Catalog No.
Product Name
Application
Product Information
Citations
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Fluorescent Dye
SIMA phosphoramidite, 6-isomer, is a xanthene-based fluorescent dye exhibiting spectral properties comparable to HEX, combined with an enhanced quantum yield. This compound demonstrates superior stability during deprotection in alkaline environments, making it an ideal choice for applications in nucleic acid labeling and fluorescent assays. Its robust performance enables reliable detection in various research settings. -
Fluorescent Dye
BP Fluor 532 NHS ester is an amine-reactive fluorescent dye designed for labeling biomolecules, particularly proteins and antibodies, through primary amines. It exhibits bright yellow fluorescence and maintains stable emission across a wide pH range (4 to 10), making it suitable for diverse biological applications. The dye forms a stable covalent amide bond, with optimal labeling efficiency achieved at pH 7-9. BP Fluor 532 is compatible with frequency-doubled Nd:YAG laser excitation and is widely utilized in imaging techniques and flow cytometry to enhance signal stability. -
Fluorescent Dye
DMT-BH2 amidite is a black quencher dye designed for the synthesis of dual-labeled oligonucleotide probes with a 5'-quencher suitable for quantitative PCR (qPCR). This amidite effectively quenches fluorophores such as HEX, JOE, ROX, and Cyanine5, making it optimal for applications involving emissions in the orange and red regions of the spectrum. Its selective quenching properties enhance the sensitivity and specificity of nucleic acid detection assays. -
Fluorescein Dye
Fluorescein hydrazide (3,6-Dihydroxyxanthane) is a fluorescein dye that primarily targets reactive oxygen species (ROS) such as hydrogen peroxide (H2O2). This compound exhibits strong fluorescence properties, making it suitable for fluorophotometric assays in various biological studies. It is widely used in research applications focused on oxidative stress, cellular signaling, and ROS detection. -
Fluorescent Dye
2-Amino-5-methoxybenzamidoxime is a fluorescent dye utilized for the detection of various ketones, such as aromatic, hydroxyl, cyclic, and aliphatic ketones. This compound exhibits distinct fluorescence properties, with an excitation maximum at 389 nm and an emission maximum at 515 nm, making it suitable for applications in analytical chemistry and biochemistry for visualizing and quantifying ketone compounds. Its sensitivity and specificity make it an effective tool for researchers studying ketone-related biochemical processes. -
Fluorescent Dye
PSP is a two-photon fluorescent probe designed for the selective and sensitive detection of hydrogen sulfide (H2Sn) in live cells and tumor spheroids, with excitation and emission wavelengths of 440 nm and 640 nm, respectively. This reagent is particularly valuable in ferroptosis research, enabling real-time monitoring of reactive sulfur species within biological systems. Its high selectivity and sensitivity make PSP an essential tool for studying cellular pathways and mechanisms associated with oxidative stress and cell death. -
Potassium Fluorescent Indicator
Asante Potassium Green-1 (TMA) is a cell-impermeable fluorescent indicator designed to selectively detect potassium ions (K+) with an excitation wavelength of 525 nm and emission wavelength of 545 nm. This compound allows researchers to monitor intracellular potassium levels with high sensitivity and specificity, making it invaluable for studies involving ion transport, cellular signaling, and physiology. Its utility in real-time fluorescence imaging facilitates investigations into potassium's role in various biological processes and disease states. -
Potassium Fluorescent Indicator
Asante potassium green-1 AM is a cell-permeable potassium (K+) sensitive fluorescent indicator with an excitation/emission wavelength of 525/545 nm. This reagent enables the visualization and quantification of potassium ion fluctuations within live cells, making it suitable for studies in neurobiology, cardiac research, and cellular signaling. Its high sensitivity to K+ concentrations facilitates investigations into ion channel activity and cellular excitability, enhancing understanding of various physiological processes. -
Fluorescent Dye
Sulfo-QSY21-NHS is a fluorescent dye featuring an N-hydroxysuccinimide (NHS) moiety that readily reacts with amine groups (-NH2) present in proteins and other biomolecules, resulting in stable amide bond formation. This compound is commonly utilized in the synthesis of activity-based probes (ABPs), facilitating the study of enzyme activity and protein interactions in various biological research applications. Its robust fluorescent properties make it an ideal choice for high-sensitivity detection methods in biochemical assays. -
