Nucleoside Antimetabolite/Analog

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  1. Adenosine Analog

    2'-O-t-Butyldimethylsilyladenosine is an adenosine analog that primarily targets adenosine receptors. This compound functions as a smooth muscle vasodilator and has demonstrated potential in inhibiting cancer progression. It is valuable for research applications in vascular biology and oncology, contributing to studies on therapeutic pathways involving adenosine signaling.
  2. Purine Nucleoside Analog

    8-Bromo-3'-deoxy-3'-fluoroguanosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanism of action primarily involves the inhibition of DNA synthesis and the induction of apoptosis in cancer cells. This compound is valuable for research related to cancer biology and therapeutic development.
  3. Purine Nucleoside Analog

    2-Aminopurine-9-beta-D-(3’,5’-di-O-benzoyl-2’-deoxy-2’-fluoro)arabinoriboside is a purine nucleoside analog that selectively targets key pathways in cellular proliferation. This compound demonstrates significant antitumor activity, particularly against indolent lymphoid malignancies, by inhibiting DNA synthesis and inducing apoptosis. Its unique structure allows for enhanced interaction with nucleic acids, making it a valuable tool for cancer research and therapeutic development.
  4. Polymer

    9,10-Epoxy-18-hydroxyoctadecanoic acid is a fundamental component of cutin, a polymer that plays a crucial role in plant defense. By forming a protective barrier, this compound minimizes pathogen infiltration and enhances waterproofing of leaves and fruits. It is significant for research in plant biology, particularly in studies focusing on plant resilience and response mechanisms to environmental stressors.
  5. Adenosine Analog

    2-Benzylthioadenosine is an adenosine analog that primarily acts on adenosine receptors. It is known for its vasodilatory effects on smooth muscle and has been investigated for its potential to inhibit cancer progression. This compound is valuable in research applications related to cardiovascular health and oncology, contributing to the understanding of adenosine signaling pathways.
  6. Purine Nucleoside Analog

    2'-O-Acetyl-3',5'-bis-O-benzoyl-6-aza-xylo uridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer effects are primarily attributed to the inhibition of DNA synthesis and the induction of apoptosis. This compound serves as a valuable tool for researchers investigating the mechanisms of cancer treatment and the development of therapeutic strategies targeting DNA replication and cellular apoptosis pathways.
  7. Purine Nucleoside Analog

    2',3'-Di-O-acetyl-D-uridine is a purine nucleoside analog that serves as a potential antitumor agent. It exhibits significant biological activity by inhibiting DNA synthesis and inducing apoptosis, making it relevant for research into treatment strategies for indolent lymphoid malignancies. This compound is useful for studying the mechanisms of cancer cell proliferation and therapeutic resistance in various malignancies.
  8. Thymidine Analog

    5-Benzylamino carbonyl-3'-O-acetyl-2'-O-methyl-5'-O-DMTr-uridine is a thymidine analog that exhibits insertional activity in replicated DNA. This compound serves as a valuable tool for labeling cells and monitoring DNA synthesis. Its structural modifications enhance its utility in various molecular biology applications, including studies on nucleic acid dynamics and cellular proliferation.
  9. Nucleoside Metabolite

    2-Hydroxy-3-(4-hydroxyphenyl)propenoate, a nucleoside metabolite, is characterized by its ability to influence various biochemical pathways. This compound exhibits significant biological activity, particularly in metabolic processes associated with nucleoside derivatives. It serves as a valuable tool for research applications focused on metabolic regulation and the study of nucleoside metabolism.
  10. Purine Nucleoside Analog

    3'-N-Acetyl-3'-amino-3'-deoxy-2',5'-di-O-acetyluridine is a purine nucleoside analog known for its broad antitumor activity against indolent lymphoid malignancies. Its primary mechanisms involve the inhibition of DNA synthesis and the induction of apoptosis in cancer cells. This compound holds significant potential for research applications in cancer biology and therapeutic development.
  11. Nucleoside Metabolite

