Vorinostat (SAHA)

Vorinostat is an inhibitor of HDACs, inhibiting deacetylation and leading to an accumulation of both hyperacetylated histones and transcription factors.
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Size Price Stock Qty
200mg
$35.00
In stock
500mg
$70.00
In stock
1g
$95.00
In stock
5g
$435.00
In stock
10mM * 1mL in DMSO
$45.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's Vorinostat (SAHA) has been cited by 7 publications
  • Masahiro Yamada, .et al. , Int J Hematol, 2024, Sep;120(3):325-336 PMID: 38954186
  • Amy E Neely, .et al. , Commun Biol, 2023, Jun 23;6(1):664 PMID: 37353594
  • Ting-Yu Chang, .et al. , Biomed Pharmacother, 2021, Jun;138:111485 PMID: 33740521
  • David Diaz-Carballo, .et al. , Commun Biol, 2021, Mar 3;4(1):276 PMID: 33658617
  • Arshdeep Singh, .et al. , Eur J Med Chem, 2021, Apr 5;215:113169 PMID: 33588178
  • Shariful Islam, .et al. , Blood Adv, 2020, 4(20): 5297-5310 PMID: 33108458
  • Giovanni Bocci, .et al. , ACS Pharmacol Transl Sci, 2020, Oct 14
  • Biological Activity
    Discription Vorinostat is an inhibitor of HDACs, inhibiting deacetylation and leading to an accumulation of both hyperacetylated histones and transcription factors.
    Targets
    Target Value
    Cell Research
    Cell Line Type Value Description References
    Product Information
    Catalog Num A10979
    Formula C14H20N2O3
    Molecular Weight 264.3
    CAS Number 149647-78-9
    SMILES C1=CC=C(C=C1)NC(=O)CCCCCCC(=O)NO
    Synonyms Zolinza, MK-0683
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 49 mg/mL (185.39 mM)
    Water Insoluble
    Ethanol 3 mg/mL (11.35 mM)
    In vivo 2% DMSO+30% PEG 300+5% Tween 80+ddH2O 4 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 37.84 mL 189.18 mL 378.36 mL
    0.5 mM 7.57 mL 37.84 mL 75.67 mL
    1 mM 3.78 mL 18.92 mL 37.84 mL
    5 mM 0.76 mL 3.78 mL 7.57 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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