Tubastatin A HCl

Catalog No.: A11042
HDAC6 inhibitor
Tubastatin A is a potent and selective HDAC6 inhibitor with IC50 of 15 nM in a cell-free assay. It is selective against all the other isozymes (1000-fold) except HDAC8 (57-fold).
Grouped product items
Product Name Price Stock Qty
Tubastatin A HCl 10mg
$60.00
In stock
Tubastatin A HCl 25mg
$80.00
In stock
Tubastatin A HCl 50mg
$90.00
In stock
Tubastatin A HCl 100mg
$150.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's Tubastatin A HCl has been cited by 2 publications
  • Isin Cakir, .et al. , Nat Metab, 2022, Jan;4(1):44-59 PMID: 35039672
  • Isin Cakir, .et al. , Elife, 2022, Mar 24 PMID: 35323110
  • Biological Activity
    Discription Tubastatin A is a potent and selective HDAC6 inhibitor with IC50 of 15 nM in a cell-free assay. It is selective against all the other isozymes (1000-fold) except HDAC8 (57-fold).
    Targets
    Target Value
    Product Information
    Catalog Num A11042
    Formula C20H21N3O2.HCl
    Molecular Weight 371.9
    CAS Number 1310693-92-5, 1239262-52-2
    SMILES CN1CCC2=C(C1)C3=CC=CC=C3N2CC4=CC=C(C=C4)C(=O)NO.Cl
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 67 mg/mL (180.17 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 5%DMSO+40%PEG300+5%Tween80+50%ddH2O 5.2 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 26.89 mL 134.44 mL 268.89 mL
    0.5 mM 5.38 mL 26.89 mL 53.78 mL
    1 mM 2.69 mL 13.44 mL 26.89 mL
    5 mM 0.54 mL 2.69 mL 5.38 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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