    17-Hydroxylinolenic acid is a nucleoside metabolite involved in cellular signaling pathways. It has been shown to exert anti-inflammatory effects and modulate lipid metabolism. This compound is particularly valuable in research applications focused on understanding metabolic disorders and the role of fatty acids in cellular functions.
  12. Nucleoside Metabolite

    19-Oxotestosterone is a nucleoside metabolite that plays a significant role in androgen metabolism. This compound is useful for studying hormone regulation, particularly in relation to testosterone synthesis and its biological effects. Research applications include investigations into steroidogenesis and the modulation of androgen receptor activity in various biological systems.
  13. Guanosine Analog

    N2-iso-Butyryl-2'-O-(2-methoxyethyl)guanosine is a guanosine analog with immunostimulatory properties. It is capable of inducing type I interferons in certain animal models, thereby exhibiting antiviral effects. The efficacy of this compound is linked to its activation of Toll-like receptor 7 (TLR7), making it a valuable tool for studying immune responses and potential therapeutic applications in viral infections.
  14. Adenosine Analog

    N6-Benzoyl-2',3'-isopropylidene adenosine is an adenosine analog targeting adenosine receptors. This compound exhibits significant smooth muscle vasodilatory activity and has demonstrated potential in inhibiting cancer progression. Its applications in research include studying vascular physiology and cancer biology, making it a valuable tool in the investigation of therapeutic strategies involving adenosine modulation.
  15. Cytidine Analog

    N4-Benzoyl-7’-O-(4,4’-dimethoxytrityloxy)morpholinocytosine is a cytidine analog that functions primarily as an inhibitor of DNA methyltransferases. This compound exhibits potential anti-metabolic and anti-tumor activities, making it valuable for research applications in the study of epigenetic regulation and cancer biology. Its unique structural modifications enhance its stability and bioavailability, facilitating the investigation of cellular processes and therapeutic interventions.
  16. Purine Nucleoside Analog

    Rev 2’-O-MOE-5MeU-5’-amidite is a purine nucleoside analog that target DNA synthesis pathways. This compound exhibits significant anticancer activity, particularly against indolent lymphoid malignancies, by inducing apoptosis and inhibiting cell proliferation. It is a valuable tool for research applications in cancer biology and therapeutic development.
  17. Purine Nucleoside Analog

    2’-O-Acetyl-5’-O-(p-toluoyl)-3’-deoxy-3’-fluoro-5-trifluoromethyluridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanism of action involves the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research and therapeutic development. This compound serves as an effective reagent in studies focused on targeting nucleoside metabolism and exploring anticancer strategies.
  18. Guanosine Analog

    5’(R)-C-Methylguanosine is a guanosine analog that serves as a potent immunostimulatory agent. It has been shown to induce type I interferons in various animal models, thereby exhibiting significant antiviral properties. Additionally, the biological activity of this compound is closely linked to the activation of Toll-like receptor 7 (TLR7), making it valuable in research applications focused on immune response and antiviral therapies.
  19. Purine Nucleoside Analog

    2-Amino-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-9H-purine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanism of action involves the inhibition of DNA synthesis and the induction of apoptosis in malignant cells. This compound is valuable for research applications focused on cancer biology and therapeutic strategies targeting nucleoside metabolism.
  20. Phospho Amino Acid

    Erythro-5-Phosphooxy-L-lysine is a phospho amino acid that serves as a key intermediate in various biochemical pathways. This compound is primarily involved in cellular signaling and can influence protein interactions and activities through phosphorylation. Its applications in research include studying phospholipid metabolism, protein phosphorylation events, and the role of phospho amino acids in cellular regulation and signaling mechanisms.
  21. Purine Nucleoside Analog

    1,N6-Etheno-9-(β-D-xylofuranosyl)adenosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanism involves the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool in cancer research. This compound can be utilized in studies focused on understanding and targeting tumor cell proliferation and survival pathways.
  22. Tricarboxylic Acid

