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VE-821

Catalog No.: A11605
ATM/ATR inhibitor
Adooq's VE-821 has been cited by 6 publications
VE-821 is a potent and selective inhibitor of protein kinase ATR.
VE-821
Grouped product items
Size Price Stock Qty
2mg
$25.00
In stock
5mg
$40.00
In stock
10mg
$65.00
In stock
25mg
$120.00
In stock
50mg
$190.00
In stock
100mg
$360.00
In stock
10mM * 1mL in DMSO
$45.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's VE-821 has been cited by 6 publications
  • Atsushi Saito, .et al. , Cell Rep, 2023, May 30;42(5):112479 PMID: 37178686
  • Mitsuru Sasaki-Honda, .et al. , Hum Mol Genet, 2018, Dec 1; 27(23): 4024-4035 PMID: 30107443
  • Kim J, .et al. , Mol Cell, 2018, Jan 4;69(1):36-47.e7 PMID: 29249653
  • Antonio Postigo, .et al. , Cell Rep, 2017, May 2; 19(5): 1022-1032 PMID: 28467896
  • Nnennaya Kanu, .et al. , Genome Biol, 2016, 17: 185 PMID: 27634334
  • Carolyn Botting, .et al. , Virol J, 2016, 13: 15 PMID: 26817608
    • Biological Activity
    Discription VE-821 is a potent and selective inhibitor of protein kinase ATR.
    Targets
    Target Value
    Cell Research
    Cell Line Type Value Description References
    Product Information
    Catalog Num A11605
    Formula C18H16N4O3S
    Molecular Weight 368.4
    CAS Number 1232410-49-9
    SMILES CS(=O)(=O)C1=CC=C(C=C1)C2=CN=C(C(=N2)C(=O)NC3=CC=CC=C3)N
    Synonyms VE821
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
    Solubility
    In vitro (25°C) DMSO 65 mg/mL (176.43 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 30% PEG400+0.5% Tween80+5% propylene glycol 28 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 27.14 mL 135.72 mL 271.44 mL
    0.5 mM 5.43 mL 27.14 mL 54.29 mL
    1 mM 2.71 mL 13.57 mL 27.14 mL
    5 mM 0.54 mL 2.71 mL 5.43 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

      Concentration

      Volume

      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

    • C1

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      C2

      V2

    • Calculator Reset
    PI3K/Akt/mTOR > ATM/ATR
    DNA Damage > ATM/ATR
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