Catalog No.: A11004

LTD4 receptor antagonist


Zafirlukast Chemical Structure

CAS NO. 107753-78-6

Zafirlukast is a potent orally active leukotriene D4 (LTD4) receptor antagonist.

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Biological Activity

Zafirlukast is a potent orally active leukotriene D4 (LTD4) receptor antagonist.
In vitro (25°C) DMSO 99 mg/mL (171.96 mM)
Water Insoluble
Ethanol Insoluble
In vivo 4% DMSO+30% PEG 300+5% Tween 80+ddH2O 19 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.37 mL 86.85 mL 173.71 mL
0.5 mM 3.47 mL 17.37 mL 34.74 mL
1 mM 1.74 mL 8.69 mL 17.37 mL
5 mM 0.35 mL 1.74 mL 3.47 mL

*The above data is based on the productmolecular weight 575.68. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11004
Actions Antagonist
CAS No. 107753-78-6
Formula C31H33N3O6S
M. Wt 575.68
Purity >98%
Synonyms ICI 204219, ICI-204219, ICI204219

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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