Azo Dye
Disperse Red 343 is an azo dye that primarily targets polyester fibers, functioning as a dyeing agent in textile applications. It exhibits strong color fastness properties, making it ideal for use in synthetic fabric coloration. Research applications may include studies on dye absorption, migration, and the environmental impact of azo dye usage in textile manufacturing processes. -
Azo Dye
Disperse Red 153 is an azo dye characterized by its vibrant red color and application in various industries. This compound demonstrates excellent compatibility with plastics and textiles, making it suitable for coloring applications in these materials. Additionally, its stability and non-volatile properties extend its utility to cosmetic formulations. -
K+ Fluorescent Indicator
IPG-2 AM is a membrane-permeable potassium (K+) fluorescent indicator. This reagent is designed to enable the detection and quantification of intracellular potassium ion concentrations in live cells through fluorescence microscopy. Its application is crucial in studies related to ion channel activity, cellular signaling, and neuronal function. -
GA Fluorescent Probe
AIE-GA is a fluorescent probe designed to target the Golgi apparatus, emitting fluorescence in the green channel with excitation at 405 nm and an emission range of 500-700 nm. This probe exhibits favorable binding affinity to cyclooxygenase-2 (COX-2), specifically interacting with its catalytic site. AIE-GA serves as a valuable tool for cellular imaging and studies involving the Golgi apparatus and COX-2, facilitating research in inflammation and related pathways. -
Fluorescent Probe
MIT-PZR is a mitochondria-targeted fluorescent probe designed for effective imaging applications. With low cytotoxicity, it is suitable for use in live-cell experiments and in vivo imaging studies. This probe exhibits excitation and emission maxima at 485 nm and 705 nm, respectively, enabling the visualization of mitochondrial activity and dynamics in real-time. -
Fluorescent Dye
Mito-CCY is a mitochondria-targeted fluorescent dye characterized by its near-infrared (NIR) absorption properties. This cryptocyanine probe exhibits high photothermal conversion efficiency and demonstrates good biological compatibility in vitro. Additionally, Mito-CCY induces photoinduced cytotoxicity in HeLa cells, making it a valuable tool for studies in mitochondrial dynamics and photothermal therapy applications. -
Fluorescent Dye
CellTracker Orange CMRA Dye is a fluorescent dye designed for cellular imaging and monitoring. It allows for the visualization of cellular movement and localization, providing insights into cell dynamics and behavior. This reagent is particularly useful in studies requiring tracking of live cells in a variety of biological contexts. -
Dye
7-Methoxycoumarin-3-carboxylic acid serves as a precursor for the synthesis of hydrophilic dye compounds. The resultant dye demonstrates a uniform distribution within cellular environments, making it an effective probe for assessing viscosity in the cytoplasm. This compound is valuable for various applications in cellular imaging and biophysical studies. -
pH Indicator Dye
m-Cresol purple is a pH indicator dye that exhibits halochromic properties, allowing for a clear visual transition in the neutral pH range. Its large cross-section enhances its sensitivity, making it an effective tool for monitoring pH changes in various biochemical assays. This compound is commonly utilized in laboratory settings for applications such as titrations, biological studies, and environmental analyses. -
Dye
Propyl Red is a versatile dye primarily used for biological staining. This compound facilitates the observation and analysis of cellular structures, enables biomolecule tracking, and assists in the evaluation of cell functions, making it valuable in both basic and clinical research applications. Additionally, Propyl Red is utilized for distinguishing cell types, detecting biomolecules, studying tissue pathology, and monitoring microorganisms. Beyond its biological uses, it finds applications in traditional textile dyeing and emerging technologies, including functional textiles and dye-sensitized solar cells. -
Fluorescent Substrate
Nicotinamide 1,N6-ethenoadenine dinucleotide (ε-NAD) acts as a fluorescent substrate with significant utility in biochemical research. This analog of NAD can be cleaved by phosphodiesterase I, sourced from C. adamanteus venom, and demonstrates binding affinity to bovine liver glutamate dehydrogenase. It serves as a substrate for G-ADP ribosylation of G proteins, a process facilitated by bacterial toxins, making it valuable for investigating ADP ribosylation reactions. Its fluorescent properties enhance detection and analysis in experimental applications. -
