Catalog No.
Product Name
Application
Product Information
Citations
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Biochemical Assay Reagent
Phlorizin dihydrate is a biochemical reagent that acts as a specific inhibitor of glucose transporters, primarily SGLT1 and SGLT2. Its key biological activity includes the inhibition of glucose reabsorption in the kidneys, making it valuable for studies in diabetes and renal physiology. Phlorizin dihydrate is commonly used in research applications involving glucose transport mechanisms and metabolic profiling. -
Ca2+ Inducer
D-myo-Inositol-1,3,4,5-tetrakisphosphate potassium acts as a Ca2+ inducer by enhancing extracellular calcium entry via the upregulation of voltage-gated calcium channels. This compound is instrumental in studies related to calcium signaling pathways and is often utilized in investigations of cellular processes influenced by calcium ions. It serves as a valuable reagent for researchers exploring the roles of calcium in various physiological and pathological contexts. -
Active Small Molecule
17α-Hydroxydigitoxigenin is an active small molecule primarily known for its ability to inhibit Na+/K+-ATPase activity. This inhibition plays a crucial role in various physiological processes and has been linked to cardiac and neuroprotective effects. It is relevant for research applications involving ion transport, cellular signaling, and the study of cardiovascular diseases. -
Biochemical Assay Reagent
Digitoxigenin is a biochemical assay reagent primarily used for the study of cardiac glycosides. This compound exhibits significant biological activity, particularly in inhibiting Na+/K+ ATPase, which is crucial for cell membrane potential and ion transport. It is applied in research focusing on cardiac function, cellular signaling, and related pathways in various biological systems. -
Starting CompoundsFor The Synthesis of KV7.2/3 Openers
2,6-Dichloro-3-nitropyridine is a key starting compound in the synthesis of sulfide analogs of Flupirtine, which function as KV7.2/3 channel openers. This compound exhibits potential biological activity relevant to pain research, making it a valuable reagent for studies focused on the modulation of neuronal excitability and analgesic mechanisms. Its utility in the development of KV7.2/3 activators positions it as an important tool in therapeutic research. -
Oct4 Activator
Oct4 inducer-1 is a potent activator of the Oct4 transcription factor, significantly enhancing the expression of Oct4 and Nanog promoters. This compound promotes the formation of induced pluripotent stem cells (iPSCs) and improves the efficiency of cell reprogramming while reducing the overall reprogramming time. It is a valuable tool for research applications in stem cell biology and regenerative medicine. -
OCT4 Inducer
Oct4 inducer-2 is a compound that promotes the expression of endogenous OCT4, facilitating the maintenance and proliferation of human induced pluripotent stem cells (hiPSCs). This inducer is valuable for research applications focused on stem cell biology, regenerative medicine, and anti-aging studies. By enhancing OCT4 levels, Oct4 inducer-2 supports the maintenance of pluripotency, making it an essential tool for scientists investigating cellular reprogramming and differentiation. -
Reserpine Analog
Bishomoreserpine is a reserpine analog that acts primarily as a monoamine transporter inhibitor. It exhibits significant inhibitory activity, impacting neurotransmitter uptake and revealing potential roles in studying neuropharmacology. This compound is useful in research aimed at understanding the mechanisms of neurotransmitter regulation and developing therapeutic strategies for related disorders. -
Amphetamine Derivative
N-Ethyl-3,4-DMA hydrochloride is an amphetamine derivative that primarily targets the monoamine transporters, particularly the serotonin and dopamine transporters. This compound exhibits psychoactive properties and is explored for its potential effects on mood and cognition. Its unique profile makes it a valuable reagent for studies in neuropharmacology and the investigation of amphetamine-like substances. -
Drug Derivative
1-(4-Methylphenyl)-2-(propylamino)propan-1-one hydrochloride is a drug derivative that primarily targets monoamine transporters. This compound exhibits significant biological activity as a stimulant and may influence neurotransmitter release. Its applications in research include investigating the mechanisms of action of psychoactive substances and studying mood disorders. -
Drug Derivative
