Catalog No.
Product Name
Application
Product Information
Citations
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Purine Nucleoside Analog
5-(2-Hydroxyethyl)-2'-deoxyuridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanism involves the inhibition of DNA synthesis, leading to cell cycle arrest and the induction of apoptosis in cancer cells. This compound is valuable for research into therapeutic strategies targeting malignancies and understanding the underlying mechanisms of antitumor efficacy. -
Purine Nucleoside Analog
1,2-Di-O-acetyl-3-azido-3-deoxy-5-O-(4-methyl)benzoyl-D-ribofuranose is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms involve the inhibition of DNA synthesis and the induction of apoptotic pathways. Additionally, this compound serves as a versatile click chemistry reagent, thanks to its azide functionality, allowing for copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups. This dual utility broadens its applicability in chemical biology and medicinal chemistry research. -
Purine Nucleoside Analog
DMTr-dH2U-amidite is a purine nucleoside analog that primarily targets DNA synthesis. Its biological activity includes the induction of apoptosis and the inhibition of cell proliferation, making it a valuable tool in cancer research. This reagent is particularly relevant for studying indolent lymphoid malignancies and exploring therapeutic strategies in oncology. -
Purine Nucleoside Analog
(2R-cis)-5-[Tetrahydro-5-(hydroxymethyl)-4-oxo-2-furanyl]-2,4(1H,3H)-pyrimidinedione functions as a purine nucleoside analog, demonstrating significant antitumor activity, particularly against indolent lymphoid malignancies. This compound exhibits its anticancer effects through mechanisms such as the inhibition of DNA synthesis and the induction of apoptosis. It is a valuable tool for research applications aiming to investigate therapies for lymphoid cancers and related diseases. -
Purine Nucleoside Analog
5'-Azido-5'-deoxy-2'-O-(2-methoxyethyl)-5-methyluridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms involve the inhibition of DNA synthesis and the induction of apoptosis. Additionally, this compound functions as a click chemistry reagent due to its azide group, allowing it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. It can also engage in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with entities possessing DBCO or BCN groups, making it a versatile tool for chemical biological research. -
Purine Nucleoside Analog
5-Bromo-2',3',5'-tri-O-acetyluridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis in cancer cells, making it a valuable tool for cancer research. This compound is suitable for studies aimed at understanding the effects of nucleoside analogs in therapeutic applications. -
Pyrimidine Nucleoside Analog
4-Chloro-7-(2-deoxy-β-D-erythro-pentofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine functions as a pyrimidine nucleoside analog. This compound exhibits significant biological activity, including the inhibition of DNA and RNA synthesis, as well as antiviral and immunomodulatory effects. It is applicable in biochemical research and cancer studies, providing insights into nucleic acid metabolism and potential therapeutic pathways. -
Purine Nucleoside Analog
3’-Deoxy-N6,N6-dimethyladenosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary biological actions include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research. This compound is applicable in studies focused on therapeutic strategies targeting nucleoside metabolism and cell proliferation in cancer cells. -
Purine Nucleoside Analog
5’-O-DMTr-5-iodo-2’-dU-3’-CED phosphoramidite functions as a purine nucleoside analog. It exhibits substantial antitumor activity, particularly against indolent lymphoid malignancies, by inhibiting DNA synthesis and inducing apoptosis. This reagent is suitable for research applications focused on cancer therapeutics and the study of nucleic acid interactions in cellular processes. -
Pyrimidine Nucleoside Analog
7-(2-Deoxy-β-D-erythro-pentofuranosyl)-5-fluoro-7H-pyrrolo[2,3-d]pyrimidin-4-amine is a pyrimidine nucleoside analog known for its ability to inhibit DNA and RNA synthesis. This compound exhibits significant biological activities, including antiviral properties and immunomodulation. It is valuable for research applications in cancer therapeutics and virology, providing insights into nucleic acid metabolism and cellular responses. -
Purine Nucleoside Analog
N4-Benzoyl-5’-O-DMTr-2’-O-(N3-trifluoroacetyl) aminopropyl cytidine is a purine nucleoside analog. It exhibits significant antitumor activity, particularly against indolent lymphoid malignancies, through mechanisms such as DNA synthesis inhibition and apoptosis induction. This compound is valuable for research in cancer biology, offering insights into therapeutic strategies targeting nucleoside metabolism and DNA replication processes. -
Adenosine Analog
4’-C-Methyl-N6-methyladenosine is an adenosine analogue that primarily targets adenosine receptors. This compound exhibits significant biological activity as a vasodilator, promoting smooth muscle relaxation, and has shown potential in inhibiting cancer cell progression. It serves as a valuable tool in research applications focused on vascular biology and cancer therapeutics. -