    (2Z,4E)-5-Hydroxypenta-2,4-diene-1,2,5-tricarboxylic acid is a tricarboxylic acid that demonstrates potential as a biochemical modulator. This compound is of interest for its ability to participate in metabolic pathways, particularly in the regulation of cellular energy states. It has applications in biochemical research, particularly in studies concerning metabolic diseases and the functioning of the tricarboxylic acid cycle.
  23. Purine Toxin

    Py-MAA-Val-Cit-PAB-DX8951 is a purine toxin that functions as an intermediate in the synthesis of antibody-drug conjugates. This compound is instrumental in developing targeted therapies, enhancing the efficacy of anticancer treatments, and improving specificity towards malignant cells. Its utilization in chemical research facilitates advancements in bioconjugation techniques and drug delivery systems.
  24. Antieoplastic Agent

    Flurocitabine, a fluorinated analog of cytosine arabinoside, acts as an antineoplastic agent by undergoing partial hydrolysis in vivo to produce two active metabolites: arabinosyl-fluorocytosine (ara-FC) and arabinosyl-fluorouracil (ara-FU). This compound demonstrates significant antitumor activity and has shown promise in phase I clinical studies for acute leukemia and various solid tumors. Its unique mechanism of action makes Flurocitabine a valuable tool for cancer research and therapy development.
  25. Guanosine Analog

    3’-β-C-Ethynylguanosine is a guanosine analog that acts as an immunostimulatory agent by inducing type I interferons, thereby exhibiting antiviral properties. Its efficacy is linked to the activation of Toll-like receptor 7 (TLR7), which plays a critical role in immune response. Additionally, this compound features an alkyne functional group, making it suitable for click chemistry applications, specifically copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules, facilitating the study of biochemical interactions.
  26. Purine Nucleoside Analog

    3’,5’-Di-O-benzoyl-2’-deoxy-2’-fluoro-3-Deaza-arabinouridine is a purine nucleoside analog that exhibits significant antitumor activity against indolent lymphoid malignancies. Its mechanism of action involves the inhibition of DNA synthesis and the induction of apoptosis in cancer cells, making it valuable for research into novel anticancer therapies. This compound serves as a crucial tool for investigating cellular responses and therapeutic strategies in oncology.
  27. Purine Nucleoside Analog

    2-Amino-2'-deoxy-N6,N6-dimethyl-2'-adenosine is a purine nucleoside analog that exhibits potent antitumor properties, particularly against indolent lymphoid malignancies. Its mechanism of action involves the inhibition of DNA synthesis and the induction of apoptosis in cancer cells. This compound serves as a valuable tool for research applications focused on understanding cancer biology and therapeutic strategies in oncology.
  28. Purine Nucleoside Analog

    2'-O-Me-2-thio-U-3'-phos phoramidite is a purine nucleoside analog that plays a crucial role in molecular biology research. This compound exhibits significant antitumor activity, particularly against indolent lymphoid malignancies, by inhibiting DNA synthesis and inducing apoptosis. It is valuable for studies focused on cancer treatment and therapeutic development.
  29. Purine Nucleoside Analog

    3’-Deoxy-3’-fluoroinosine is a purine nucleoside analogue that interferes with DNA synthesis and induces apoptosis, demonstrating significant antitumor activity. This compound is primarily used in research related to indolent lymphoid malignancies, offering insights into therapeutic strategies targeting cancerous tissues. Its unique mechanism of action makes it a valuable tool for studying purine metabolism and apoptotic pathways in cancer biology.
  30. Adenosine Analog

    N6-Methyladenosine N1-oxide is an adenosine analogue primarily known for its role as a smooth muscle vasodilator. This compound exhibits significant biological activity, including the potential to inhibit cancer progression, making it valuable in cancer research and cardiovascular studies. Its unique properties allow for exploration in various therapeutic applications within the realms of oncology and vascular biology.
  31. Nucleoside Analogue