Calcium-binding Fluorescent Dye
Alizarin complexone is a calcium-binding fluorescent dye that specifically targets calcium crystals within mineralized areas of bone. This compound demonstrates notable antiviral activity, inhibiting reverse transcriptase activity in RAV-2, HIV-1, and RSV with IC50 values of 3.8 μg/mL, 45 μg/mL, and 100 μg/mL, respectively. In addition, Alizarin complexone has been shown to delay RSV-induced tumor induction in chicken models, making it valuable for research in virology and studies of calcium dynamics in mineralization processes. -
ACE-I Fluorescent Substrate
Abz-Gly-p-nitro-Phe-Pro-OH is a fluorescent substrate specific for angiotensin I converting enzyme (ACE-I), facilitating the study of enzyme kinetics and activity. The compound exhibits excitation at 355 nm and emission at 405 nm, making it suitable for high-sensitivity fluorescence assays. This substrate can be utilized in research applications focused on cardiovascular biology, hypertension, and related signaling pathways. -
GPR55 Fluorescent Ligand
Tocrifluor 1117 is a selective fluorescent ligand targeting the GPR55 receptor. This compound serves as a valuable tool in research for visualizing the cellular distribution of cannabinoid receptors, including GPR55, in live tissues. With excitation and emission maxima at 543 nm and 590 nm, respectively, Tocrifluor 1117 enhances the understanding of cannabinoid receptor localization and function in various biological contexts. -
Nitrite Dye
Calcium phosphorylcholine chloride (98%) is a key phospholipid component found in eukaryotic biofilms. This compound is present in both commensal and pathogenic bacteria associated with eukaryotes, contributing to their structural integrity. It demonstrates a notable range of immunomodulatory properties, making it valuable for research applications that explore immune responses and microbial interactions. -
Acidic Dye
Acid Blue 129 is an acidic dye with a selective antagonistic effect on the P2Y receptor in guinea pig taenia coli, demonstrating its utility in biological research related to purinergic signaling. This compound does not interact with the P2X receptor in rat vas deferens, highlighting its specificity. Additionally, Acid Blue 129 is suitable for dyeing various materials, including cotton, wool, silk, nylon, paper, and leather, making it versatile for both scientific and industrial applications. -
Anthraquinone Dye
Flavokermesic acid is an anthraquinone dye primarily found in extracts of the Diaspididae family of insects. It serves as a valuable tool for studying the biosynthetic pathways associated with insect-derived anthraquinone pigments, contributing to insights into pigment production and its biological significance. This compound is utilized in various research applications focused on natural product chemistry and insect biology. -
Fluorescent Dye
Biotin (5-fluorescein) conjugate is a fluorescently labeled biotin derivative designed for effective cell labeling. This compound exhibits high biological activity in detecting and localizing target molecules in various biomedical research applications. It is particularly useful in immunofluorescence staining experiments, enhancing both sensitivity and specificity in the visualization of biomolecular interactions. -
Fluorescent Dye
PDAM (1-Pyrenyldiazomethane) is a fluorescent dye known for its strong biomarker properties and fluorescence activity. It is utilized in cell imaging for histological studies, allowing for clear delineation of specific cell structures. Additionally, PDAM serves as a hematological stain, enhancing the visualization of cellular components to facilitate more accurate diagnoses in various research applications. -
Fluorescent Peptide
Boc-Ile-Glu-Gly-Arg-AMC is a fluorogenic peptide substrate specifically designed for the activated factor X (FXa). This compound exhibits key biological activity by enabling the quantification of FXa in various biological assays. It is particularly useful in research applications focused on coagulation, thrombin generation, and related hemostatic studies. -
Fluorescence Dye
Cholylglycylamidofluorescein (CGamF) is a fluorescent probe designed to study hepatic bile acid transport mechanisms. This compound is composed of cholic acid linked through a glycylamino bond to fluorescein, offering a fluorescence excitation/emission maxima at 492/515 nm in aqueous solutions. CGamF is utilized in research applications involving bile acid metabolism and transport processes within liver cells, enabling in-depth studies of hepatic function and pathology. -
