3’-β-C-Ethynylguanosine

Catalog No.: A56253
Guanosine Analog
3’-β-C-Ethynylguanosine is a guanosine analog that acts as an immunostimulatory agent by inducing type I interferons, thereby exhibiting antiviral properties. Its efficacy is linked to the activation of Toll-like receptor 7 (TLR7), which plays a critical role in immune response. Additionally, this compound features an alkyne functional group, making it suitable for click chemistry applications, specifically copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules, facilitating the study of biochemical interactions.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description3’-β-C-Ethynylguanosine is a guanosine analog that acts as an immunostimulatory agent by inducing type I interferons, thereby exhibiting antiviral properties. Its efficacy is linked to the activation of Toll-like receptor 7 (TLR7), which plays a critical role in immune response. Additionally, this compound features an alkyne functional group, making it suitable for click chemistry applications, specifically copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules, facilitating the study of biochemical interactions.
Product Information
Catalog NumA56253
FormulaC12H13N5O5
Molecular Weight307.26
CAS Number180300-56-5
SMILESOC[C@@H]1[C@](O)(C#C)[C@@H](O)[C@H](N2C=NC3=C2N=C(N)NC3=O)O1
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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