Catalog No.
Product Name
Application
Product Information
Citations
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Phosphonamide Acid
2'-OMe-4'-ODMT-5'-NO2 phenoxybutyric acid is a phosphonamide acid primarily utilized in nucleic acid synthesis. This compound serves as a key intermediate for the development of modified oligonucleotides, enhancing stability and binding affinity. It is valuable for applications in molecular biology, drug development, and genetic research. -
Nucleoside Analog
CTPαS (Sp isomer) is a nucleoside analog that serves as a crucial monomeric substrate for nucleic acid synthesis. This compound is particularly valuable in the study of molecular biology and genetic research, facilitating the development of oligonucleotides and other nucleic acid-based technologies. Researchers can utilize CTPαS (Sp isomer) to explore nucleotide incorporation mechanisms and investigate various biochemical pathways. -
Nucleoside Analog
2′-F-UDP is a nucleoside analog that serves as a building block in the synthesis of oligonucleotides. Its structural modifications provide enhanced stability and affinity for target sequences, making it valuable in various research applications, including genetic studies, RNA structure analysis, and the development of diagnostic tools. 2′-F-UDP is particularly useful in studies aimed at understanding nucleotide interactions and enhancing the efficacy of nucleic acid-based therapeutics. -
Nucleoside Analog
DMTr-S-5-C-Me-2'-O-Me-rC(Ac)-3'-CE-phosphoramidite is a nucleoside analog utilized in the synthesis of oligonucleotides. This phosphoramidite derivative features several modifications, enhancing stability and facilitating incorporation into nucleic acid sequences. It is suitable for applications in DNA and RNA synthesis, aiding in the development of therapeutics and diagnostics. -
Purine Nucleoside Analog
(2R,3S,4R)-2-(Hydroxymethyl)tetrahydrothiophene-3,4-diol is characterized as a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanism of action involves the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable compound for cancer research. This reagent is useful in studies focused on understanding the cellular effects of purine metabolism and the development of targeted cancer therapies. -
Nucleoside Analog
3′-O-Azidomethyl-UTP is a nucleoside analog that serves as a versatile monomer for nucleic acid synthesis. Its unique azido group allows for specific modifications and incorporation into RNA strands, facilitating the study of RNA biology and the development of RNA-based therapeutics. This reagent is ideal for applications in molecular biology, including in vitro transcription and the creation of modified nucleic acid constructs. -
Nucleoside Analog
DMTr-2'-O-C6-rA(Bz)-3'-CE-Phosphoramidite is a nucleoside analog designed for use in solid-phase synthesis of oligonucleotides. It serves as a phosphoramidite monomer, allowing for the incorporation of modified nucleotide units into RNA and DNA sequences. This compound is essential for advancing research in areas such as gene expression studies, antisense oligonucleotide design, and therapeutic applications involving nucleic acids. -
Nucleoside Analog
5'-DMTr-LNA-N6-Bz-A is a nucleoside analog designed for incorporation into nucleic acid sequences. This monomer exhibits enhanced stability and binding affinity, making it suitable for applications in oligonucleotide synthesis and development of therapeutics. Its modified structure offers potential advantages in gene regulation and antisense therapy research. -
Nucleoside Analog
3-Deoxy-1,2-O-isopropylidene-α-D-ribofuranose is a nucleoside analog that serves as a valuable building block for nucleic acid synthesis. Its structure enables the incorporation of modified sugar units into oligonucleotides, facilitating studies in molecular biology and biochemistry. This compound is essential for exploring the role of nucleoside modifications in nucleic acid stability, hybridization properties, and therapeutic applications. -
Nucleotide
Cytidine, 5′-(P,P′,P′′,P′′-tetrahydrogen imidotriphosphate) is a non-hydrolyzable nucleotide that serves as a stable analog of ATP. Its primary mechanism involves the inhibition of nucleotide hydrolysis, making it suitable for studying nucleotide interactions and enzymatic activities. This reagent is valuable for research applications such as exploring nucleotide metabolism, signaling pathways, and investigating the roles of nucleotides in cellular processes. -
Nucleoside Analog
DMTr-R-5'-C-Me-2'-O-Me-rA(Bz)-3'-CE-phosphoramidite is a nucleoside analog that serves as a building block for nucleic acid synthesis. This compound enhances the stability and flexibility of oligonucleotides, making it valuable for various applications in molecular biology, including the development of antisense oligonucleotides and siRNA. Its unique modifications allow for improved cellular uptake and therapeutic efficacy in gene modulation studies. -
Nucleoside Analog
GTPαS is a stable analog of guanosine triphosphate (GTP) that acts as a substrate for nucleic acid synthesis. It is predominantly utilized in cellular signaling studies and can inhibit GTPase activities, serving as a valuable tool in examining the functions of GTP-binding proteins. Its applications extend to investigations in molecular biology, particularly in the study of gene expression and regulatory mechanisms. -