N-Demethyl methylone hydrochloride is a drug derivative that primarily targets monoamine transporters, including the serotonin and dopamine transporters. This compound exhibits stimulatory effects and is often utilized in research focused on psychoactive substances and their metabolic pathways. Its biological activity is relevant for studies exploring the pharmacological properties of substituted cathinones and their effects on neurotransmitter systems. -
Tropane
Tropacocaine hydrochloride is a tropane derivative that acts primarily as a local anesthetic by blocking sodium channels in neuronal membranes. Its key biological activity includes analgesic effects, making it valuable in pain research and studies of neuronal signaling. Tropacocaine hydrochloride is utilized in investigations of tropane-based compounds and their pharmacological profiles in the context of neurological studies. -
α-Pyrrolidinopropiophenone Derivative
4'-Fluoro-α-pyrrolidinopropiophenone hydrochloride is a derivative of α-Pyrrolidinopropiophenone, primarily acting on the monoamine transporters. This compound exhibits stimulant properties, making it relevant for research in neuropharmacology and the study of addiction mechanisms. Its applications also extend to the exploration of dopamine and norepinephrine reuptake inhibition, aiding in the development of potential therapeutic agents targeting these neurotransmitter systems. -
Amphetamine Derivative
N-Benzyl-3,4-DMA hydrochloride is an amphetamine derivative that primarily targets monoamine transporters. This compound exhibits stimulant properties, making it valuable for research into neurotransmitter regulation and potential therapeutic applications in neuropharmacology. Its structural similarities to other amphetamines enable exploration into their effects on behavior and cognitive function. -
Amphetamine compound
MMDPPO is an amphetamine compound that primarily acts as a monoamine transporter inhibitor. This reagent displays key biological activity by enhancing dopamine and norepinephrine levels in the synaptic cleft, which can influence neurotransmitter release and receptor activation. MMDPPO is useful in research applications related to neuropharmacology, behavioral studies, and the mechanisms underlying stimulant effects. -
Amphetamine
Tosyl-methamphetamine is a potent amphetamine analogue that primarily targets monoamine transporters. It exhibits stimulant properties and is commonly used in research to investigate the effects of amphetamines on neurotransmitter release and behavior. This compound plays a significant role in the study of addiction mechanisms and pharmacological profiling of stimulant drugs. -
6-Iodonordihydrocapsaicin Analogue
CAY10448 is a 6-Iodonordihydrocapsaicin analogue that selectively modulates the transient receptor potential vanilloid 1 (TRPV1) channel. This compound serves as a valuable tool for research into pain pathways and sensory neuron activation. Its ability to interact with TRPV1 makes it useful for studies investigating pain mechanisms, neuroprotective effects, and the modulation of inflammatory responses. -
Amphetamine
4-Chloroethamphetamine hydrochloride is a potent amphetamine analog that primarily targets the monoamine transporters, particularly the norepinephrine and serotonin transporters. This compound exhibits significant stimulant properties, making it relevant for research into neuropharmacology and the mechanisms of substance use disorders. Its structural modifications provide insights into the development of new therapeutic strategies for various neurological and psychiatric conditions. -
Drug Derivative Control
3-Methylbuphedrone hydrochloride is a methylated derivative of Buphedrone, primarily targeting monoamine transporters. This compound exhibits stimulant properties and has been studied for its effects on dopaminergic and serotonergic systems. It is relevant in research related to drug control, psychoactive substances, and their pharmacological profiles. -
Drug Derivative
3,4-DMMC hydrochloride is a derivative of Mephedrone, primarily targeting monoamine transporters including the serotonin and dopamine transporters. It has demonstrated psychostimulant properties, which makes it a valuable compound for studying drug-related behavior and neuropharmacology. Its application in research includes investigations into the mechanisms of addiction and mood regulation. -
Drug Derivative
