Name: Cyclizine
Brand: Adooq Bioscience
SKU: A22699
Rating: 5 (288 reviews)

Catalog No.

Product Name

Application

Product Information

Citations

A10891

Tasosartan

Angiotensin II receptor antagonist

Tasosartan is an angiotensin II receptor antagonist.

Quick View
A10962

Valsartan

angiotensin II receptor antagonist

Valsartan (CGP-48933) is an angiotensin II receptor antagonist for the treatment of high blood pressure and heart failure.

Quick View
A11004

Zafirlukast

LTD4 receptor antagonist

Zafirlukast is a potent orally active leukotriene D4 (LTD4) receptor antagonist.

Quick View
A11008

Ziprasidone hydrochloride monohydrate

5-HT (serotonin) and dopamine receptor antagonist

Ziprasidone hydrochloride monohydrate (CP 88059 hydrochloride monohydrate) is a combined 5-HT (serotonin) and dopamine receptor antagonist which exhibits potent effects of antipsychotic activity.

Quick View
A11048

LY2940680 (Taladegib)

SMO Antagonist

LY2940680 has been shown to affect a cancer cell signaling pathway initiated by the Hedgehog (Hh) protein.

Quick View
A11069

Fosaprepitant dimeglumine

neurokinin-1 receptor antagonist

Fosaprepitant is a selective neurokinin-1 (NK-1) receptor antagonist.

Quick View
A11106

LY310762

5-HT Receptor antagonist

LY310762 is a 5-HT1D-preferring receptor antagonist (EC50 = 31 nM).

Quick View
A11117

Ciproxifan maleate

H3-receptor antagonist

Ciproxifan maleate is a potent, selective H3 histamine receptor antagonist.

Quick View
A23883

R715

bradykinin B1 receptor antagonist

R715 is a selective bradykinin B1 receptor antagonist. R715 significantly attenuates the hyperalgesic effect developed in Streptozotocin-diabetic mice.

Quick View
A22078

Exendin(9-39) amide (Avexitide)

GLP-1 antagonist

Avexitide (Exendin (9-39)) is a specific and competitive GLP-1 receptor antagonist.

Quick View
A22551

Atosiban acetate

vasopressin/oxytocin receptor antagonist

Atosiban acetate (RW22164 acetate;RWJ22164 acetate) is a nonapeptide competitive vasopressin/oxytocin receptor antagonist, and is a desamino-oxytocin analogue. Atosiban is the main tocolytic agent and has the potential for spontaneous preterm labor research.

Quick View
A22734

SHU 9119

MC3/4R Antagonist

SHU 9119 is a potent human melanocortin 3 and 4 receptors (MC3/4R) antagonist and a partial MC5R agonist; with IC50 values of 0.23, 0.06, and 0.09 nM for human MC3R, MC4R and MC5R, respectively.

Quick View
A23113

Antagonist G

vasopressin antagonist

Antagonist G is a potent vasopressin antagonist. Antagonist G is also a weak antagonist of GRP and Bradykinin. Antagonist G induces AP-1 transcription and sensitizes cells to chemotherapy.

Quick View
A23120

GR 64349

NK2 receptor peptide antagonist

GR 64349 is a potent and highly selective NK2 receptor peptide antagonist, with an EC50 of 3.7 nM in rat colon. GR 64349 exhibits selectivity >1000 and >300-fold with respect to NK1 and NK3 receptors, respectively.

Quick View
A23191

DOTA-JR11

somatostatin receptor 2 antagonist

DOTA-JR11 is a somatostatin receptor 2 (SSTR2) antagonist. DOTA-JR11 can be labeled by 68Ga, used for paired imaging in neuroendocrine tumors (NETs) research.

Quick View
A22563

Luzindole

MT1/MT2 antagonist

Luzindole, also known as N-0774, and N-acetyl-2-benzyltryptamine, is a melatonin receptor antagonist that preferentially targets MT1B over MT1A (Ki values are = 10-27 and 158-513 nM, respectively).

Quick View
A22564

LM11A-31 HCl

p75NTR modulator/proNGF antagonist

LM11A-31 is a small-molecule p75NTR modulator and proNGF antagonist.

Quick View
A22583

JTE-013

S1P2 antagonist

JTE-013 is a potent and specific S1P2 (Sphingosine-1-Phosphate 2; EDG-5) antagonist. JTE-013 inhibits the specific binding of radiolabeled S1P to human and rat S1P2 with IC50s of 17 nM and 22 nM, respectively.

Quick View
A22592

SCH-23390 maleate

dopamine D1-like receptor antagonist

SCH-23390 maleate (R-(+)-SCH-23390 maleate) is a potent and selective dopamine D1-like receptor antagonist with Kis of 0.2 nM and 0.3 nM for the D1 and D5 receptor, respectively.

Quick View
A22609

EMD-66684 potassium salt

angiotensin II receptor antagonist

EMD-66684 is a non-peptide angiotensin II receptor antagonist.

Quick View
A22629

CPCCOEt

mGluR1b antagonist

CPCCOEt is a low affinity, selective, non-competitive antagonist of the metabotropic glutamate receptor subtype mGluR1b.

Quick View
A22631

NPS2390

group I mGlu antagonist

NPS2390 is a group I mGlu antagonist. It displays noncompetitive antagonist activity at both mGlu1 and mGlu5 receptors. NPS2390 is thought to act on a site separate from the glutamate binding pocket.

Quick View
A22637

Talinolol

Beta1-Adrenergic receptor antagonist

Talinolol is a beta(1)-adrenergic receptor antagonist and a probe drug for P-glycoprotein (P-gp) activity in humans.

Quick View
A22638

Betahistine EP Impurity C

histamine H1 receptor agonist and H3 receptor antagonist

Betahistine EP Impurity C (NSC19005) is an impurity of Betahistine. Betahistine is a potent, orally active and well-tolerated histamine H1 receptor agonist and H3 receptor antagonist used for the study of rheumatoid arthritis (RA).

Quick View
A22665

DL 071-IT hydrochloride

beta-adrenoceptor antagonist

DL 071-IT is a potent non-selective beta-adrenoceptor antagonist. .

Quick View
A22679

Etrumadenant (AB928)

adenosine receptor antagonist

AB928 is an orally bioavailable, selective dual adenosine receptor (A2aR/A2bR) antagonist. AB928 relieves adenosine-mediated immune suppression. AB928 has immunomodulatory and antitumor activities.

Quick View
A22699

Cyclizine

antagonist of histamine H1

Cyclizine is an antagonist of histamine H1. Cyclizine is an antihistamine drug that can be used to treat nausea, vomiting and dizziness associated with motion sickness, vertigo and post-operatively following administration of general anaesthesia and opioids.

Quick View

GPCR/G Protein