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6-Chloro-2-hydroxy-9-(2',3',5'-tri-O-acetyl-β-D-ribofuranosyl)purine

Purine Nucleoside Analog

6-Chloro-2-hydroxy-9-(2',3',5'-tri-O-acetyl-β-D-ribofuranosyl)purine is a purine nucleoside analog that primarily targets nucleic acid synthesis. Its biological activity includes broad antitumor properties, particularly effective against indolent lymphoid malignancies. Mechanistically, it functions through the inhibition of DNA synthesis and the induction of apoptotic pathways, making it a valuable tool for cancer research and therapeutic development.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	161923-50-8
Applications	Purine Nucleoside Analog
Formula	C₁₆H₁₇ClN₄O₈
Molecular Weight	428.78
SMILES	ClC1=NC(O)=NC2=C1N=CN2[C@@H]3O[C@H](COC(C)=O)[C@@H](OC(C)=O)[C@H]3OC(C)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.