PCA50941 is a 1,4-dihydropyridine derivative that primarily targets calcium channels. This compound exhibits potential biological activity in the modulation of cardiovascular function, making it useful for research in cardiovascular disease mechanisms. Its application extends to the exploration of novel therapeutic strategies in the treatment of hypertension and related cardiovascular conditions. -
Amphetamine
3-Methoxymethamphetamine hydrochloride is an analog of amphetamine, primarily targeting monoamine transporters. This compound exhibits stimulant properties and is utilized in the study of neuropharmacology, particularly in understanding the mechanisms of action associated with amphetamines. Its application in research can provide insights into drug addiction, behavioral studies, and the effects of stimulant drugs on the central nervous system. -
Methylenedioxy Pyrovalerone Analog
3,4-Dimethoxy-α-Pyrrolidinopentiophenone hydrochloride is a structural analog of Methylenedioxy Pyrovalerone primarily targeting monoamine transporters. This compound exhibits stimulant properties and is utilized in research for studying the effects on neurotransmitter uptake and release. Its unique properties make it a valuable reagent for investigating mechanisms of action in the fields of neuropharmacology and psychopharmacological studies. -
Drug Derivative
Piridocaine hydrochloride is a derivative of ortho-aminobenzoic acid and functions as a local anesthetic agent. It primarily acts by blocking sodium channels, thereby inhibiting action potential propagation in excitable membranes. This compound plays a significant role in research related to pain management, neuromuscular function, and pharmacological studies of anesthetics. Its unique pharmacological profile makes it a valuable tool for investigating local anesthetic mechanisms and applications in various biological systems. -
Drug Impurity
Ranolazine impurity 10 is a chemical impurity associated with the cardiovascular drug Ranolazine, which primarily targets sodium channels. This impurity is significant for analytical and quality control purposes in pharmaceutical research and development, aiding in the assessment of the drug's purity and safety profile. Its identification and quantification are critical for compliance with regulatory standards in the drug manufacturing process. -
Phosphate Ester Prodrug
Fosphenytoin is a phosphate ester prodrug that acts as a rapid-acting antiepileptic agent, primarily targeting sodium channels to stabilize neuronal membranes. It demonstrates significant efficacy in the acute management of seizures, particularly in emergency settings. Fosphenytoin's formulation allows for convenient intravenous and intramuscular administration, reducing the risk of local adverse reactions and facilitating effective treatment in acute care situations. -
Drug Impurity
Fluralaner impurity 2 is a drug impurity associated with the insecticide Fluralaner, which primarily targets the GABA and glutamate-gated chloride channels in arthropods. This compound serves as a valuable reference standard for analytical applications in quality control and method development related to Fluralaner synthesis and formulation. Its characterization aids in understanding the impurities' impact on pharmacological efficacy and safety profiles in research and regulatory contexts. -
Photolabile Proton Donor
DMNB (6-Nitroveratraldehyde) functions as a photolabile proton donor, releasing acidic species upon excitation at a wavelength of 405 nm. It is employed in the synthesis of no-carrier-added 6-[18F]fluoro-L-DOPA (6-FDOPA) and is useful for preparing o-nitroaryl-bis(5-methylfur-2-yl)methanes and alpha-asarone. Additionally, DMNB is relevant in studies involving the non-homologous end joining (NHEJ) pathway for DNA double-strand break repair and is applicable in PET imaging of the dopaminergic system. -
Drug Impurity
Pregabalin impurity 3 is a recognized impurity associated with the drug Pregabalin, which primarily targets voltage-gated calcium channels. This compound may play a role in understanding the metabolic pathways and degradation processes of Pregabalin. Research applications of Pregabalin impurity 3 include method development for impurity analysis in pharmaceuticals and exploring potential interactions that could affect drug safety and efficacy. -
Stable Isotope
Digitoxigenin-21,23,23-d3 is a deuterium-labeled derivative of Digitoxigenin, serving as a stable isotope for research applications. This compound is primarily important for the synthesis of cardiac glycosides used in the treatment of heart failure and arrhythmias. By inhibiting the sodium-potassium ATPase pump, Digitoxigenin enhances cardiac contraction efficiency and force, making it a critical component in cardiovascular research and drug development. -