Purine Nucleoside Analog
N1-Allylpseudouridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research and therapeutic applications. Researchers can leverage its properties to explore therapeutic strategies for treating various malignancies. -
Purine Nucleoside Analog
5’-Azido-5’-deoxy-2’-O-(2-methoxyethyl)uridine is a purine nucleoside analog that exhibits broad antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action involve the inhibition of DNA synthesis and the induction of apoptosis. This compound also serves as a click chemistry reagent, featuring an azide group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing alkyne groups or DBCO/BCN moieties. These properties make it a valuable tool for research in chemical biology and medicinal chemistry. -
Purine Nucleoside Analog
2'-O-Hexadecanyl guanosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer effects are primarily attributed to the inhibition of DNA synthesis and the induction of apoptosis. This compound is valuable for research applications focused on cancer biology and therapeutics targeting nucleoside metabolism. -
Purine Nucleoside Analog
2-Chloro-N6-methyl-2’-deoxyadenosine is a purine nucleoside analog that demonstrates significant antitumor activity against indolent lymphoid malignancies. This compound exerts its anticancer effects primarily through the inhibition of DNA synthesis and the induction of apoptosis in cancer cells. It serves as a valuable tool in cancer research, particularly in the study of mechanisms underlying cellular proliferation and programmed cell death. -
Purine Nucleoside Analog
5’-O-(4,4-Dimethoxytrityl)-2’-O-methyl inosine is a purine nucleoside analog that inhibits DNA synthesis and promotes apoptosis in cancer cells. It demonstrates significant antitumor activity, particularly against indolent lymphoid malignancies. This compound serves as a valuable tool in cancer research, facilitating the study of nucleoside metabolism and therapeutic mechanisms in oncological applications. -
Purine Nucleoside Analog
2',3'-Bis-(O-t-butyldimethylsilyl)uridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms involve the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research. This compound is useful in evaluating therapeutic strategies targeting specific malignancies and elucidating the underlying mechanisms of nucleoside metabolism in treated cells. -
Purine Nucleoside Analog
3-O-Benzoyl-1,2:5,6-bis(di-O-isopropylidene)-alpha-D-galactofuranose is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its biological efficacy is primarily mediated through the inhibition of DNA synthesis and the induction of apoptosis. This reagent is valuable for research into cancer therapeutics and the mechanisms of nucleoside analog effects in oncological studies. -
Nucleoside Analog
Rp-ATPαS tetrasodium is a nucleoside analog that serves as a critical substrate in nucleic acid synthesis. This compound is utilized for various biotechnological applications, including the study of RNA synthesis and enzymatic functions in nucleotide metabolism. Its unique properties facilitate research into biochemical pathways and nucleic acid interactions, making it a valuable tool for molecular biology studies. -
Purine Nucleoside Analog
8-Azido-2′-deoxyadenosine is a purine nucleoside analog that exhibits significant antitumor activity. This compound primarily functions by inhibiting DNA synthesis and inducing apoptosis, making it a valuable reagent for research in oncology, particularly in studies targeting indolent lymphoid malignancies. Its unique properties make it a useful tool for investigating cancer cell biology and therapeutic strategies. -
Purine Nucleoside Analog
2-Hydroxy-2'-deoxy-2'-fluoro-beta-D-arabino adenosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanism of action involves the inhibition of DNA synthesis and the induction of apoptosis in cancerous cells. This compound serves as a valuable reagent for research applications focused on cancer biology and therapeutic interventions in lymphoid tumors. -
Purine Nucleoside Analog
2',3',5'-Tri-O-benzoyl-2'-beta-C-methyl-6-azauridine is a purine nucleoside analog that exhibits notable antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research. This compound can be utilized in studies aimed at understanding the therapeutic potential of nucleoside analogs in oncology. -
Purine Nucleoside Analog
3’-O-Methyl-4-deoxy uridine is a purine nucleoside analogue that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanism of action involves the inhibition of DNA synthesis, leading to the induction of apoptosis in cancer cells. This reagent is valuable for research applications focused on cancer biology and therapeutic development. -
Purine Nucleoside Analog
1-(3-β-Azido-2,3-dideoxy-5-O-trityl-D-threopenta-furanosyl)thymine is a purine nucleoside analog that exhibits significant antitumor activity. This compound primarily functions by inhibiting DNA synthesis and inducing apoptosis, making it valuable in the treatment of indolent lymphoid malignancies. Its unique structural properties enable researchers to explore therapeutic applications in cancer biology and nucleic acid metabolism. -
Purine Nucleoside Analog
