Thiomarinol A, a potent antibiotic, primarily targets bacterial isoleucyl-tRNA synthetase (IleRS), particularly in methicillin-resistant Staphylococcus aureus (MRSA). This compound, a hybrid of dithiolopyrrolone and marinolic acid, demonstrates significant antimicrobial activity through a dose-dependent inhibition, with a Kiapp value of 19 nM. Thiomarinol A is valuable for research applications focused on antibiotic development and the study of resistant bacterial strains.
Thiomarinol A, a potent antibiotic, primarily targets bacterial isoleucyl-tRNA synthetase (IleRS), particularly in methicillin-resistant Staphylococcus aureus (MRSA). This compound, a hybrid of dithiolopyrrolone and marinolic acid, demonstrates significant antimicrobial activity through a dose-dependent inhibition, with a Kiapp value of 19 nM. Thiomarinol A is valuable for research applications focused on antibiotic development and the study of resistant bacterial strains.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
