Giovanni Bocci, .et al. , ACS Pharmacol Transl Sci, 2020, Oct 14
Vorinostat is an inhibitor of HDACs, inhibiting deacetylation and leading to an accumulation of both hyperacetylated histones and transcription factors.
Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
In vitro (25°C)
49 mg/mL (185.39 mM)
3 mg/mL (11.35 mM)
2% DMSO+30% PEG 300+5% Tween 80+ddH2O
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.