    1-(2-C-β-Methyl-β-D-ribofuranosyl)-5-nitropyridine-2(1H)-one is a nucleoside analogue featuring a nitropyridine core structure. This compound exhibits potential antiviral activity and is valuable in research exploring nucleoside metabolism and the development of antiviral therapies. Its unique structural modifications may serve as a tool for studying nucleotide synthesis and its implications in cellular processes.
  32. Purine Nucleoside Analog

    1-β-D-Ribofuranosyl-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine is a purine nucleoside analog that exhibits significant antitumor properties. It primarily exerts its biological activity through the inhibition of DNA synthesis and the induction of apoptosis, making it valuable in the study of indolent lymphoid malignancies. This compound is useful for research applications focused on cancer therapeutics and the mechanisms of cancer cell proliferation.
  33. Purine Nucleoside Analog

    9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-methyl-9H-purine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. This compound functions primarily by inhibiting DNA synthesis and inducing apoptosis in cancer cells. It serves as a valuable tool in cancer research for exploring mechanisms of action and developing new therapeutic strategies.
  34. Purine Nucleoside Analog

    2',3'-Di-O-acetyl-8-benzyloxy-3'-deoxy-3'-fluoroguanosine is a purine nucleoside analog primarily known for its antitumor properties. This compound exhibits significant biological activity by inhibiting DNA synthesis and inducing apoptosis in cancer cells, making it a valuable tool in cancer research. It is particularly relevant for studies targeting indolent lymphoid malignancies, where purine nucleoside analogs can offer therapeutic potential.
  35. Purine Nucleoside Analog

    2′-Deoxy-2′-fluoro-3-deaza-arabinouridine is a purine nucleoside analog that exerts significant antitumor effects by inhibiting DNA synthesis and inducing apoptosis. This compound is particularly beneficial for research involving indolent lymphoid malignancies, providing insights into potential therapeutic strategies for cancer treatment. Its unique structure enhances its biological activity, making it a valuable tool in anticancer research applications.
  36. Purine Nucleoside Analog

    N3-Methyl-5-methyluridine is a purine nucleoside analog recognized for its potent antitumor activity against indolent lymphoid malignancies. This compound functions primarily by inhibiting DNA synthesis and inducing apoptosis, thereby regulating cell proliferation and promoting cancer cell death. Research applications include exploring mechanisms of cancer treatment and evaluating therapeutic strategies in hematological malignancies.
  37. Purine Nucleoside Analog

    5-Bromo-2'-deoxy-2'-fluoro-β-D-arabinouridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action involve the inhibition of DNA synthesis and induction of apoptosis, making it a valuable tool for cancer research. This compound is suitable for studies focused on understanding the molecular pathways of cancer and evaluating therapeutic interventions.
  38. Purine Nucleoside Analog

    2'-Deoxy-2'-fluoro-6-S-methyl-6-thio-arabino-inosine is a purine nucleoside analog that exhibits significant antitumor activity against indolent lymphoid malignancies. Its mechanism of action primarily involves the inhibition of DNA synthesis and the induction of apoptosis. This compound is valuable for research focused on cancer therapeutics and understanding the molecular pathways involved in tumor growth.
  39. Purine Nucleoside Analog

    3’-Azido-3’-deoxycytidine is a purine nucleoside analog that exhibits notable antitumor activity, primarily targeting indolent lymphoid malignancies. Its mechanism of action involves the inhibition of DNA synthesis and the induction of apoptosis. Additionally, this compound serves as a versatile click chemistry reagent, featuring an azide group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. It is also capable of undergoing strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN functionalized compounds, making it valuable in diverse chemical biology applications.
  40. Purine Nucleoside Analog

    5-O-TBDPS-1,2-di-O-isopropylidene-3-keto-alpha-D-xylofuranoside is a purine nucleoside analog that serves as an effective tool in the study of cancer biology. This compound exhibits significant antitumor activity, particularly against indolent lymphoid malignancies, through mechanisms such as the inhibition of DNA synthesis and induction of apoptosis. Its applications in research extend to the development of novel therapeutic strategies targeting specific malignancies.
  41. Purine Nucleoside Analog

