Fosaprepitant dimeglumine

Catalog No.: A11069

neurokinin-1 receptor antagonist

Fosaprepitant dimeglumine Chemical Structure

CAS NO. 265121-04-8

Fosaprepitant is a selective neurokinin-1 (NK-1) receptor antagonist.

Availability: In stock

Package Price Qty
5 mg
$80.00
10 mg
$140.00
25 mg
$260.00
10mM * 1mL in DMSO
$220.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Fosaprepitant is a selective neurokinin-1 (NK-1) receptor antagonist.
Targets
NK-1 receptor
In vitro DMSO 201 mg/mL (200.03 mM)
Water 135 mg/mL (134.35 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 9.95 mL 49.76 mL 99.52 mL
0.5 mM 1.99 mL 9.95 mL 19.9 mL
1 mM 1 mL 4.98 mL 9.95 mL
5 mM 0.2 mL 1 mL 1.99 mL

*The above data is based on the productmolecular weight 1004.84. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11069
Actions Antagonist
M. Wt 1004.84
Formula C37H56F7N6O16P
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 265121-04-8
Synonyms MK 0517
SMILES C[[email protected]](C1=CC(=CC(=C1)C(F)(F)F)C(F)(F)F)O[[email protected]@H]2[[email protected]@H](N(CCO2)CC3=NC(=O)N(N3)P(=O)(O)O)C4=CC=C(C=C4)F.CNC[[email protected]@H]([[email protected]]([[email protected]@H]([[email protected]@H](CO)O)O)O)O.CNC[[email protected]@H]([[email protected]]([[email protected]@H]([[email protected]@H](CO)O)O)O)O

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