AVN-944

Catalog No.: A13652
IMPDH inhibitor

AVN-944 (also known as VX-944) serves as an effective oral inhibitor, specifically targeting and inhibiting IMPDH (inosine monophosphate dehydrogenase). This enzyme plays a crucial role as a rate-limiting factor in the synthesis of guanine nucleotides from scratch. Additionally, AVN-944 acts against the synthesis of RNA in arenaviruses, effectively preventing arenavirus infections. Demonstrating a wide spectrum of anti-cancer properties, AVN-944 is utilized in research related to multiple myeloma (MM) and acute myeloid leukemia (AML).

Grouped product items
Product Name Price Stock Qty
AVN-944 5mg
$100.00
In stock
AVN-944 10mg
$180.00
In stock
AVN-944 25mg
$320.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500

Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's AVN-944 has been cited by 4 publications
  • Kevin Chiem, .et al. , Microbiol Spectr, 2023, Aug 17;11(4):e0474522 PMID: PMC10434227
  • Desarey Morales Vasquez, .et al. , Viruses, 2020, Sep; 12(9): 1041 PMID: 32961956
  • Park JG, .et al. , J Virol, 2020, Mar 17;94(7) PMID: 31941776
  • Dunham EC, .et al. , Antiviral Res, 2018, Sep;157:140-150 PMID: 30031760
  • Biological Activity
    Discription

    AVN-944 (also known as VX-944) serves as an effective oral inhibitor, specifically targeting and inhibiting IMPDH (inosine monophosphate dehydrogenase). This enzyme plays a crucial role as a rate-limiting factor in the synthesis of guanine nucleotides from scratch. Additionally, AVN-944 acts against the synthesis of RNA in arenaviruses, effectively preventing arenavirus infections. Demonstrating a wide spectrum of anti-cancer properties, AVN-944 is utilized in research related to multiple myeloma (MM) and acute myeloid leukemia (AML).

    Product Information
    Catalog Num A13652
    Formula C25H27N5O5
    Molecular Weight 477.51
    CAS Number 297730-17-7
    SMILES CC[C@H](CC#N)OC(=O)N[C@@H](C)C1=CC(=CC=C1)NC(=O)NC2=CC(=C(C=C2)C3=CN=CO3)OC
    Synonyms AVN 944, AVN944, VX-944, VX 944, VX944
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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    This equation is commonly abbreviated as: C1V1 = C2V2

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