ZG297 is an agonist of Staphylococcus aureus ClpP (SaClpP) with an EC50 of 0.26 μM. This compound effectively degrades SaFtsZ and inhibits bacterial cell division, demonstrating potent antistaphylococcal activity against S. aureus 8325-4 and MRSA strains, with a minimum inhibitory concentration (MIC) ranging from 0.063 to 256 μg/mL. Additionally, ZG297 has shown efficacy in anti-infectious applications in mouse models, making it a valuable tool for research in antibiotic development.
ZG297 is an agonist of Staphylococcus aureus ClpP (SaClpP) with an EC50 of 0.26 μM. This compound effectively degrades SaFtsZ and inhibits bacterial cell division, demonstrating potent antistaphylococcal activity against S. aureus 8325-4 and MRSA strains, with a minimum inhibitory concentration (MIC) ranging from 0.063 to 256 μg/mL. Additionally, ZG297 has shown efficacy in anti-infectious applications in mouse models, making it a valuable tool for research in antibiotic development.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