Biochemical Assay Reagents
6-FAM-AEEAc-Stichodactyla helianthus Neurotoxin (ShK) is a fluorescent-labeled polypeptide that primarily targets voltage-gated potassium channels. This reagent exhibits potent inhibitory activity on ion channel function, making it valuable for biochemical assays focused on channel pharmacology and neurobiology. Its applications extend to studies investigating ion channel modulation and neurotoxin interactions in cellular models. -
Biochemical Assay Reagent
08:0 PI(4,5)P2 ammonium is a biochemical assay reagent that targets lipid signaling pathways. Its primary application involves probing the binding site at the transient receptor potential vanilloid 4 (TRPV4) N-terminus. This compound facilitates the study of cellular mechanisms influenced by phosphoinositides, contributing valuable insights into TRPV4-related functions in various physiological contexts. -
Biochemical Assay Reagent
Florbenazine is a diagnostic imaging agent that selectively targets the vesicular monoamine transporter 2 (VMAT2) in the central nervous system. The fluorine-18 labeled derivative is utilized in positron emission tomography (PET) scanning to assess neuromodulatory functions. Research has demonstrated a significant biodistribution profile in mice, with a high striatum-to-cerebellum ratio, supporting its application in the diagnostic investigation of neurodegenerative disorders, such as dementia with Lewy bodies and Parkinson’s disease. -
Drug Derivative
(R)-Norverapamil is a pharmacologically active derivative of verapamil, primarily targeting L-type calcium channels. It exhibits significant cardiovascular effects, including the modulation of heart rate and contractility. This compound is commonly utilized in research focused on cardiac pharmacology, calcium channel modulation, and the investigation of cardiovascular diseases. -
α-PVP Analog
α-Dimethylaminopentiophenone hydrochloride is an analog of α-Pyrrolidinopentiophenone (α-PVP), characterized by the substitution of a dimethylamino group in place of the pyrrolidine moiety. This compound exhibits stimulant properties and has been used in research to investigate its effects on monoamine transporters, contributing to the understanding of its neuropharmacological profile. Its utility in exploring mechanisms underlying addiction and substance use disorders makes it a valuable tool for scientific studies in pharmacology and toxicology. -
Biochemical Reagent
Glycopyramide is a sulfonylurea compound that primarily targets and inhibits the ATP-sensitive potassium channels in pancreatic beta cells. This inhibition promotes insulin secretion, making it relevant in the study of diabetes and glucose metabolism. It can be utilized in biochemical research to explore mechanisms of insulin release and the regulation of blood glucose levels. -
Biochemical Assay Reagents
Lifarizine is an organic compound that targets histamine H1 receptors and calcium channels, playing a role in modulating neurotransmitter release. Its primary applications in biochemical assays include studying cellular signaling pathways and exploring the pharmacological effects of antihistamines. Lifarizine is valuable in life science research for investigating potential therapeutic effects and mechanisms of action in various biological contexts. -
Drug Impurity
N-(2,6-dimethylphenyl)-2-(ethyl(methyl)amino)acetamide hydrochloride is a recognized impurity associated with the sodium channel inhibitor Lidocaine. This compound may serve as a reference standard for quality control and analytical studies within pharmacological research. It can aid in the assessment of drug purity and the validation of analytical methods used in drug development and manufacturing processes. -
Drug Impurity
Amlodipine impurity 3 is a specific impurity associated with the calcium channel blocker Amlodipine. This compound is significant for drug quality assessments and regulatory compliance in pharmaceutical research. It is utilized in the development and validation of analytical methods for the quantification and characterization of impurities in drug formulations. -
Alkaloid
Lipoaconitine is a natural alkaloid known for its regulatory effects on voltage-gated sodium channels. It exhibits notable biological activity, including analgesic and anti-inflammatory properties, making it a valuable tool for research in pain management and neurobiology. Its unique pharmacological profile provides insights into the mechanisms underlying sodium channel modulation and potential therapeutic applications. -
