Nucleoside Antimetabolite/Analog

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  1. Nucleoside Analog

    3'-O-TBDMS-2'-dA(Bz) is a nucleoside analog that serves as a key monomer for nucleic acid synthesis. It is widely utilized in the development of oligonucleotides, enabling advancements in genetic research, medicinal chemistry, and the synthesis of novel therapeutics. This compound provides enhanced stability and versatility in reaction conditions, facilitating the exploration of various biochemical pathways.
  2. Nucleoside Analog

    2'-Azido-dCTP is a nucleoside analog that serves as a building block in nucleic acid synthesis. This compound is utilized in various research applications, including the development of modified oligonucleotides and studies in gene expression. Its unique structure allows for incorporation into DNA, facilitating the exploration of nucleic acid functionality and stability.
  3. Nucleoside Metabolite

    OPC-8:0 is a nucleoside metabolite that serves as a crucial component in nucleotide synthesis and metabolic pathways. Its primary biological activity involves the modulation of nucleoside signaling, making it essential for various biochemical studies. This compound is commonly utilized in research applications focusing on cellular metabolism, nucleic acid synthesis, and the investigation of metabolic diseases.
  4. Nucleoside Analog

    Cytidine-5'-triphosphate trisodium is a nucleoside analog that serves as a critical monomer for nucleic acid synthesis. Its primary mechanism involves acting as a substrate for RNA polymerases and kinases, facilitating the incorporation of cytidine into RNA strands. This compound is essential for various applications in molecular biology, including RNA synthesis, enzyme studies, and nucleotide metabolism research.
  5. Nucleoside Analog

    DMTr-2'-O-Me-rU-3'-(D)-DPSE-phosphoramidite is a nucleoside analog designed for use in oligonucleotide synthesis. This phosphoramidite provides a versatile building block for the incorporation of modified ribonucleotides into RNA sequences. Its unique structure enhances stability and functionality, making it suitable for various molecular biology applications, including RNA probing and therapeutic development.
  6. Nucleoside Analog

    5-Hme-CTP is a monomeric nucleoside analog that serves as a substrate for nucleic acid synthesis. This compound is utilized in research applications involving the design and analysis of nucleic acid sequences, enabling the study of various biological processes. Its incorporation into nucleic acids can facilitate investigations into gene expression, replication, and repair mechanisms.
  7. Nucleoside Analog

    DMTr-2'-O-propyl-rU-3'-CE-phosphoramidite is a nucleoside analog designed for use in nucleic acid synthesis. This phosphoramidite monomer facilitates the incorporation of modified uridine residues, enhancing the stability and functionality of oligonucleotides. It serves as a valuable tool in the fields of oligonucleotide chemistry and molecular biology research.
  8. Purine Nucleoside Analog

    2’-Deoxy-2’-iodouridine, also known as 2’-iodo-2’-deoxyuridine, is a purine nucleoside analog that serves as an important tool in cancer research. This compound exhibits broad antitumor activity, particularly against indolent lymphoid malignancies, through mechanisms such as inhibition of DNA synthesis and induction of apoptosis. It is valuable for studies aimed at elucidating the molecular pathways involved in cancer cell growth and survival.
  9. Nucleoside Analog

    4'-Fluorouridine triphosphate (4'-F-UTP) is a nucleoside analog that serves as a substrate for RNA synthesis. It incorporates into RNA molecules, allowing for the study of RNA behavior and function. This reagent is valuable in research applications such as exploring RNA modification, gene expression, and the mechanism of action of antiviral compounds.
  10. Nucleoside Analog

    3'-O-TBDMS-2'-dC(Bz) is a nucleoside analog that serves as a key monomeric substrate for nucleic acid synthesis. This compound is utilized in the construction of oligonucleotides, enabling studies in genetic engineering, molecular biology, and therapeutic development. Its unique structural features facilitate incorporation into DNA and RNA sequences, making it a valuable reagent for researchers in the field of nucleic acid chemistry.
  11. Nucleoside Analog

