VE-821

Catalog No.: A11605
ATM/ATR inhibitor
VE-821 is a potent and selective inhibitor of protein kinase ATR.
Grouped product items
Product Name Price Stock Qty
VE-821 10mg
$77.00
In stock
VE-821 25mg
$154.00
In stock
VE-821 50mg
$231.00
In stock
VE-821 10mM * 1mL in DMSO
$80.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's VE-821 has been cited by 6 publications
  • Atsushi Saito, .et al. , Cell Rep, 2023, May 30;42(5):112479 PMID: 37178686
  • Mitsuru Sasaki-Honda, .et al. , Hum Mol Genet, 2018, Dec 1; 27(23): 4024-4035 PMID: 30107443
  • Kim J, .et al. , Mol Cell, 2018, Jan 4;69(1):36-47.e7 PMID: 29249653
  • Antonio Postigo, .et al. , Cell Rep, 2017, May 2; 19(5): 1022-1032 PMID: 28467896
  • Nnennaya Kanu, .et al. , Genome Biol, 2016, 17: 185 PMID: 27634334
  • Carolyn Botting, .et al. , Virol J, 2016, 13: 15 PMID: 26817608
  • Biological Activity
    Discription VE-821 is a potent and selective inhibitor of protein kinase ATR.
    Targets
    Target Value
    Product Information
    Catalog Num A11605
    Formula C18H16N4O3S
    Molecular Weight 368.4
    CAS Number 1232410-49-9
    SMILES CS(=O)(=O)C1=CC=C(C=C1)C2=CN=C(C(=N2)C(=O)NC3=CC=CC=C3)N
    Synonyms VE821
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 65 mg/mL (176.43 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 30% PEG400+0.5% Tween80+5% propylene glycol 28 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 27.14 mL 135.72 mL 271.44 mL
    0.5 mM 5.43 mL 27.14 mL 54.29 mL
    1 mM 2.71 mL 13.57 mL 27.14 mL
    5 mM 0.54 mL 2.71 mL 5.43 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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