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DMTr-2'-O-Me-rG(iBu)-3'-(L)-DPSE-phosphoramidite

Nucleoside Analog

DMTr-2'-O-Me-rG(iBu)-3'-(L)-DPSE-phosphoramidite is a nucleoside analog primarily used as a monomer for nucleic acid synthesis. This compound facilitates the incorporation of modified nucleotides into oligonucleotide sequences, allowing researchers to study the structural and functional properties of nucleic acids. Its unique modifications enhance stability and binding characteristics, making it valuable in various applications, including antisense research, gene therapy, and RNA interference studies.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	2227139-95-7
Applications	Nucleoside Analog
Formula	C₅₅H₆₁N₆O₉PSi
Molecular Weight	1009.17
SMILES	CO[C@@H]1[C@H](O[P@@]2N3[C@](CCC3)([H])[C@H](O2)C[Si](C4=CC=CC=C4)(C5=CC=CC=C5)C)[C@@H](COC(C(C=C6)=CC=C6OC)(C7=CC=C(OC)C=C7)C8=CC=CC=C8)O[C@H]1N9C=NC%10=C9NC(NC(C(C)C)=O)=NC%10=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.