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3’-β-C-Ethynylguanosine

Guanosine Analog

3’-β-C-Ethynylguanosine is a guanosine analog that acts as an immunostimulatory agent by inducing type I interferons, thereby exhibiting antiviral properties. Its efficacy is linked to the activation of Toll-like receptor 7 (TLR7), which plays a critical role in immune response. Additionally, this compound features an alkyne functional group, making it suitable for click chemistry applications, specifically copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules, facilitating the study of biochemical interactions.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	180300-56-5
Applications	Guanosine Analog
Formula	C₁₂H₁₃N₅O₅
Molecular Weight	307.26
SMILES	OC[C@@H]1[C@](O)(C#C)[C@@H](O)[C@H](N2C=NC3=C2N=C(N)NC3=O)O1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.