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$0.00 - Hassan GS, .et al. Anti-hepatitis-C virus activity and QSAR study of certain thiazolidinone and thiazolotriazine derivatives as potential NS5B polymerase inhibitors, Eur J Med Chem, 2019, Oct 1;184:111747 PMID: 31604164
Biological Activity
VCH-759 is a non-nucleoside inhibitor of HCV RNA-dependent polymerase with sub-micromolar IC50 values versus genotype 1a/1b replicons.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.57 mL | 107.86 mL | 215.72 mL |
| 0.5 mM | 4.31 mL | 21.57 mL | 43.14 mL |
| 1 mM | 2.16 mL | 10.79 mL | 21.57 mL |
| 5 mM | 0.43 mL | 2.16 mL | 4.31 mL |
*The above data is based on the productmolecular weight 463.56. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A15479 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 463.56 |
| Formula | C25H30NNaO4S |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 1001913-13-8 |
| Synonyms | VCH759, VCH 759 |
| SMILES | CC1CCC(CC1)C(=O)N(C2CCC(CC2)O)C3=C(SC(=C3)C4=CC=CC=C4)C(=O)[O-].[Na+] |
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