Vorinostat (SAHA)

Catalog No.: A10979

HDAC inhibitor

Vorinostat (SAHA)

Vorinostat (SAHA) Chemical Structure

CAS NO. 149647-78-9

Vorinostat is an inhibitor of HDACs, inhibiting deacetylation and leading to an accumulation of both hyperacetylated histones and transcription factors.

Availability: In stock

Package Price Qty
200 mg

Regular Price: $45.00

Special Price $36.00

500 mg

Regular Price: $95.00

Special Price $76.00

10mM * 1mL in DMSO
$60.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Details

Vorinostat is an inhibitor of HDACs, inhibiting deacetylation and leading to an accumulation of both hyperacetylated histones and transcription factors.
Targets
HDAC (Cell-free assay)
~10 nM
In vitro (25°C) DMSO 53 mg/mL (200.52 mM)
Water <1 mg/mL (<1 mM)
Ethanol 3 mg/mL (11.35 mM)
In vivo 2% DMSO, 40% PEG 300, 5% propylene glycol, 1% Tween 80 5 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 37.84 mL 189.18 mL 378.36 mL
0.5 mM 7.57 mL 37.84 mL 75.67 mL
1 mM 3.78 mL 18.92 mL 37.84 mL
5 mM 0.76 mL 3.78 mL 7.57 mL

*The above data is based on the productmolecular weight 264.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

Catalog Num A10979
Actions Inhibitor
M. Wt 264.3
Formula C14H20N2O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 149647-78-9
Synonyms Zolinza, MK-0683
SMILES C1=CC=C(C=C1)NC(=O)CCCCCCC(=O)NO

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