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Vorinostat (SAHA)


HDAC inhibitor

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Catalog No. A10979

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Vorinostat 200mg A10979-200

Regular Price: $45.00

Special Price: $40.50

Vorinostat 500mg A10979-500

Regular Price: $95.00

Special Price: $85.50

Vorinostat (SAHA) 10mM * 1mL in DMSO A10979-10mM-D

Regular Price: $60.00

Special Price: $54.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Vorinostat is an inhibitor of HDACs, inhibiting deacetylation and leading to an accumulation of both hyperacetylated histones and transcription factors.

Vorinostat (SAHA)

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Chemical Information

Catalog Num A10979
Actions Inhibitor
M. Wt 264.3
Formula C14H20N2O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 149647-78-9
Synonyms Zolinza, MK-0683

Biological Activity

Vorinostat is an inhibitor of HDACs, inhibiting deacetylation and leading to an accumulation of both hyperacetylated histones and transcription factors.
HDAC (Cell-free assay)
~10 nM


Solubility (25°C) * In vitro DMSO 53 mg/mL (200.52 mM)
Water <1 mg/mL (<1 mM)
Ethanol 3 mg/mL (11.35 mM)
In vivo 2% DMSO, 40% PEG 300, 5% propylene glycol, 1% Tween 80 5 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 37.84 mL 189.18 mL 378.36mL
0.5 mM 7.57 mL 37.84 mL 75.67 mL
1 mM 3.78 mL 18.92 mL 37.84 mL
5 mM 0.76 mL 3.78 mL 7.57 mL

*The above data is based on the productmolecular weight 264.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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