    N,N-Dimethyl-2′-O-methyladenosine is a purine nucleoside analogue that exhibits significant antitumor activity. Its primary mechanisms include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool in research focused on indolent lymphoid malignancies. This compound is utilized in studies aimed at understanding cancer biology and exploring therapeutic strategies for lymphoproliferative disorders.
  42. Nucleoside Metabolite

    4-Oxo-4,5-dihydroimidazole-5-acetic acid is a nucleoside metabolite that plays a crucial role in nucleic acid metabolism. This compound influences the degradation and synthesis of nucleotides, making it valuable for studies focused on cellular proliferation and genetic regulation. Its applications extend to research in enzymatic activity involving nucleoside triphosphate pools and their effects on cellular processes.
  43. Thymidine Analog

    2',3',5'-Tri-O-benzoyl-5-hydroxy methyluridine is a thymidine analog known for its ability to integrate into replicated DNA. This compound exhibits insertional activity, making it useful for cell labeling and monitoring DNA synthesis in various experimental settings. Its application is valuable in studies focused on nucleic acid metabolism and cellular proliferation.
  44. Purine Nucleoside Analog

    9-(2'-O-Acetyl-5'-O-benzoyl-3'-deoxy-beta-D-ribofuranosyl)-6-chloropurine is a purine nucleoside analog that exerts broad antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research and therapeutic studies. This compound may also be useful in exploring the biochemical pathways associated with nucleoside metabolism and cancer cell proliferation.
  45. Purine Nucleoside Analog

    5’-Deoxy-5’-N,N-dimethylamino thymidine is a purine nucleoside analog that primarily targets DNA synthesis. It exhibits significant antitumor activity, particularly against indolent lymphoid malignancies, by inducing apoptosis and inhibiting cellular proliferation. This compound serves as a valuable tool for research in cancer biology and therapeutic development.
  46. Purine Nucleoside Analog

    3’-Azido-3’-deoxy-N6,N6-dimethyladenosine is a purine nucleoside analogue that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis. As a click chemistry reagent, it features an azide group, enabling copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) with reactive partners like DBCO or BCN. This versatility makes it a valuable tool for various research applications in chemical biology and medicinal chemistry.
  47. Purine Nucleoside Analog

    6-Chloro-2-hydroxy-9-(2',3',5'-tri-O-acetyl-β-D-ribofuranosyl)purine is a purine nucleoside analog that primarily targets nucleic acid synthesis. Its biological activity includes broad antitumor properties, particularly effective against indolent lymphoid malignancies. Mechanistically, it functions through the inhibition of DNA synthesis and the induction of apoptotic pathways, making it a valuable tool for cancer research and therapeutic development.
  48. Purine Nucleoside Analog

    N1-Methoxymethyl pseudouridine is a purine nucleoside analog that exhibits broad antitumor activity, particularly against indolent lymphoid malignancies. This compound functions by inhibiting DNA synthesis and inducing apoptosis, contributing to its effectiveness in cancer research. N1-Methoxymethyl pseudouridine serves as a valuable tool for investigating mechanisms of cancer cell proliferation and therapeutic responses.
  49. Nucleoside Metabolite

    CMP-2-Aminoethylphosphonate is a nucleoside metabolite that serves as a phosphonate analog of nucleotide structures. It is involved in various biochemical pathways and can be utilized in research applications focusing on nucleotide metabolism and cellular signaling. This compound may also provide insights into the role of nucleoside metabolites in cellular processes and their potential therapeutic applications.
  50. Purine Nucleoside Analog

    2-Chloro-2′-deoxy-N,N-dimethyladenosine is a purine nucleoside analog that primarily targets purine metabolism. This compound exhibits substantial antitumor activity, particularly against indolent lymphoid malignancies, by mechanisms including inhibition of DNA synthesis and induction of apoptosis. It serves as an important tool for research in cancer biology and therapeutic development.

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