Fluorescent Probe
18:1 Liss Rhod PE is a fluorescent phospholipid used as a fluorescent probe. It is highly effective for monitoring dip-pen nanolithography-generated structures through fluorescence microscopy, facilitating large-scale imaging of phospholipid inks. Additionally, 18:1 Liss Rhod PE exhibits phase separation and self-quenching behavior under specific conditions in thin lipid membrane stacks, making it valuable for studies of membrane dynamics and organization. -
Dye Reagents
HB-230 is a red fluorescent probe designed specifically for transglutaminase 2 (TG2). It effectively binds to TG2 and α2-macroglobulin through the LRP1 pathway, facilitating efficient endocytosis. HB-230 exhibits excitation and emission wavelengths of 649 nm and 665 nm, respectively, making it suitable for imaging applications in studies involving TG2. This reagent is valuable for researchers investigating cellular processes associated with TG2 activity. -
Fluorescent Substrate
4-Methylumbelliferyl-α-D-Glucopyranoside is a fluorescent substrate targeting α-glucosidase, which releases the fluorescent moiety 4-methylumbelliferyl (4-MU) upon enzymatic cleavage. This compound exhibits pH-dependent fluorescence, with excitation wavelengths of 320 nm in acidic conditions and 360 nm in alkaline conditions, while its emission increases between 445-455 nm as pH decreases. 4-Methylumbelliferyl-α-D-Glucopyranoside serves as a valuable biomarker for assessing α-glucosidase activity in infant blood spot samples, particularly in the context of Fabry and Pompe diseases. -
Near-infrared Fluorescent Probe
NIR-BG2 is a near-infrared fluorescent probe that selectively targets senescence-associated β-galactosidase (SA-β-Gal). Upon activation by SA-β-Gal, NIR-BG2 undergoes hydrolysis to release an electrophilic quinone methide, which covalently labels surrounding proteins, resulting in a 16-fold increase in fluorescence intensity at 709 nm. This compound is valuable for in vivo imaging studies focused on cellular senescence, enabling researchers to visualize senescent cells effectively. -
Sigma-2 Receptor Fluorescent Ligand
SW116 free base is a selective fluorescent ligand for the sigma-2 receptor, exhibiting a binding affinity with a Ki value of 14 nM. This compound displays a maximal excitation wavelength of 333 nm and a maximal emission wavelength of 506 nm when dissolved in methanol. SW116 free base can be internalized by MDA-MB-435 cells, achieving 50% maximum fluorescent intensity within 24 minutes. Due to its properties, it serves as a valuable fluorescent probe in cancer research applications. -
Cereblon Protein Fluorescent Probe
BODIPY FL thalidomide is a high-affinity fluorescent probe that targets human cereblon protein, exhibiting a Kd value of 3.6 nM. This compound is utilized in research applications to study cereblon-mediated pathways and drug-protein interactions. Its fluorescent properties facilitate visualization in cellular assays, making it a valuable tool for investigating the roles of cereblon in various biological processes. -
Benzothiazole Dye
BTA-2 is a benzothiazole dye that exhibits enhanced fluorescent signaling when bound to amyloid fibrils. Its unique absorption and emission properties in both solution and fibrillar states make it a valuable tool for identifying amyloid fibrils via spectroscopy. BTA-2 is particularly useful in research applications related to neurodegenerative diseases and the study of protein aggregation. -
Fluorescent Substrate Peptide
Mca-SEVNLDAEFK(Dnp) is a fluorescent substrate peptide specifically designed for the estimation of Beta-secretase 1 (BACE-1) activity. Featuring the 'Swedish' mutation of the amyloid precursor protein (APP) β-secretase cleavage site, this substrate undergoes cleavage at the -Leu-Asp- bond, releasing the highly fluorescent 7-methoxycoumarin (Mca) fragment. This release results in a significant increase in fluorescence intensity due to the removal of the quenching effect from the 2,4-dinitrophenyl (Dnp) moiety, making it a valuable tool for research applications in Alzheimer’s disease and related studies of amyloid pathology. -
fluorescent substrate for BACE1
β-Secretase substrate VI, fluorogenic is a fluorogenic peptide labeled with EDANS and DABCYL, specifically designed for the measurement of β-site amyloid precursor protein cleaving enzyme 1 (BACE1) activity. This substrate enables the quantification of BACE1 enzymatic activity through fluorescence emission (Em=360nm, Ex=528nm), providing a direct correlation between enzyme activity levels and fluorescence intensity. It is an essential tool for researchers studying Alzheimer's disease and related amyloidogenic processes. -
