TCO-PEG9-maleimide

Catalog No.: A82196
PROTAC Linkers
TCO-PEG9-maleimide is a PEG-based linker designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). It facilitates the conjugation of targeting moieties and E3 ligase recruiting units, enabling the effective degradation of selected proteins. This linker is particularly valuable in chemical biology and drug discovery research, where targeted protein degradation mechanisms are being explored for therapeutic development.
Grouped product items
Size Price Stock Qty
10mg
$270.00
In stock
25mg
$540.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionTCO-PEG9-maleimide is a PEG-based linker designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). It facilitates the conjugation of targeting moieties and E3 ligase recruiting units, enabling the effective degradation of selected proteins. This linker is particularly valuable in chemical biology and drug discovery research, where targeted protein degradation mechanisms are being explored for therapeutic development.
Product Information
Catalog NumA82196
FormulaC36H61N3O14
Molecular Weight759.88
CAS Number2183440-37-9
SMILESO=C(OC1CC/C=C\CCC1)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCN2C(C=CC2=O)=O)=O
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