Thymidine Phosphorylase Inhibitor
5-Phenyluracil is a potent inhibitor of thymidine phosphorylase, an enzyme involved in nucleoside metabolism. This compound exhibits significant anti-tumor activity by disrupting the salvage pathway of nucleotides, making it relevant for cancer research. Its selective inhibition of thymidine phosphorylase highlights its potential utility in exploring cancer therapeutics and related biological pathways. -
Nucleoside Analog
dTTPαS is a nucleoside analog that serves as a substrate for DNA polymerases during nucleic acid synthesis. It is utilized in research applications involving DNA replication and transcription studies. Its incorporation into DNA can aid in the design of experiments focusing on nucleotide incorporation fidelity and the exploration of DNA repair mechanisms. -
Nucleoside Analog
DMTr-2'-O-Propargyl-rU-3'-CE-phosphoramidite is a nucleoside analog designed for incorporation into RNA sequences during nucleic acid synthesis. This phosphoramidite derivative enables the introduction of propargyl groups, facilitating subsequent click chemistry applications and modifications. It is suitable for research in fields such as oligonucleotide development, RNA engineering, and therapeutic applications. -
Nucleoside Analog
DMTr-2'-O-C6-rC(Bz)-3'-CE-phosphoramidite is a nucleoside analog designed for the synthesis of oligonucleotides. This monomer is specifically utilized in automated DNA and RNA synthesis, contributing to the development of modified nucleic acids with enhanced stability and functionality. Applications include the production of therapeutically relevant RNA molecules and other nucleic acid constructs for research purposes. -
Antitumor Agent
DL-Alanosine is an amino acid analogue that acts primarily as an antitumor agent. It exhibits potent antitumor activities, making it a valuable reagent for cancer research. This compound can be utilized in studies focused on tumor cell metabolism and therapeutic resistance mechanisms. -
Nucleotide Derivative
DMT-dT is a nucleotide derivative that functions as a high-performance building block for DNA synthesis. It is commonly utilized in oligonucleotide synthesis and other molecular biology applications that require precision in nucleotide incorporation. With its unique chemical modifications, DMT-dT enhances the efficiency and fidelity of DNA strand assembly. -
Nucleoside Analog
DNA 5-Ethynyl(TIPS)-U amidite is a nucleoside analog used as a monomeric building block in oligonucleotide synthesis. Its ethynyl group enables bioconjugation applications and facilitates the study of nucleic acid interactions. This reagent is essential for researchers focusing on advanced nucleic acid chemistry and the development of novel therapeutic agents. -
Nucleoside Analog
DMTr-2'-O-Me-rU-3'-(L)-PSM-phosphoramidite is a nucleoside analog primarily utilized in nucleic acid synthesis. This unique monomeric reagent enables the incorporation of modified nucleotides, facilitating the generation of RNA and DNA sequences with enhanced stability and functionality. Its specific structure allows for optimized binding and recognition in various molecular biology applications, including gene expression studies and oligonucleotide design. -
Nucleoside Analog
5'-O-DMTr-2'-O-TOM-rA(Ac) is a nucleoside analog utilized in nucleic acid synthesis. This compound serves as a versatile building block for the assembly of oligonucleotides, facilitating the research of RNA structure and function. Its protective groups are designed for efficient incorporation during solid-phase synthesis, enabling the creation of modified nucleotides for various molecular biology applications. -
Nucleoside Analog
DMTr-2'-F-dU-3'-(D)-DPSE-phosphoramidite is a nucleoside analog designed for incorporation into oligonucleotides during automated solid-phase synthesis. It serves as a valuable building block for the creation of modified nucleic acids, enabling researchers to study nucleic acid function and stability. This reagent is particularly useful in applications such as genomics and antisense oligonucleotide development. -
dG Nucleoside
Dmf-dg (2'-Deoxy-N2-dimethylaminomethylene-guanosine) is a modified deoxyguanosine (dG) nucleoside featuring dimethylaminomethylamidine (DMF) protection. This compound serves as a critical building block in oligonucleotide synthesis, allowing for the incorporation of modified nucleotides into nucleic acid sequences. Its unique structural properties facilitate research applications in genetic engineering, molecular biology, and therapeutic development. -
Nucleoside Analog
Spacer Phosphoramidite 9 is a nucleoside analog that serves as a crucial monomeric building block for nucleic acid synthesis. Its structure facilitates the incorporation of spacer arms into oligonucleotides, allowing for precise control over spatial arrangements in nucleic acid assemblies. This reagent is valuable in various research applications, including DNA/RNA synthesis, molecular biology studies, and the development of therapeutic oligonucleotides. -
Nucleoside Analog
3'-O-TBDMS-2'-F-dA(Bz) is a nucleoside analog with a primary mechanism of incorporation into nucleic acid sequences. This compound serves as a crucial building block for the synthesis of modified nucleotides, enabling researchers to investigate nucleic acid function and stability. Its fluorinated structure enhances the stability and binding affinity of nucleic acid constructs, making it useful in various applications, including antisense oligonucleotide design and gene expression studies. -
