Catalog No.
Product Name
Application
Product Information
Citations
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Nucleoside Analogue
OGT-719 is a potent, orally active nucleoside analogue targeting the asialoglycoprotein receptor (ASGP-R). This compound demonstrates significant inhibition of metastatic colorectal tumor growth in the liver of nude mice. OGT-719 is suitable for research applications focused on primary hepatocellular carcinoma and colorectal liver metastases. -
Purine Nucleoside Analog
4’-Azido-3’-O-benzoyl-5’-O-(m-chlorobenzoyl)-2’-deoxy-2’-fluoro-beta-D-arabinouridine functions as a purine nucleoside analog, demonstrating significant antitumor activity against indolent lymphoid malignancies. Its anticancer mechanisms include the inhibition of DNA synthesis and the induction of apoptosis. Additionally, this compound serves as a versatile click chemistry reagent, featuring an azide group that enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups. This functionality makes it valuable in bioconjugation studies and various chemical biology applications. -
Nucleoside Antimetabolite/Analog
(±)-Lobucavir is a nucleoside antimetabolite/analog known for its carcinogenic activity. Research indicates that chronic administration of (±)-Lobucavir in murine models leads to tumor formation with a similar spectrum to that observed with other nucleoside analogs such as zidovudine or ganciclovir. This compound serves as a valuable tool for studying the mechanisms of nucleoside analog-induced carcinogenesis and their effects in oncological research. -
Purine Nucleoside Analog
6-Chloro-9-(3,5-di-O-benzoyl-2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-9H-purine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer properties are primarily attributed to the inhibition of DNA synthesis and the induction of apoptosis in malignant cells. This compound serves as a valuable tool for research applications focused on oncology and the development of novel therapeutic strategies. -
Purine Nucleoside Analog
3',5'-Di-O-acetyl-2'-deoxy-5,N3-dimethyluridine is a purine nucleoside analog that demonstrates significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms primarily involve the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research. This compound can be utilized in studies aimed at understanding cellular responses to nucleoside analogs and their potential therapeutic effects. -
Purine Nucleoside Analog
5-Amino-2'-deoxyuridine monohydrochloride is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for research in cancer biology and therapeutic development. This compound is applicable in studies focused on nucleic acid metabolism and the exploration of novel cancer treatments. -
Uridine Analog
5’-O-DMT-2’-deoxy-2’-fluoro-β-D-arabinouridine is a uridine analog that targets various biological pathways associated with nucleoside metabolism. This compound exhibits potential antiepileptic effects, making it valuable for research in anticonvulsant and anxiolytic activities. Additionally, its unique structure facilitates the exploration of novel antihypertensive agents, contributing to advancements in therapeutic development. -
Uridine Analog
3′,5′-Di-O-acetyl-2′-deoxy-2′-fluorouridine is a uridine analog that serves as a valuable tool for investigating antiepileptic mechanisms. This compound has been shown to possess anticonvulsant and anxiolytic properties, making it useful in the exploration of new therapeutic pathways. Additionally, its structural modifications contribute to the development of novel antihypertensive agents, facilitating research in cardiovascular pharmacology. -
Nucleoside
L-5-Methyluridine is a nucleoside with significant biological relevance, serving as an endogenous methylated form prevalent in human fluids. Its unique structure contributes to various cellular processes, including modulation of RNA stability and translation. This compound is utilized in research exploring RNA function and methylation patterns, making it a valuable reagent for studies related to gene expression and regulation. -
Purine Nucleoside Analog
2’-Azido-2’-deoxy-5-methyl cytidine is a purine nucleoside analog with significant antitumor activity, particularly in targeting indolent lymphoid malignancies. Its anticancer effects are primarily mediated through the inhibition of DNA synthesis and the induction of apoptosis. Additionally, this compound serves as a versatile click chemistry reagent, featuring an azide group that enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules that possess DBCO or BCN groups. -
Purine Nucleoside Analog
3’-Deoxy-3’-α-C-methyl-5-fluorouridine is a purine nucleoside analog that primarily targets DNA synthesis. This compound exhibits significant antitumor activity, particularly against indolent lymphoid malignancies, by disrupting nucleotide incorporation into nucleic acids. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research applications. -
Anticancer Agent
