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DMTr-2',2'-diFluoro-dA(Bz)-3'-CE-phosphoramidite

Nucleoside Analog

DMTr-2',2'-diFluoro-dA(Bz)-3'-CE-phosphoramidite is a nucleoside analog utilized as a key monomer in oligonucleotide synthesis. This compound exhibits unique properties due to the presence of di-fluorinated modifications, enhancing the stability and affinity of nucleic acids. It serves as an essential building block for the development of modified oligonucleotides in various research applications, including gene therapy and molecular diagnostics.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	3055573-22-0
Applications	Nucleoside Analog
Formula	C₄₇H₅₀F₂N₇O₇P
Molecular Weight	893.91
SMILES	COC(C=C1)=CC=C1C(C2=CC=CC=C2)(C3=CC=C(OC)C=C3)OC[C@@H]4[C@@H](OP(OCCC#N)N(C(C)C)C(C)C)C(F)(F)[C@H](N5C=NC6=C(NC(C7=CC=CC=C7)=O)N=CN=C65)O4

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.