2’-Azido-2’-deoxy-5-methyl cytidine is a purine nucleoside analog with significant antitumor activity, particularly in targeting indolent lymphoid malignancies. Its anticancer effects are primarily mediated through the inhibition of DNA synthesis and the induction of apoptosis. Additionally, this compound serves as a versatile click chemistry reagent, featuring an azide group that enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules that possess DBCO or BCN groups.
2’-Azido-2’-deoxy-5-methyl cytidine is a purine nucleoside analog with significant antitumor activity, particularly in targeting indolent lymphoid malignancies. Its anticancer effects are primarily mediated through the inhibition of DNA synthesis and the induction of apoptosis. Additionally, this compound serves as a versatile click chemistry reagent, featuring an azide group that enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules that possess DBCO or BCN groups.
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