7,8-Dihydro-8-oxo-7-propargyl-3’-deoxy guanosine is a purine nucleoside analog known for its broad antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanisms involve the inhibition of DNA synthesis and the induction of apoptosis. Additionally, this compound functions as a click chemistry reagent featuring an alkyne group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with azide-containing molecules. This versatility makes it suitable for various applications in chemical biology and drug discovery. -
Purine Nucleoside Analog
6-Methoxy purine-9-beta-D-(3’-deoxy-3’-fluoro)riboside is a purine nucleoside analogue that primarily targets DNA synthesis. This compound exhibits significant antitumor activity, particularly against indolent lymphoid malignancies, through mechanisms such as the inhibition of DNA replication and the induction of apoptosis. Its unique structure allows for diverse applications in cancer research and therapeutic development. -
Adenosine Analog
N6-Isopentenyl-2’-C-methyladenosine is an adenosine analog that primarily acts as a vasodilator by influencing adenosine receptors. This compound has demonstrated potential in inhibiting cancer progression, making it valuable for research in oncology and cardiovascular studies. Its unique structure allows for diverse applications in studying nucleotide metabolism and therapeutic interventions targeting adenosine signaling pathways. -
Nucleoside Analogue
OGT-719 is a potent, orally active nucleoside analogue targeting the asialoglycoprotein receptor (ASGP-R). This compound demonstrates significant inhibition of metastatic colorectal tumor growth in the liver of nude mice. OGT-719 is suitable for research applications focused on primary hepatocellular carcinoma and colorectal liver metastases. -
Purine Nucleoside Analog
4’-Azido-3’-O-benzoyl-5’-O-(m-chlorobenzoyl)-2’-deoxy-2’-fluoro-beta-D-arabinouridine functions as a purine nucleoside analog, demonstrating significant antitumor activity against indolent lymphoid malignancies. Its anticancer mechanisms include the inhibition of DNA synthesis and the induction of apoptosis. Additionally, this compound serves as a versatile click chemistry reagent, featuring an azide group that enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups. This functionality makes it valuable in bioconjugation studies and various chemical biology applications. -
Nucleoside Antimetabolite/Analog
(±)-Lobucavir is a nucleoside antimetabolite/analog known for its carcinogenic activity. Research indicates that chronic administration of (±)-Lobucavir in murine models leads to tumor formation with a similar spectrum to that observed with other nucleoside analogs such as zidovudine or ganciclovir. This compound serves as a valuable tool for studying the mechanisms of nucleoside analog-induced carcinogenesis and their effects in oncological research. -
Purine Nucleoside Analog
6-Chloro-9-(3,5-di-O-benzoyl-2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-9H-purine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer properties are primarily attributed to the inhibition of DNA synthesis and the induction of apoptosis in malignant cells. This compound serves as a valuable tool for research applications focused on oncology and the development of novel therapeutic strategies. -
Purine Nucleoside Analog
3',5'-Di-O-acetyl-2'-deoxy-5,N3-dimethyluridine is a purine nucleoside analog that demonstrates significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms primarily involve the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research. This compound can be utilized in studies aimed at understanding cellular responses to nucleoside analogs and their potential therapeutic effects. -
Purine Nucleoside Analog
5-Amino-2'-deoxyuridine monohydrochloride is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for research in cancer biology and therapeutic development. This compound is applicable in studies focused on nucleic acid metabolism and the exploration of novel cancer treatments. -
Purine Nucleoside Analog
2’-Azido-2’-deoxy-5-methyl cytidine is a purine nucleoside analog with significant antitumor activity, particularly in targeting indolent lymphoid malignancies. Its anticancer effects are primarily mediated through the inhibition of DNA synthesis and the induction of apoptosis. Additionally, this compound serves as a versatile click chemistry reagent, featuring an azide group that enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules that possess DBCO or BCN groups. -
Purine Nucleoside Analog
3’-Deoxy-3’-α-C-methyl-5-fluorouridine is a purine nucleoside analog that primarily targets DNA synthesis. This compound exhibits significant antitumor activity, particularly against indolent lymphoid malignancies, by disrupting nucleotide incorporation into nucleic acids. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research applications. -
Nucleoside Analogue
Methyl 2-deoxy-3,5-di-O-benzoyl-2-fluoro-4-thio-D-arabinopentofuranoside is a ribofuranose nucleoside analogue designed to target nucleoside-dependent pathways. This compound exhibits potential antiviral activity, particularly against certain RNA viruses, and is valuable for research in nucleoside metabolism and therapeutic development. Its structural modifications may enhance stability and bioavailability, making it a useful tool for studying nucleoside interactions and biochemical mechanisms. -
