Telaprevir (VX-950)

Catalog No.: A10902

HCV NS3-4A protease inhibitor

Telaprevir (VX-950) Chemical Structure

CAS NO. 402957-28-2

Telaprevir (VX-950) is known as protease inhibitors that inhibits the hepatitis C virus NS3.4A serine protease.

Availability: In stock

Package Price Qty
2 mg
5 mg
10 mg
25 mg
10mM * 1mL in DMSO

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Biological Activity

Telaprevir (VX-950) is known as protease inhibitors that inhibits the hepatitis C virus NS3.4A serine protease.
HCV NS3-4A serine protease
0.35 μM
In vitro (25°C) DMSO 136 mg/mL (200.04 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 14.71 mL 73.54 mL 147.08 mL
0.5 mM 2.94 mL 14.71 mL 29.42 mL
1 mM 1.47 mL 7.35 mL 14.71 mL
5 mM 0.29 mL 1.47 mL 2.94 mL

*The above data is based on the productmolecular weight 679.9 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10902
Actions Inhibitor
M. Wt 679.9
Formula C36H53N7O6
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 402957-28-2
Synonyms VX950, Incivek, Incivo
SMILES CCC[[email protected]@H](C(=O)C(=O)NC1CC1)NC(=O)[[email protected]@H]2[[email protected]]3CCC[[email protected]]3CN2C(=O)[[email protected]](C(C)(C)C)NC(=O)[[email protected]](C4CCCCC4)NC(=O)C5=NC=CN=C5

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