Fosfluridine Tidoxil is an oral-active anticancer agent that utilizes a specific carrier molecule linked by a phosphate group to 5-Fluorouridine (5-FUrd), a metabolite of 5-Fluorouracil (5-FU). This compound demonstrates significant cytotoxic activity against various cancer cell lines, making it a valuable tool in cancer research. Fosfluridine Tidoxil is primarily applied in studies focusing on targeted cancer therapies and the exploration of drug metabolism and efficacy. -
Nucleoside Analogue
Methyl 2-deoxy-3,5-di-O-benzoyl-2-fluoro-4-thio-D-arabinopentofuranoside is a ribofuranose nucleoside analogue designed to target nucleoside-dependent pathways. This compound exhibits potential antiviral activity, particularly against certain RNA viruses, and is valuable for research in nucleoside metabolism and therapeutic development. Its structural modifications may enhance stability and bioavailability, making it a useful tool for studying nucleoside interactions and biochemical mechanisms. -
Purine Nucleoside Analog
2’-β-C-Methyl-5-methyluridine is a purine nucleoside analog with significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis. This compound is utilized in research focused on cancer biology and the evaluation of therapeutic strategies targeting nucleoside metabolism. -
Purine Nucleoside Analog
2'-Deoxy-N2,N2-dimethylguanosine is a purine nucleoside analog that exhibits notable antitumor activity, particularly against indolent lymphoid malignancies. Its biological action primarily involves the inhibition of DNA synthesis and the induction of apoptosis in cancer cells. Researchers can utilize this compound in studies focused on cancer biology and the development of therapeutic strategies targeting nucleoside metabolism. -
Purine Nucleoside Analog
2'-Deoxy-N4,N4-dimethylcytidine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanism of action involves the inhibition of DNA synthesis, which promotes apoptosis in cancer cells. This compound is valuable for research applications focused on cancer biology and the development of novel therapeutic strategies. -
Purine Nucleoside Analog
2’-Deoxy-O6-[2-(4-nitrophenylethyl)]guanosine is a purine nucleoside analog that exhibits potent antitumor activity. This compound primarily targets and inhibits DNA synthesis, leading to the induction of apoptosis in cancer cells. It is particularly useful for researching indolent lymphoid malignancies, providing insights into anticancer mechanisms and therapeutic strategies. -
Cytidine Analog
5-Formyl-2’-O-methylcytidine is a cytidine nucleoside analog that acts as an inhibitor of DNA methyltransferases. This compound exhibits potential anti-metabolic and anti-tumor activity, making it a valuable tool in cancer research and epigenetic studies. Its unique structure allows for the investigation of nucleoside metabolism and modifications within nucleic acid processes. -
Steroid Metabolite
17-Deoxycortolone is a steroid metabolite that serves as a crucial intermediate in steroidogenesis. It is involved in the biosynthesis of corticosteroids and plays a role in various biological processes. This reagent is primarily utilized in biochemical research focusing on steroid metabolism and endocrine function. -
Guanylate Kinases Inhibitor
Guanosine 3',5'-bisdiphosphate (ppGpp) acts as a specific inhibitor of guanylate kinases, affecting GTP biosynthesis in chloroplasts. By inhibiting plastid and mitochondrial guanylate kinase activity, ppGpp is crucial for understanding metabolic regulation and signaling processes in plant systems. This reagent is valuable for research applications involving nucleotide metabolism and signaling pathways. -
Cytidine Analog
3’-O-(2-Methoxyethyl)cytidine is a cytidine analog that functions primarily as an inhibitor of DNA methyltransferases. This compound exhibits significant potential in anti-metabolic and anti-tumor research applications, providing a valuable tool for studying epigenetic regulation and cancer biology. Its ability to interfere with DNA methylation processes makes it an important reagent for investigating cellular pathways associated with gene regulation and tumor progression. -
Phosphonic Acid
2-Methylaminoethylphosphonic acid is a naturally occurring phosphonic acid that acts as a key metabolite in various marine organisms. It has been implicated in neurotransmitter regulation and cellular signaling pathways. This compound serves as a valuable research tool in studying biological processes related to phosphonates, neurobiology, and marine biochemistry. -
Purine Nucleoside Analog
2’-Amino-2’-deoxy-β-D-arabinouridine is a purine nucleoside analog known for its antitumor activity against indolent lymphoid malignancies. This compound exerts its biological effects primarily through the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research. It is particularly relevant in studies aimed at understanding and developing treatments for specific types of hematological cancers. -
Nucleoside Metabolite
2,3-Dihydroxyindole is a nucleoside metabolite that plays a crucial role in various biochemical processes. This compound is known for its potential involvement in melanin biosynthesis and exhibits antioxidant properties. Research applications include studies on pigment formation and its implications in skin biology and related disorders. -
Purine Nucleoside Analog