Nucleoside Analog
DMTr-2'-F-dA(Bz)-3'-(D)-DPSE-phosphoramidite is a nucleoside analog that serves as a versatile monomer for nucleic acid synthesis. This compound plays a crucial role in the incorporation of modified nucleotides into oligonucleotides, enhancing stability and offering unique biochemical properties. Its applications include the development of RNA and DNA probes, as well as in the synthesis of oligonucleotides with tailored functionalities for various research purposes. -
Building block of Nucleic Acid
7-Methylguanosine 5′-monophosphate is a key building block of nucleic acids, functioning primarily as a nucleotide necessary for RNA synthesis. This compound plays a crucial role in the preservation of RNA stability and regulation of gene expression. It is widely used in molecular biology studies and applications involving RNA-based research, including the synthesis of modified RNA molecules and the investigation of RNA-protein interactions. -
Nucleoside Analog
(2'OMe-5'p-m6A)pG is a nucleoside analog primarily utilized in nucleic acid synthesis. This monomeric raw material enhances the stability and functionality of oligonucleotides, making it valuable for various research applications, including the development of antisense oligonucleotides and RNA interference studies. Its unique structure allows for improved binding properties and biological activity in molecular biology research. -
Active Compound
5'-O-DMT-ibu-rG is a DNA-binding compound designed to serve as a model for innovative therapeutic agents. It demonstrates promising activity in identifying potent and selective anti-cancer properties. This reagent can be utilized in research applications aimed at developing and screening new anti-cancer drugs. -
Purine Nucleoside Analog
DMTr-LNA-C(Bz)-3-CED-phosphoramidite is a purine nucleoside analog designed for the synthesis of oligonucleotides. This compound is essential for incorporating locked nucleic acid (LNA) modifications into oligonucleotide sequences, enhancing thermal stability and binding affinity. It is applicable in various research areas, including gene regulation studies, antisense therapy, and the development of molecular probes. -
Nucleoside Analog
DMTr-2'-O-Me-rU-3'-(L)-DPSE-phosphoramidite is a nucleoside analog designed for use in nucleic acid synthesis. This phosphoramidite serves as a monomeric building block, enabling the incorporation of modified nucleotides into oligonucleotides. Its utilization can enhance the stability and binding properties of nucleic acid constructs, making it valuable for applications in molecular biology and genetic research. -
Nucleoside Analog
DMTr-2'-O-C6-rG(iBu)-3'-CE-phosphoramidite is a nucleoside analog primarily utilized in the synthesis of oligonucleotides. This phosphoramidite derivative features a 2'-O-modification, enhancing compatibility with various biological applications. It serves as a key building block in the development of antisense oligonucleotides, RNA interference studies, and other nucleic acid-based research initiatives. -
Adenosine derivative
2-Methylthio-cis-zeatin riboside (ms2io6A) is a hypermodified adenosine derivative known for its presence in the transfer RNA of Salmonella typhimurium. This compound plays a critical role in the stabilization and modification of tRNA molecules, influencing protein synthesis and cellular function. Researchers utilize 2-Methylthio-cis-zeatin riboside in studies focusing on tRNA modification, gene expression regulation, and the biochemical pathways of bacterial translation. -
Nucleoside Analog
2'-O-Propargylcytidine is a nucleoside analog that serves as a key building block for nucleic acid synthesis. Its unique propargyl group allows for specific modifications in RNA and DNA, facilitating research in gene editing, oligonucleotide development, and synthetic biology. This compound is essential for studies focusing on RNA structure and function, as well as for the design of novel therapeutic agents. -
Purine Nucleoside Analog
8-Methylguanosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis. This compound is commonly utilized in research applications focused on cancer therapeutics and the study of nucleoside metabolism. -
Thymidine Analog
1-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)thymine 3'-CE phosphoramidite is a thymidine analog that acts as an effective substrate for DNA polymerases. This compound exhibits incorporation activity into replicated DNA, making it a valuable tool for labeling and tracking DNA synthesis in various biological studies. Its unique structural modifications enable researchers to explore nucleotide dynamics and cellular activities related to DNA replication. -
Nucleoside Analog
3'-NH2-ddC is a nucleoside analog that serves as a vital precursor in nucleic acid synthesis. Its primary mechanism involves acting as a substrate for DNA polymerases, facilitating the incorporation of this modified nucleotide into DNA strands. This compound is essential for research applications in molecular biology, particularly in the development of antiviral therapies and in the study of nucleic acid structures. -
