LY2940680 (Taladegib)

Catalog No.: A11048

SMO Antagonist

LY2940680 (Taladegib)

LY2940680 (Taladegib) Chemical Structure

CAS NO. 1258861-20-9

LY2940680 has been shown to affect a cancer cell signaling pathway initiated by the Hedgehog (Hh) protein.

Availability: In stock

Package Price Qty
5 mg
$99.00
10 mg
$175.00
50 mg
$490.00
100 mg
$850.00
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Biological Activity

LY2940680 has been shown to affect a cancer cell signaling pathway initiated by the Hedgehog (Hh) protein.
Targets
Smoothened
In vitro DMSO Warmed: 4 mg/mL (7.8 mM)
Water Insoluble
Ethanol 2 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.51 mL 97.56 mL 195.12 mL
0.5 mM 3.9 mL 19.51 mL 39.02 mL
1 mM 1.95 mL 9.76 mL 19.51 mL
5 mM 0.39 mL 1.95 mL 3.9 mL

*The above data is based on the productmolecular weight 512.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11048
Actions Antagonist
CAS No. 1258861-20-9
Formula C26H24F4N6O
M. Wt 512.5
Purity >98%
Synonyms LY-2940680
SMILES CN1C(=CC=N1)C2=NN=C(C3=CC=CC=C32)N4CCC(CC4)N(C)C(=O)C5=C(C=C(C=C5)F)C(F)(F)F
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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