    2'-O-MOE-GMP is a nucleoside analog that serves as a key building block in the synthesis of oligonucleotides. Its unique structural modifications enhance stability and bioavailability of oligonucleotides, making it valuable for various applications in molecular biology, including antisense therapy and RNA interference studies. This compound is instrumental in advancing research in gene expression and regulation.
  12. Thymidine Analog

    5-Cyanouridine is a thymidine analog that exhibits insertional activity within replicated DNA. This compound serves as a valuable tool for labeling cells and tracking DNA synthesis, making it useful in various molecular biology applications. Its unique properties facilitate the study of nucleic acid dynamics and cellular processes.
  13. Nucleoside Analog

    Thiol-modifier C6 S-S CE phosphoramidite is a synthetic nucleoside analog designed for the modification of oligonucleotides. This reagent facilitates the introduction of thiol groups into nucleic acids, enabling the formation of disulfide bonds, which can stabilize oligonucleotide structures and enhance their biological properties. Its primary applications include the synthesis of labeled or modified oligonucleotides for use in molecular biology and genetic research.
  14. Nucleoside Analog

    3'-O-TBDMS-2'-F-dG(iBu) is a nucleoside analog designed for use in nucleic acid synthesis. This compound features a 3'-TBDMS protective group and a 2'-fluorine substitution, enhancing its stability and reactivity in various synthetic protocols. It is instrumental in advancing research in fields such as oligonucleotide chemistry and genetic engineering.
  15. Nucleoside Analog

    DMTr-2'-F-dA(Bz)-3'-(L)-DPSE-phosphoramidite is a nucleoside analog designed for incorporation into oligonucleotides during DNA synthesis. This compound serves as a phosphoramidite monomer, providing a stable building block for generating modified nucleic acids. Its unique structural features facilitate the development of oligonucleotide-based probes and therapeutics, making it valuable for applications in molecular biology and genetic research.
  16. Adenosine Derivative

    7-CH-5'-dAMP, an adenosine derivative, serves as a potential substrate and competitive inhibitor for enzymes interacting with 2-deoxyadenosine-5-monophosphate. This compound is valuable in studying enzyme kinetics and mechanisms, particularly in the context of nucleotide metabolism and phosphotransfer reactions. Its modulation of enzymatic activity makes it a useful tool for exploring biological pathways involving adenine nucleotides.
  17. Nucleoside Analog

    2′-OMe-GDP is a nucleoside analog that serves as a valuable precursor in the synthesis of modified oligonucleotides. This compound is designed to enhance the stability and binding affinity of nucleic acids, making it useful for various applications in molecular biology and genetic research. Its incorporation into oligonucleotides can facilitate studies involving gene expression, RNA interference, and antisense therapies.
  18. Nucleoside Analog

    N4-Bz-5-Me-DMT-2'-O-MOE-Cr is a nucleoside analog featuring a dimethoxytrityl (DMT) protection group. It is primarily utilized in the synthesis of nucleic acids, serving as a crucial building block for the development of RNA and DNA sequences. This compound provides enhanced stability and compatibility in various biochemical applications, facilitating efficient oligonucleotide synthesis for research in genomics, molecular biology, and therapeutic development.
  19. Building block of Nucleic Acid

    2'-Deoxycytidine hydrate, a fundamental building block of nucleic acids, plays a critical role in DNA synthesis and repair. This nucleoside is essential for various molecular biology applications, including DNA cloning, sequencing, and amplification. Its incorporation into oligonucleotides facilitates studies on gene expression, mutation analysis, and therapeutic development.
  20. Nucleoside Analog

    6-Palmitamidohexyl CE phosphoramidite is a nucleoside analog that serves as a monomeric precursor for the synthesis of nucleic acids. This reagent plays a critical role in the preparation of oligonucleotides, facilitating studies in gene expression, molecular diagnostics, and therapeutic applications. Its unique structural properties enable the incorporation of hydrophobic moieties into nucleic acid sequences, contributing to the development of novel nucleic acid-based technologies.
  21. Building block of Nucleic Acid