Nucleoside Transport Inhibitor
Nitrobenzylthioinosine 5'-monophosphate (NBMPR-P) is a prodrug of the effective nucleoside transport inhibitor Nitrobenzylthioinosine (NBMPR). This compound primarily functions by blocking nucleoside transport in vivo, thereby mitigating host toxicity during high-dose Tubercidin treatment in tumor-bearing mice. NBMPR-P is valuable in research applications focusing on nucleoside transport mechanisms and related therapeutic interventions. -
Nucleoside Analog
5-Aminpropargyl UTP is a nucleoside analog that serves as a versatile monomer for nucleic acid synthesis. This compound enhances RNA labeling and offers a unique terminal modification, making it suitable for bioconjugation and biochemical studies. Its incorporation into oligoribonucleotides can facilitate research applications in gene expression, molecular biology, and RNA-based therapeutics. -
Enzymes Inhibitor
5'-dUMPS is a competitive inhibitor of enzymes interacting with 2'-deoxypyrimidine-5'-monophosphate. It plays a crucial role in modulating nucleic acid synthesis and can be utilized in research focused on metabolic pathways and enzyme kinetics. Its capacity to regulate enzyme activity makes it a valuable tool for studies in molecular biology and pharmacology. -
Nucleoside Analog
2'-O-4'-C-Locked-rC(Bz) is a nucleoside analog featuring a modified ribonucleotide structure. It serves as a valuable monomeric raw material for nucleic acid synthesis, enabling the development of oligonucleotides with enhanced stability and biological activity. This compound is particularly useful in studies involving RNA structure-function relationships and the design of RNA-based therapeutics. -
Nucleoside Analog
pApG is a nucleoside analog that serves as a monomeric building block for nucleic acid synthesis. It is utilized in biochemical research for the development of oligonucleotides and the study of nucleic acid interactions. Additionally, pApG may assist in the investigation of enzyme activities and the modulation of RNA and DNA functionality in various biological systems. -
Purine Nucleoside Analog
3’,5’-Bis-O-benzoyl-2’-deoxy-2’-fluoro-β-D-arabinouridine is a purine nucleoside analog that exhibits significant antitumor activity, specifically targeting indolent lymphoid malignancies. Its mechanism of action involves the inhibition of DNA synthesis and the induction of apoptosis in cancer cells. This compound is useful in cancer research, particularly for studies investigating therapeutic strategies against lymphoid cancers. -
Nucleoside Analog
5-Formyl-CTP is a nucleoside analog that serves as a crucial monomeric building block for nucleic acid synthesis. It plays a key role in various molecular biology applications, including the construction of DNA and RNA sequences. This compound is valuable in research settings focused on gene expression, genetic engineering, and the development of synthetic biology tools. -
Nucleoside Analog
3'-P-dTTP is a nucleoside analog that serves as a vital component for nucleic acid synthesis. Its incorporation into DNA strands facilitates the study of replication processes and the development of synthetic nucleic acids. 3'-P-dTTP is essential for exploring enzyme kinetics and for applications in gene editing and molecular biology research. -
Nucleoside Analog
2′-O-MOE-AMP is a nucleoside analog that serves as a building block for oligonucleotide synthesis. Its modification enhances the stability and efficiency of oligonucleotides, making it valuable in various molecular biology applications. This compound is particularly useful in the development of therapeutics and diagnostic tools, as well as in studies involving gene expression and regulation. -
Nucleoside Analog
Thymidine 5′-diphosphate disodium is a nucleoside analog that serves as an essential monomer for nucleic acid synthesis. It plays a critical role in DNA and RNA polymerization processes, facilitating the incorporation of thymidine into nucleic acid strands. This reagent is particularly valuable in molecular biology research, synthetic biology, and the development of nucleic acid-based therapeutics. -
Nucleoside Analog
5-Azdio-UTP is a nucleoside analog that serves as a monomeric building block for nucleic acid synthesis. Its unique structure allows for incorporation into RNA molecules, providing valuable insights into RNA biology and function. This reagent is useful in research applications such as studying RNA transcription and the development of RNA-based therapeutics. -
Nucleoside Analog
Peracetylated GalNAc PEG linker-azide is a versatile nucleoside analog designed for efficient nucleic acid synthesis. This compound features a peracetylated galactosamine moiety linked to a polyethylene glycol (PEG) azide, facilitating conjugation reactions. It is particularly valuable in the development of glyco-nucleic acid constructs and other bioconjugation applications. -
Nucleoside Analog
3'-O-Phthalimido-2'-dA is a nucleoside analog that serves as a versatile monomeric substrate in nucleic acid synthesis. Its structural modifications facilitate the incorporation of modified nucleotides into oligonucleotides, enhancing their stability and functionality. This reagent is essential for applications in molecular biology, particularly in the design and development of oligonucleotide-based therapeutics and probes.