N6-Methyl-4’-thio-adenosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms involve the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for research in cancer biology and therapeutic development. This reagent is suitable for studies investigating the molecular pathways of cell proliferation and death in malignancies. -
Purine Nucleoside Analog
2’-O-Methyl-2-thiouridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanism involves the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research. This compound is suitable for studies aimed at understanding the molecular pathways of tumor progression and therapeutic responses in malignancies. -
Purine Nucleoside Analog
Purine-9-b-D-(3’,5’-di-O-benzoyl-2’-deoxy-2’-fluoro)arabinoriboside is a purine nucleoside analog that exhibits potent antitumor activity, particularly against indolent lymphoid malignancies. Its mechanism of action involves the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research. This compound is suitable for studies focused on understanding the therapeutic potential of nucleoside analogs in oncology. -
Purine Nucleoside Analog
5'-O-(4,4'-Dimethoxytrityl)-2'-O-methyl-2-thiouridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly in the context of indolent lymphoid malignancies. Its primary mechanisms include the inhibition of DNA synthesis and the induction of apoptosis in cancer cells. This reagent is valuable for research applications in cancer therapy and the study of nucleoside metabolism. -
Microbial Metabolite
Beta-alanyl-L-arginine is an intestinal microbial metabolite that plays a significant role in neurotransmission. This compound has been identified as useful in the investigation of schizophrenia, providing insights into its potential metabolic pathways and relationship with gut-brain interactions. Researchers may explore its effects on neurochemical signaling, offering a novel avenue for understanding psychiatric disorders. -
Fatty Acid
8(Z),11(Z),14(Z)-Heptadecatrienoic acid, also known as Norlinolenic acid, is a fatty acid comprised of three double bonds. This compound is recognized for its potential bioactivity in modulating lipid metabolism and promoting anti-inflammatory pathways. It serves as a valuable reagent in biochemical research focusing on fatty acid metabolism, lipidomics, and the exploration of dietary fats' effects on health. -
Purine Nucleoside Analog
1-[6-(Diethoxyphosphinyl)-2-O-methyl-β-D-ribo-hexofuranosyl]uracil is a purine nucleoside analog known for its ability to inhibit DNA synthesis and induce apoptosis in cancer cells. This compound demonstrates broad antitumor activity, particularly against indolent lymphoid malignancies, making it a valuable tool in cancer research. It is useful for studies aimed at understanding mechanisms of action in cancer therapy and for exploring therapeutic pathways involving nucleoside analogs. -
Purine Nucleoside Analog
1-(β-D-Ribofuranosyl)-5-nitropyrine-2(1H)-one is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its biological efficacy is primarily attributed to the inhibition of DNA synthesis and the induction of apoptosis in neoplastic cells. This compound is valuable in cancer research, providing insights into therapeutic strategies targeting purine metabolism and DNA replication pathways. -
Guanosine Analog
8-(Phenylmethoxy)guanosine is a guanosine analog that exhibits immunostimulatory activity. This compound has been shown to induce type I interferons in various animal models, thereby providing antiviral effects. The biological activity of this guanosine analog is closely linked to the activation of Toll-like receptor 7 (TLR7), making it a valuable tool for research into antiviral mechanisms and immune response modulation. -
Purine Nucleoside Analog
1-Methyl-2'-O-methylinosine is a purine nucleoside analog that exhibits broad antitumor activity. This compound primarily targets indolent lymphoid malignancies and functions by inhibiting DNA synthesis and inducing apoptosis. It serves as a valuable tool in cancer research, aiding in the exploration of therapeutic approaches to treat various malignancies. -
Purine Nucleoside Analog
3’-Deoxy-3’-fluoro-5-methoxyluridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanism involves the inhibition of DNA synthesis, which can lead to the induction of apoptosis in cancer cells. This compound is valuable for research applications focused on cancer therapeutics and elucidating the molecular mechanisms underlying tumorigenesis. -
Purine Nucleoside Analog
3',5'-Di-O-benzoyl fialuridine is a purine nucleoside analog that exhibits potent antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanism involves the inhibition of DNA synthesis, leading to cell cycle arrest and subsequent induction of apoptosis. This compound is valuable for research into therapeutic strategies targeting malignancies and understanding nucleoside analog mechanisms in cancer treatment. -
Nucleoside Metabolite
2-Methoxy-estradiol-17beta 3-glucuronide is a nucleoside metabolite known for its role in estradiol metabolism. This compound exhibits potential anti-proliferative activity and may influence estrogen signaling pathways. It is primarily used in research related to estrogen-related cancers, reproductive biology, and the study of glucuronidation processes. -