    2-Amino-2'-fluoro-2'-deoxyadenosine serves as a crucial building block for nucleic acid synthesis. Its structural modifications enhance stability and binding affinity in nucleic acid interactions, making it an essential tool for researchers studying genetic material. This compound is widely applied in the development of modified oligonucleotides and therapeutic agents in nucleic acid research.
  22. Nucleoside Analog

    Cy3-dUTP is a nucleoside analog that serves as a valuable building block for the synthesis of nucleic acids. This fluorescently tagged nucleotide enables the incorporation of Cy3 into DNA during polymerization, facilitating visualization and study of nucleic acid interactions. Its applications include use in fluorescence microscopy, in situ hybridization, and other molecular biology techniques requiring detection of nucleic acids.
  23. Nucleotide

    2',3'-Cyclic UMP is a naturally occurring cyclic nucleotide that plays a critical role in cellular signaling pathways. Its biological activity is primarily linked to the regulation of RNA metabolism and signal transduction processes. This compound is valuable for research applications focused on nucleotide signaling, RNA function, and the study of cellular responses to various stimuli.
  24. Nucleoside Analog

    2'-F-AMP is a nucleoside analog that serves as a building block for the synthesis of oligonucleotides. Its fluorinated modification enhances thermal stability and hybridization properties, making it valuable for various molecular biology applications. This compound is utilized in the development of DNA and RNA-based therapeutics, as well as in the study of nucleic acid interactions and enzymatic processes.
  25. Nucleoside Analog

    2'-F-UMP is a nucleoside analog that serves as a building block for the synthesis of modified oligonucleotides. Its incorporation into nucleic acid sequences can enhance stability and provide unique properties for various biochemical assays. This compound is valuable in the fields of genetic research, therapeutic development, and molecular biology applications.
  26. Nucleoside Analog

    (2'OMe-5'p-A)pG is a nucleoside analog that serves as a key component in the synthesis of modified nucleic acids. This compound features a 2'-O-methyl modification, enhancing its stability and cellular uptake. It is widely utilized in research applications involving RNA synthesis, oligonucleotide design, and developing therapeutic agents targeting nucleic acids.
  27. Nucleoside Analog

    2'-F-ADP is a nucleoside analog that acts as a building block for oligonucleotide synthesis. Its structural modification enhances the stability and binding affinity of oligonucleotides, making it a valuable tool in molecular biology and genetic engineering research. 2'-F-ADP is utilized for the development of therapeutic oligonucleotides and for studies involving RNA interactions.
  28. Nucleoside Analog

    Fluorescein-12-UTP is a nucleoside analog that serves as a fluorescent label for RNA synthesis. Its primary application lies in the incorporation into RNA transcripts during in vitro transcription, allowing for the visualization and tracking of RNA molecules. This reagent is widely used in studies involving RNA localization, expression analysis, and other molecular biology applications.
  29. Nucleoside Analog

    DMTr-2',2'-diFluoro-dA(Bz)-3'-CE-phosphoramidite is a nucleoside analog utilized as a key monomer in oligonucleotide synthesis. This compound exhibits unique properties due to the presence of di-fluorinated modifications, enhancing the stability and affinity of nucleic acids. It serves as an essential building block for the development of modified oligonucleotides in various research applications, including gene therapy and molecular diagnostics.
  30. Nucleoside Analog

