Telaprevir (VX-950)

Name: Telaprevir (VX-950)
SKU: A10902
Price: 35 USD
Rating: 5 (9 reviews)

Catalog No.: A10902

HCV NS3-4A protease inhibitor

Adooq's Telaprevir (VX-950) has been cited by 9 publications

Telaprevir (VX-950) is known as protease inhibitors that inhibits the hepatitis C virus NS3.4A serine protease.

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Grouped product items
Size	Price	Stock
1mg	$35.00	In stock
2mg	$55.00	In stock
5mg	$85.00	In stock
10mg	$155.00	In stock
25mg	$250.00	In stock
50mg	$350.00	In stock
100mg	$650.00	In stock
*10mM 1mL in DMSO**	$170.00	In stock
Bulk Size	Bulk Discount

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Important Notice: For research use only. We do not sell to patients.

Data Sheet

SDS

Adooq Products cited in reputable paper

Adooq's Telaprevir (VX-950) has been cited by 9 publications

Mahim Khan, .et al. , BMC Complement Med Ther, 2022, Apr 2;22(1):98 PMID: 35366855

Adita Ayu Permanasari, .et al. , BMC Complement Med Ther, 2021, Oct 12;21(1):260 PMID: 34641875

Che C Colpitts, .et al. , eLife, 2020, 9: e52237 PMID: 32539931

TS Wahyuni, .et al. , Southeast Asian J Trop Med public health, 2020, 51(1)

Stefan Bittmann, .et al. , J Regen Biol Med, 2020, 2(2):1-3

Wahyuni TS, .et al. , J Basic Clin Physiol Pharmacol, 2019, Dec 14 PMID: 31837259

Jacobs CL, .et al. , Nat Methods, 2018, Jul;15(7):523-526 PMID: 29967496

Apriyanto DR, .et al. , Jpn J Infect Dis, 2016, May 20;69(3):213-20 PMID: 26255732

Mizuki Yamamoto, .et al. , Antimicrob Agents Chemother, 2016, Nov; 60(11): 6532-6539 PMID: 27550352

Biological Activity

Discription

Telaprevir (VX-950) is known as protease inhibitors that inhibits the hepatitis C virus NS3.4A serine protease.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

Product Information

Catalog Num	A10902
Formula	C36H53N7O6
Molecular Weight	679.9
CAS Number	402957-28-2
SMILES	CCC[C@@H](C(=O)C(=O)NC1CC1)NC(=O)[C@@H]2[C@H]3CCC[C@H]3CN2C(=O)[C@H](C(C)(C)C)NC(=O)[C@H](C4CCCCC4)NC(=O)C5=NC=CN=C5
Synonyms	VX950, Incivek, Incivo
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility

In vitro (25°C)	DMSO	131 mg/mL (192.69 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	30% PEG400+0.5% Tween80+5% propylene glycol	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	14.71 mL	73.54 mL	147.08 mL
0.5 mM	2.94 mL	14.71 mL	29.42 mL
1 mM	1.47 mL	7.35 mL	14.71 mL
5 mM	0.29 mL	1.47 mL	2.94 mL

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