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DMTr-2'-F-dG(iBu)-3'-(L)-DPSE-phosphoramidite

Nucleoside Analog

DMTr-2'-F-dG(iBu)-3'-(L)-DPSE-phosphoramidite is a nucleoside analog that serves as a key building block for nucleic acid synthesis. This compound is designed to facilitate the incorporation of modified nucleotides into oligonucleotide sequences, enhancing stability and specificity. Its applications include the development of antisense oligonucleotides, siRNA, and other nucleic acid-based therapeutics, making it valuable for research in gene regulation and molecular biology.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	2227139-97-9
Applications	Nucleoside Analog
Formula	C₅₄H₅₈FN₆O₈PSi
Molecular Weight	997.13
SMILES	COC(C=C1)=CC=C1C(C2=CC=C(C=C2)OC)(C3=CC=CC=C3)OC[C@@H]4[C@@H](O[P@@]5N6[C@](CCC6)([H])[C@H](O5)C[Si](C7=CC=CC=C7)(C8=CC=CC=C8)C)[C@@H](F)[C@H](N9C%10=C(C(N=C(N%10)NC(C(C)C)=O)=O)N=C9)O4

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.