    Reverse abasic phosphoramidite is a nucleoside analog designed for use in nucleic acid synthesis. This compound serves as a monomeric raw material, facilitating the incorporation of abasic sites into oligonucleotides. Its unique properties make it valuable for studying the biochemical effects of abasic sites in DNA and RNA, enabling research in fields such as molecular biology and genetics.
  31. Oligonucleotide

    m7GpppGpG is an oligonucleotide that functions as an M7GpppNpG trinucleotide cap analogue. It effectively prevents premature degradation by 5′-exonucleases, thus stabilizing RNA molecules. Additionally, m7GpppGpG plays a crucial role in recruiting proteins essential for pre-mRNA splicing, mRNA transport, and the initiation of protein biosynthesis, making it valuable for various molecular biology and RNA research applications.
  32. Nucleoside Analog

    DMTr-2'-O-Me-rG(iBu)-3'-(L)-DPSE-phosphoramidite is a nucleoside analog primarily used as a monomer for nucleic acid synthesis. This compound facilitates the incorporation of modified nucleotides into oligonucleotide sequences, allowing researchers to study the structural and functional properties of nucleic acids. Its unique modifications enhance stability and binding characteristics, making it valuable in various applications, including antisense research, gene therapy, and RNA interference studies.
  33. Nucleoside Analog

    2′-O-MOE-CMP is a nucleotide analog specifically designed for oligonucleotide synthesis. This compound functions by enhancing the stability and affinity of nucleic acid constructs, making it useful in various molecular biology applications. Its incorporation into oligonucleotides can improve resistance to nucleases and enhance binding properties, facilitating research in gene expression and antisense oligonucleotides.
  34. Nucleotide

    3′-GMP is a nucleotide involved in various biological processes, including RNA synthesis and signaling. It serves as a phosphoribosyl donor and plays a critical role in cellular metabolism. Research applications of 3′-GMP include studies on nucleotide metabolism, enzyme activity, and signal transduction pathways.
  35. Nucleoside Analog

    2'-O-Propargyl-rC(Ac) is a nucleoside analog that serves as a versatile monomer for nucleic acid synthesis. Its propargyl group facilitates various chemical modifications, enhancing the structural diversity of RNA molecules. This compound is valuable for applications in RNA research, including the development of RNA probes and therapeutic oligonucleotides.
  36. Nucleoside Analog

    DMTr-2'-O-Me-rA(Bz)-3'-(L)-DPSE-phosphoramidite is a nucleoside analog designed for use in nucleic acid synthesis. This phosphoramidite serves as a monomeric building block, enabling the incorporation of modified nucleotides into oligonucleotides. Its application extends to various research areas, including gene delivery and RNA therapeutics development.
  37. Nucleoside Analog

    DMTr-2'-O-propyl-rG(iBu)-3'-CE-phosphoramidite is a nucleoside analog specifically designed for oligonucleotide synthesis. This phosphoramidite derivative enables the incorporation of modified guanine residues into nucleic acid sequences, enhancing their properties for various research applications. It is particularly valuable for studies involving antisense oligonucleotides, RNA interference, and the development of nucleic acid-based therapeutics.
  38. Nucleoside Analog

    N2-Isobutyryl-2'-O,4'-C-methyleneguanosine is a nucleoside analog designed for use in nucleic acid synthesis. This compound features a unique modified structure that enhances its stability and incorporation into RNA sequences, making it an essential reagent for studies in molecular biology and genetic engineering. Its applications extend to investigating RNA function, structure, and the development of novel therapeutics.
  39. Nucleoside Analog

    DMTr-2'-F-dG(iBu)-3'-(L)-DPSE-phosphoramidite is a nucleoside analog that serves as a key building block for nucleic acid synthesis. This compound is designed to facilitate the incorporation of modified nucleotides into oligonucleotide sequences, enhancing stability and specificity. Its applications include the development of antisense oligonucleotides, siRNA, and other nucleic acid-based therapeutics, making it valuable for research in gene regulation and molecular biology.
  40. Nucleoside Analog

    5'-O-DMTr-2'-O-Me-rA is a nucleoside analog that serves as a versatile building block for nucleic acid synthesis. Its unique chemical modifications enhance stability and efficacy in various biochemical applications. This compound is instrumental in the development of modified oligonucleotides, enabling advancements in RNA therapeutics and molecular biology research.
  41. Nucleoside Analog

