• Sign In
  • FAQ
  • Create an Account
Currency
USD currency flagUSD
Toggle Nav
My Cart
Menu
Account
Settings
Currency
USD currency flagUSD

β-Secretase substrate VI, fluorogenic

Catalog No.: A78495
fluorescent substrate for BACE1
β-Secretase substrate VI, fluorogenic is a fluorogenic peptide labeled with EDANS and DABCYL, specifically designed for the measurement of β-site amyloid precursor protein cleaving enzyme 1 (BACE1) activity. This substrate enables the quantification of BACE1 enzymatic activity through fluorescence emission (Em=360nm, Ex=528nm), providing a direct correlation between enzyme activity levels and fluorescence intensity. It is an essential tool for researchers studying Alzheimer's disease and related amyloidogenic processes.
β-Secretase substrate VI, fluorogenic 310427-94-2 fluorescent substrate for BACE1
Grouped product items
Size Stock
5mg
10mg
50mg
Bulk Size
Bulk Discount
Bulk Inquiry
Notify me when the price drops
Notify me when this product is in stock
Free Delivery on orders over $500
Research use only. We do not sell to patients.
Data Sheet SDS

Loading distributor info...

Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Descriptionβ-Secretase substrate VI, fluorogenic is a fluorogenic peptide labeled with EDANS and DABCYL, specifically designed for the measurement of β-site amyloid precursor protein cleaving enzyme 1 (BACE1) activity. This substrate enables the quantification of BACE1 enzymatic activity through fluorescence emission (Em=360nm, Ex=528nm), providing a direct correlation between enzyme activity levels and fluorescence intensity. It is an essential tool for researchers studying Alzheimer's disease and related amyloidogenic processes.
Product Information
Catalog NumA78495
FormulaC91H129N25O25S
Molecular Weight2005.22
CAS Number310427-94-2
SequenceArg-{Glu(EDANS)}-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-{Lys(DABCYL)}-Arg
Sequence shorteningR-{Glu(EDANS)}-EVNLDAEF-{Lys(DABCYL)}-R
SMILESN(CCNC(CC[C@@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC1=CC=CC=C1)C(N[C@H](C(N[C@@H](CCCNC(=N)N)C(O)=O)=O)CCCCNC(=O)C2=CC=C(N=NC3=CC=C(N(C)C)C=C3)C=C2)=O)=O)CCC(O)=O)=O)C)=O)CC(O)=O)=O)CC(C)C)=O)CC(N)=O)=O)C(C)C)=O)CCC(O)=O)=O)NC([C@H](CCCNC(=N)N)N)=O)=O)C=4C5=C(C(S(=O)(=O)O)=CC=C5)C=CC4
SynonymsRE(EDANS)EVNLDAEFK(DABCYL)R
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2

Dyes