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3’-Azido-3’-deoxycytidine

Purine Nucleoside Analog

3’-Azido-3’-deoxycytidine is a purine nucleoside analog that exhibits notable antitumor activity, primarily targeting indolent lymphoid malignancies. Its mechanism of action involves the inhibition of DNA synthesis and the induction of apoptosis. Additionally, this compound serves as a versatile click chemistry reagent, featuring an azide group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. It is also capable of undergoing strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN functionalized compounds, making it valuable in diverse chemical biology applications.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	70580-87-9
Applications	Purine Nucleoside Analog
Formula	C₉H₁₂N₆O₄
Molecular Weight	268.23
SMILES	OC[C@@H]1[C@@H](N=[N+]=[N-])[C@@H](O)[C@H](N2C(N=C(C=C2)N)=O)O1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.