    N-Butyl molnupiravir is a nucleoside analog that serves as a crucial building block for nucleic acid synthesis. This compound exhibits antiviral properties and has potential applications in virology research, particularly in the development of therapeutics against RNA viruses. Its modification allows for enhanced stability and effectiveness in various experimental settings.
  42. Nucleoside Analog

    SPS ATP is a nucleoside analog that serves as a critical monomeric substrate in nucleic acid synthesis. Its incorporation into RNA and DNA strands enables the study of nucleic acid structure and function. This reagent is essential for applications in molecular biology, including the development of RNA therapies and the exploration of genetic mechanisms.
  43. Nucleoside Metabolite

    3α,7α-Dihydroxycoprostane is a nucleoside metabolite derived from cholest-4-en-3-one-7α-ol. This compound exhibits biological activity relevant to lipid metabolism and can be instrumental in studying the pathways involved in steroid biosynthesis. Its applications extend to research focused on endocrine function and metabolic diseases, providing essential insights into the biological roles of sterols in cellular processes.
  44. Nucleoside

    5'-O-Dmt-n2-isobutyryl-2'-o-methyl-d-guanosine is a modified nucleoside that features a 5' oxygen dimethyl group and a 2' methyl substitution. It exhibits significant affinity for tissues, demonstrated through chemotactic assays, making it a valuable tool for investigating nucleoside transport and cellular localization. This compound is useful in various research applications, including studies of nucleoside metabolism and signaling pathways.
  45. Purine Nucleoside Analog

    5-Ethyluridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly in the treatment of indolent lymphoid malignancies. Its anticancer mechanisms include the inhibition of DNA synthesis and the induction of apoptosis. This compound serves as a valuable tool for research applications focusing on cancer therapy and the understanding of cancer cell metabolism.
  46. Nucleoside

    2'-Deoxy-L-guanosine is a nucleoside that selectively inhibits the phosphorylation of D-Thymidine catalyzed by herpes simplex virus type 1 (HSV-1) thymidine kinase. This compound serves as a valuable tool in studying viral infection mechanisms and nucleoside metabolism. Its unique structure and inhibitory properties make it suitable for research applications in virology and nucleoside biochemistry.
  47. Nucleoside Analog

    iBu-dG (N2-Isobutyryl-2'-deoxyguanosine) is a nucleoside analog targeting DNA synthesis. It serves as a key building block for the production of oligoribonucleotides, facilitating research in molecular biology and genetic engineering. iBu-dG is valuable for studies involving nucleotide modification and nucleic acid structures.
  48. Nucleoside Analog

    DMTr-2'-O-C22-rU-3'-CE-phosphoramidite is a nucleoside analog designed for the efficient synthesis of oligonucleotides. This compound serves as a key building block in the construction of RNA sequences, enabling studies in gene expression, RNA interference, and other nucleic acid-based research applications. Its unique 2'-O modification enhances stability and binding properties, making it valuable for various experimental designs in molecular biology.
  49. Cap Reagent

    Im-m7GDP sodium is a cap reagent that facilitates the synthesis of modified nucleic acids. This compound is essential for the incorporation of a methyltetrahydro-2H-pyran-2-yl group into the 5' end of RNA, enhancing stability and translation efficiency. It is widely utilized in the production of mRNA for vaccine development and other therapeutic applications.
  50. Nucleoside Antimetabolite/Analog

    2'-O-(2-Methoxyethyl)-uridine is a nucleoside analog that acts as an antimetabolite, specifically targeting RNA synthesis. This synthetic compound exhibits significant potential in the development of chemotherapeutic agents, making it a valuable tool for research in cancer therapeutics and RNA-related studies. Its structural modifications enhance stability and bioavailability, offering insights into nucleoside pharmacology and mechanism of action.

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