Torin 2

Catalog No.: A11586
mTOR inhibitor
Torin 2 is a potent and selective mTOR inhibitor (IC50 = 2.1 nM). Displays 800-fold cellular selectivity for mTOR over PI3K (cellular EC50 values are 0.25 and 200 nM for mTOR and PI3K respectively).
Grouped product items
Product Name Price Stock Qty
Torin 2 10mg
$110.00
In stock
Torin 2 25mg
$200.00
In stock
Torin 2 50mg
$330.00
In stock
Torin 2 100mg
$490.00
In stock
Torin 2 10mM * 1mL in DMSO
$111.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's Torin 2 has been cited by 1 publications
  • Diane Yang, .et al. , Diabetes, 2021, Oct;70(10):2419-2429 PMID: 34344789
  • Biological Activity
    Discription Torin 2 is a potent and selective mTOR inhibitor (IC50 = 2.1 nM). Displays 800-fold cellular selectivity for mTOR over PI3K (cellular EC50 values are 0.25 and 200 nM for mTOR and PI3K respectively).
    Targets
    Target Value
    Product Information
    Catalog Num A11586
    Formula C24H15F3N4O
    Molecular Weight 432.4
    CAS Number 1223001-51-1
    SMILES C1=CC(=CC(=C1)N2C(=O)C=CC3=CN=C4C=CC(=CC4=C32)C5=CN=C(C=C5)N)C(F)(F)F
    Synonyms Torin2
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 18 mg/mL (41.63 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 5%DMSO+40%PEG300+5%Tween80+50%ddH2O 1.4 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 23.13 mL 115.63 mL 231.27 mL
    0.5 mM 4.63 mL 23.13 mL 46.25 mL
    1 mM 2.31 mL 11.56 mL 23.13 mL
    5 mM 0.46 mL 2.31 mL 4.63 mL
    Useful Calculator

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    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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