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m7GpppGpG

Oligonucleotide

m7GpppGpG is an oligonucleotide that functions as an M7GpppNpG trinucleotide cap analogue. It effectively prevents premature degradation by 5′-exonucleases, thus stabilizing RNA molecules. Additionally, m7GpppGpG plays a crucial role in recruiting proteins essential for pre-mRNA splicing, mRNA transport, and the initiation of protein biosynthesis, making it valuable for various molecular biology and RNA research applications.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	133608-76-1
Applications	Oligonucleotide
Formula	C₃₁H₄₁N₁₅O₂₅P₄
Molecular Weight	1147.64
SMILES	O=P(O)(OC[C@@H]1[C@@H](OP(O)(OC[C@H]2O[C@@H](N3C(NC(N)=NC4=O)=C4N=C3)[C@H](O)[C@@H]2O)=O)[C@@H](O)[C@H](N5C(NC(N)=NC6=O)=C6N=C5)O1)OP(OP(OC[C@H]7O[C@@H](N8C(NC(N)=N9)=C([N+](C)=C8)C9=O)[C@H](O)[C@@H]7O)([O-])=O)(O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.