Drug Derivative
N-Methoxy mephedrone hydrochloride is a derivative of mephedrone, primarily targeting monoamine transporters. This compound exhibits stimulant properties and can influence serotonin and dopamine release, making it valuable for research in neuropharmacology. Its applications extend to studies investigating psychostimulant effects and the development of new therapeutic strategies for mood disorders. -
Drug Derivative
4-Methyl-α-pyrrolidinoisohexanophenone hydrochloride is a drug derivative that primarily targets the monoamine transporter system. It exhibits stimulant and psychoactive properties, making it a valuable tool in neuropharmacological research. This compound may be utilized in studies investigating the mechanisms of drug action and the effects of novel psychoactive substances on neurotransmitter dynamics. -
Brassinosteroid
24-Epicastasterone is a bioactive brassinosteroid that functions as a ligand for the ABCB1 and ABCB19 transporters in Arabidopsis thaliana. Its primary mechanisms include stimulating ATPase activity in ABCB19 and promoting ATP hydrolysis in ABCB1, facilitating the efflux of compounds from plant cells. Additionally, 24-Epicastasterone enhances the activities of catalase and guaiacol peroxidase in wheat roots, thereby mitigating heat-induced lipid peroxidation and improving heat tolerance in common wheat seedlings. This compound is valuable for research into plant stress responses and hormonal signaling pathways. -
Drug Derivative
Flumethrin is a synthetic pyrethroid insecticide that acts primarily by modulating sodium channels in the nervous system of insects, leading to paralysis and death. This compound exhibits potent insecticidal activity against a wide range of pests, making it valuable in agricultural and veterinary applications. Flumethrin is primarily utilized in research settings to study insect behavior, insecticide resistance, and neurological pathways relevant to pest control strategies. -
Drug Derivative
N-Acetyl-3,4-MDMC is a drug derivative structurally related to 3,4-methylenedioxymethcathinone. This compound has been investigated for its psychoactive properties and potential interactions with monoamine transporters, particularly serotonin and dopamine receptors. Research applications include studies on its effects on neural activity and behavioral responses in various models of neurotransmission. -
Tocainid Analog
2-Amino-N-phenylpropanamide hydrochloride is an analog of Tocainid, an antiarrhythmic agent that modulates cardiac sodium channels. This compound exhibits potential in cardiac research by influencing ion channel function and demonstrating effects on arrhythmia management. It serves as a valuable tool for studies related to cardiovascular pharmacology and the development of novel antiarrhythmic therapies. -
Drug Derivative
3-Bromomethcathinone hydrochloride is a drug derivative targeting monoamine transporters. It exhibits stimulant properties and has been studied for its effects on catecholamine and serotonin release. This compound is utilized in research related to neuropharmacology and the exploration of synthetic cathinones. -
Dehydro Amlodipine Derivatives
Dehydro amlodipine fumarate is a derivative of dehydro amlodipine, primarily formed through the forced degradation of dehydro amlodipine under oxidative and acidic conditions. This compound is utilized in chemical research to study the stability and degradation pathways of dihydropyridine calcium channel blockers. It serves as a crucial intermediate in understanding the pharmacological properties and metabolic fate of calcium channel antagonists in various biological systems. -
Drug Derivative
Leucinocaine is a drug derivative that acts as a local anesthetic by inhibiting sodium channel activity, thereby blocking nerve impulse conduction. Its primary biological activity involves pain relief in localized areas, making it useful for various clinical and research applications in pain management and anesthetic studies. This compound can also serve as a valuable tool in neuropharmacological research and the development of new analgesic agents. -
Neuroactive Compound
Para-fluoro methylaminorex is a neuroactive compound that primarily interacts with monoamine transporters. This compound exhibits stimulant properties and has been utilized in research to explore mechanisms underlying neuropharmacology and psychoactive effects. Its unique structure allows for the investigation of its impact on neurotransmitter systems, contributing to the understanding of CNS function and disorder.
