic strategies in cancer, neurodegenerative diseases, and other pathologies through targeted modulation of protein levels.
Grouped product items
Size Price Stock Qty
5mg
$100.00
In stock
10mg
$170.00
In stock
25mg
$345.00
In stock
50mg
$540.00
In stock
100mg
$840.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionTCO-PEG8-amine is a polyethylene glycol (PEG)-based linker designed for the synthesis of PROTACs (proteolysis targeting chimeras). It facilitates the formation of bifunctional molecules by covalently linking target proteins to E3 ligases, enabling targeted protein degradation. This reagent is essential for researchers exploring innovative therapeutic strategies in cancer, neurodegenerative diseases, and other pathologies through targeted modulation of protein levels.
Product Information
Catalog NumA82993
FormulaC27H52N2O10
Molecular Weight564.71
CAS Number2353409-92-2
SMILESO=C(OC1CC/C=C\CCC1)NCCOCCOCCOCCOCCOCCOCCOCCOCCN
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Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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