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m7GpppGpG

Catalog No.: A56620
Oligonucleotide
m7GpppGpG is an oligonucleotide that functions as an M7GpppNpG trinucleotide cap analogue. It effectively prevents premature degradation by 5′-exonucleases, thus stabilizing RNA molecules. Additionally, m7GpppGpG plays a crucial role in recruiting proteins essential for pre-mRNA splicing, mRNA transport, and the initiation of protein biosynthesis, making it valuable for various molecular biology and RNA research applications.
m7GpppGpG 133608-76-1 Oligonucleotide
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Descriptionm7GpppGpG is an oligonucleotide that functions as an M7GpppNpG trinucleotide cap analogue. It effectively prevents premature degradation by 5′-exonucleases, thus stabilizing RNA molecules. Additionally, m7GpppGpG plays a crucial role in recruiting proteins essential for pre-mRNA splicing, mRNA transport, and the initiation of protein biosynthesis, making it valuable for various molecular biology and RNA research applications.
Product Information
Catalog NumA56620
FormulaC31H41N15O25P4
Molecular Weight1147.64
CAS Number133608-76-1
SMILESO=P(O)(OC[C@@H]1[C@@H](OP(O)(OC[C@H]2O[C@@H](N3C(NC(N)=NC4=O)=C4N=C3)[C@H](O)[C@@H]2O)=O)[C@@H](O)[C@H](N5C(NC(N)=NC6=O)=C6N=C5)O1)OP(OP(OC[C@H]7O[C@@H](N8C(NC(N)=N9)=C([N+](C)=C8)C9=O)[C@H](O)[C@@H]7O)([O-])=O)(O)=O
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DNA Damage > Nucleoside Antimetabolite/Analog