SW116 free base is a selective fluorescent ligand for the sigma-2 receptor, exhibiting a binding affinity with a Ki value of 14 nM. This compound displays a maximal excitation wavelength of 333 nm and a maximal emission wavelength of 506 nm when dissolved in methanol. SW116 free base can be internalized by MDA-MB-435 cells, achieving 50% maximum fluorescent intensity within 24 minutes. Due to its properties, it serves as a valuable fluorescent probe in cancer research applications.
SW116 free base is a selective fluorescent ligand for the sigma-2 receptor, exhibiting a binding affinity with a Ki value of 14 nM. This compound displays a maximal excitation wavelength of 333 nm and a maximal emission wavelength of 506 nm when dissolved in methanol. SW116 free base can be internalized by MDA-MB-435 cells, achieving 50% maximum fluorescent intensity within 24 minutes. Due to its properties, it serves as a valuable fluorescent probe in cancer research applications.
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