Fig. 1 · Structure

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2’-O-Methyl-2-thiouridine

Purine Nucleoside Analog

2’-O-Methyl-2-thiouridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanism involves the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research. This compound is suitable for studies aimed at understanding the molecular pathways of tumor progression and therapeutic responses in malignancies.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 113886-72-9
Applications Purine Nucleoside Analog
Formula C10H14N2O5S
Molecular Weight 274.29
SMILES
OC[C@@H]1[C@@H](O)[C@@H](OC)[C@H](N2C(NC(C=C2)=O)=S)O1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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