Mitochondria Dye
Methylene Violet 3RAX is a phenazine dye primarily targeting mitochondria for cellular staining. This reagent can alter DNA molecular structure and induce the production of reactive singlet oxygen. It also exhibits inhibitory activity against human erythrocyte acetylcholinesterase (AChE) and human plasma butyrylcholinesterase (BChE) with inhibition constants (Ki) of 1.58 and 0.51 µM, respectively. Methylene Violet 3RAX is valuable for researching potential photosensitizers aimed at mitochondrial targeting in photodynamic therapy (PDT). -
Fluorescent Dye
C.I. Acid Yellow 151 is a fluorescent dye known for its strong adsorption properties. It is commonly used in various biological assays and microscopy applications to visualize cellular components. Additionally, C.I. Acid Yellow 151 can be effectively removed by bentone, making it suitable for various purification processes in chemical research. -
Fluorescent Dye
C.I. Acid Brown 83 is a fluorescent dye that exhibits strong adsorption properties. Its ability to bind and be removed by bentone clay makes it valuable in various analytical and biotechnological applications. This compound is commonly utilized in research involving fluorescence microscopy and dye-binding assays. -
Fluorescent Dye
C.I. Mordant Green 17 is a fluorescent dye characterized by its azo structure. It exhibits strong absorption and fluorescence properties, making it suitable for various biological staining applications. This dye is commonly used in histology and cytology for the visualization of cellular components, enabling researchers to study tissue morphology and cellular interactions effectively. -
Fluorescent Dye
C.I. Disperse Orange 37 is a fluorescent dye that primarily targets textiles and fibers for coloration. This vibrant orange dye exhibits high thermal stability and is frequently employed in the dyeing of synthetic fibers. Its ability to fluoresce under ultraviolet light makes it suitable for various applications in research, including studies on fiber characterization and tracing. -
Fluorescent Dye
Pigment Yellow 73 is a disazomethine dye primarily utilized as a fluorescent marker. This compound exhibits solid-state fluorescence, making it valuable for various biological research applications, including cell imaging and biosensing. Its unique fluorescent properties facilitate the visualization of cellular structures and processes, contributing to advancements in biochemical and molecular biology studies. -
Fluorescent Dye
C.I. Acid Red 138 is a fluorescent dye primarily utilized for its staining properties in various biological applications. It exhibits strong adsorption characteristics, enabling effective removal from different matrices using bentone clay. This compound is valuable in histology, cellular imaging, and as a tracer in biochemical assays, facilitating enhanced visualization and differentiation of biological samples. -
Fluorescent Dye
C.I. Acid Yellow 172 is a fluorescent dye utilized for various biochemical applications. Its acidic properties make it suitable for adsorption processes, particularly in environments involving bentone. This compound is often employed in studies requiring visual tracking or quantification of biological molecules and helps in enhancing the contrast in fluorescent imaging analyses. -
Fluorescent Dye
C.I. Pigment Orange 34 is a fluorescent dye primarily utilized for its exceptional coloring properties. It exhibits stability and consistency when incorporated into various carriers or mediums, making it suitable for applications across diverse industries such as textiles, medicine, food, cosmetics, plastics, paints, inks, photography, and paper products. Its robust performance and versatility make it a vital reagent for researchers seeking reliable colorants in their studies. -
Fluorescent Dye
Pigment Yellow 111 is a disazomethine dye that exhibits solid-state fluorescence. This compound is primarily utilized as a fluorescent dye in various biological research applications, including imaging and labeling of cellular components. Its distinct fluorescent properties make it valuable for studies in fluorescence microscopy and other imaging techniques, enhancing the visualization of biological processes. -
Fluorescent Dye
Fluorescent Brightener 251 is a fluorescent dye known for its ability to enhance optical brightness in a variety of applications. This compound exhibits strong fluorescence properties, making it suitable for use in biological imaging and assays. It is commonly employed in studies requiring fluorescence detection, contributing to improved sensitivity and contrast in visualizing biological specimens.