Purine Nucleoside Analog
2’-β-C-Methyl-5-methyluridine is a purine nucleoside analog with significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis. This compound is utilized in research focused on cancer biology and the evaluation of therapeutic strategies targeting nucleoside metabolism. -
Purine Nucleoside Analog
2'-Deoxy-N2,N2-dimethylguanosine is a purine nucleoside analog that exhibits notable antitumor activity, particularly against indolent lymphoid malignancies. Its biological action primarily involves the inhibition of DNA synthesis and the induction of apoptosis in cancer cells. Researchers can utilize this compound in studies focused on cancer biology and the development of therapeutic strategies targeting nucleoside metabolism. -
Purine Nucleoside Analog
2'-Deoxy-N4,N4-dimethylcytidine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanism of action involves the inhibition of DNA synthesis, which promotes apoptosis in cancer cells. This compound is valuable for research applications focused on cancer biology and the development of novel therapeutic strategies. -
Purine Nucleoside Analog
2’-Deoxy-O6-[2-(4-nitrophenylethyl)]guanosine is a purine nucleoside analog that exhibits potent antitumor activity. This compound primarily targets and inhibits DNA synthesis, leading to the induction of apoptosis in cancer cells. It is particularly useful for researching indolent lymphoid malignancies, providing insights into anticancer mechanisms and therapeutic strategies. -
Cytidine Analog
5-Formyl-2’-O-methylcytidine is a cytidine nucleoside analog that acts as an inhibitor of DNA methyltransferases. This compound exhibits potential anti-metabolic and anti-tumor activity, making it a valuable tool in cancer research and epigenetic studies. Its unique structure allows for the investigation of nucleoside metabolism and modifications within nucleic acid processes. -
Cytidine Analog
3’-O-(2-Methoxyethyl)cytidine is a cytidine analog that functions primarily as an inhibitor of DNA methyltransferases. This compound exhibits significant potential in anti-metabolic and anti-tumor research applications, providing a valuable tool for studying epigenetic regulation and cancer biology. Its ability to interfere with DNA methylation processes makes it an important reagent for investigating cellular pathways associated with gene regulation and tumor progression. -
Purine Nucleoside Analog
2’-Amino-2’-deoxy-β-D-arabinouridine is a purine nucleoside analog known for its antitumor activity against indolent lymphoid malignancies. This compound exerts its biological effects primarily through the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research. It is particularly relevant in studies aimed at understanding and developing treatments for specific types of hematological cancers. -
Purine Nucleoside Analog
N6-Methyl-4’-thio-adenosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms involve the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for research in cancer biology and therapeutic development. This reagent is suitable for studies investigating the molecular pathways of cell proliferation and death in malignancies. -
Purine Nucleoside Analog
2’-O-Methyl-2-thiouridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanism involves the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research. This compound is suitable for studies aimed at understanding the molecular pathways of tumor progression and therapeutic responses in malignancies. -
Purine Nucleoside Analog
Purine-9-b-D-(3’,5’-di-O-benzoyl-2’-deoxy-2’-fluoro)arabinoriboside is a purine nucleoside analog that exhibits potent antitumor activity, particularly against indolent lymphoid malignancies. Its mechanism of action involves the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research. This compound is suitable for studies focused on understanding the therapeutic potential of nucleoside analogs in oncology. -
Purine Nucleoside Analog
5'-O-(4,4'-Dimethoxytrityl)-2'-O-methyl-2-thiouridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly in the context of indolent lymphoid malignancies. Its primary mechanisms include the inhibition of DNA synthesis and the induction of apoptosis in cancer cells. This reagent is valuable for research applications in cancer therapy and the study of nucleoside metabolism. -
Purine Nucleoside Analog
1-[6-(Diethoxyphosphinyl)-2-O-methyl-β-D-ribo-hexofuranosyl]uracil is a purine nucleoside analog known for its ability to inhibit DNA synthesis and induce apoptosis in cancer cells. This compound demonstrates broad antitumor activity, particularly against indolent lymphoid malignancies, making it a valuable tool in cancer research. It is useful for studies aimed at understanding mechanisms of action in cancer therapy and for exploring therapeutic pathways involving nucleoside analogs. -
Purine Nucleoside Analog
1-(β-D-Ribofuranosyl)-5-nitropyrine-2(1H)-one is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its biological efficacy is primarily attributed to the inhibition of DNA synthesis and the induction of apoptosis in neoplastic cells. This compound is valuable in cancer research, providing insights into therapeutic strategies targeting purine metabolism and DNA replication pathways.