Purine Nucleoside Analog
3’-O-Levulinyl-2’-deoxyadenosine is a purine nucleoside analog that serves as an effective agent in anticancer research. It possesses significant antitumor activity, particularly against indolent lymphoid malignancies, through mechanisms that include DNA synthesis inhibition and apoptosis induction. This compound is valuable for studies focused on cancer therapeutics and mechanisms of action in malignant cell lines. -
Purine Nucleoside Analog
2'-Bromo-2'-deoxy-5-methyluridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanism involves the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research. This compound can be utilized to explore therapeutic strategies and pathways associated with tumorigenesis and cellular proliferation. -
Carboxysterol
4α-Carboxy-stigmasta-7,24(24(1))-dien-3β-ol is a carboxysterol that functions primarily as a bioactive sterol molecule. This compound exhibits significant biological activities, influencing lipid metabolism and cellular signaling pathways. It has applications in research focused on cholesterol biosynthesis, cardiovascular health, and the modulation of sterol-related diseases. -
Purine Nucleoside Analog
5’(R)-C-Methyladenosine is a purine nucleoside analogue that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research. This compound serves as a useful reagent for studying the effects of nucleoside analogs in therapeutic contexts. -
Purine Nucleoside Analog
2-Chloro-3′-deoxyadenosine is a purine nucleoside analog that primarily targets DNA synthesis. It exhibits significant antitumor activity, particularly against indolent lymphoid malignancies, by inhibiting cellular proliferation and inducing apoptosis. This compound serves as an important tool in cancer research, providing insights into therapeutic approaches for hematologic malignancies. -
Purine Nucleoside Analog
2′-Deoxy-6-thioinosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanism of action includes the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool in cancer research. This compound is useful for investigating the pathways involved in tumor cell proliferation and survival. -
Purine Nucleoside Analog
8-Benzyloxy-3’-deoxy-3’-fluoroguanosine is a purine nucleoside analog that exerts notable antitumor activity against indolent lymphoid malignancies. Its mechanism of action involves the inhibition of DNA synthesis and the induction of apoptosis in cancer cells. This compound is valuable for research focused on oncological studies, particularly in understanding the pathways of cancer cell proliferation and response to nucleoside-based therapies. -
Guanosine Analog
N2-iso-Butyroyl-7'-O-DMT-morpholinoguanine is a guanosine analog that primarily targets Toll-like receptor 7 (TLR7). This compound exhibits immunostimulatory activity and has been shown to induce type I interferons in various animal models, leading to antiviral effects. It serves as a valuable reagent for research applications focused on innate immunity and the modulation of antiviral responses. -
Purine Nucleoside Analog
3’-Deoxy-3’-α-C-methylguanosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis in cancer cells. This compound is valuable for research applications focused on cancer biology and therapeutic development targeting purine metabolism. -
Purine Nucleoside Analog
3’-Deoxy-5’-O-(4,4’-dimethoxytrityl)-3’-fluorouridine is a purine nucleoside analog with significant potential in cancer research. It exhibits broad antitumor activity, particularly against indolent lymphoid malignancies, by inhibiting DNA synthesis and inducing apoptotic pathways. This compound can be utilized in studies focused on cancer therapeutics and the mechanisms underlying nucleoside analog efficacy in oncological contexts. -
Purine Nucleoside Analog
2'-Deoxy-2'-fluoro-N4-benzoyl-5-methylcytidine is a purine nucleoside analog that showcases significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanism involves the inhibition of DNA synthesis, leading to apoptosis in cancerous cells. This compound serves as an essential tool for research in oncology, aiding in the exploration of novel therapeutic strategies targeting nucleic acid synthesis pathways. -
Purine Nucleoside Analog
1,3-Dimethyl pseudouridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanisms include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable reagent for cancer research. This compound is utilized in studies aimed at understanding cancer therapies and developing new treatments targeting nucleoside pathways. -
Purine Nucleoside Analog
7,8-Dihydro-8-oxo-7-propargyl guanosine is a purine nucleoside analog known for its antitumor activity, particularly against indolent lymphoid malignancies. This compound exerts its anticancer effects through mechanisms such as DNA synthesis inhibition and apoptosis induction. Additionally, it serves as a click chemistry reagent due to its alkyne group, enabling copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules, facilitating advanced bioconjugation applications.
