Catalog No.
Product Name
Application
Product Information
Citations
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Fluorescent Dye
6-JOE, SE is an amine-reactive fluorescent dye designed for the specific labeling of amino-modified oligonucleotides. This reagent enables the sensitive detection and visualization of nucleic acids, facilitating various applications in molecular biology and genomics. Its ability to form stable conjugates makes it an essential tool for researchers involved in DNA and RNA studies. -
Fluorescent Membrane Probe
3-Morpholinobenzanthrone is a fluorescent membrane probe that exhibits a higher dipole moment in its excited state compared to its ground state. This characteristic facilitates its application in cellular imaging, allowing for enhanced visualization of membrane dynamics. The compound is particularly useful in biophysical studies and investigations focused on membrane interactions and behavior. -
Azo Dye
Hydroxy naphthol blue (disodium) is an azo dye utilized primarily as an acid-base indicator, exhibiting a maximum absorbance at 650 nm. This compound demonstrates distinct color changes within the pH range of 12 to 13, appearing pale red in the presence of calcium ions and transitioning to dark blue upon interaction with disodium EDTA. It is valuable in biochemical assays and analytical chemistry for monitoring pH levels and ion concentrations. -
Voltage-Sensitive Dye
RH 795 is a fast-response voltage-sensitive dye that selectively reports on membrane potential changes in biological systems. This compound exhibits high sensitivity and rapid kinetics, making it an essential tool for studying neuronal activity and other excitable cells. It is widely used in electrophysiological research to investigate membrane dynamics and the mechanisms underlying cellular excitability. -
Fluorescent Dye
Zinquin AM ester is a fluorescent dye that serves as a specific sensor for assessing cellular zinc (Zn2+) levels. Its AM ester modification enhances membrane permeability, allowing for effective intracellular staining and visualization of zinc dynamics in live cells. This reagent is widely utilized in studies investigating zinc's role in various biological processes and cellular signaling pathways. -
Fluorescent Dye
Rhodamine B, tetramethyl-, isothiocyanate is a fluorescent dye known for its strong two-photon absorption at approximately 830 nm. This compound exhibits high quantum yield and photostability, making it suitable for a variety of biological imaging applications. It is commonly utilized in fluorescence microscopy, flow cytometry, and other techniques requiring sensitive detection of cellular and molecular interactions. -
Dye Agent
BTC-AM is a calcium indicator with a low affinity for calcium ions. It exhibits significant calcium-independent fluorescence across various excitation wavelengths, making it suitable for imaging applications. BTC-AM can be efficiently loaded into neurons where it undergoes rapid hydrolysis, facilitating real-time monitoring of cellular processes in neurobiology and other research applications involving calcium signaling. -
Fluorescent Probe
BOD-NH-NP is a fluorescent probe designed for the detection and imaging of endogenous nitric oxide through the endothelial nitric oxide synthase (eNOS) enzymatic pathway. This activatable probe offers high sensitivity and specificity, making it suitable for studying nitric oxide dynamics in biological systems. Researchers can utilize BOD-NH-NP to investigate various physiological and pathological processes where nitric oxide signaling plays a crucial role. -
Zn2+ Fluorescent Sensor
PMQA is an 8-aminoquinoline-based ratiometric fluorescent sensor designed for the detection of zinc ions (Zn2+). Upon interaction with Zn2+, PMQA exhibits a significant redshift in emission wavelength (85 nm), facilitating sensitive measurements. This cell membrane-permeable probe is suitable for real-time imaging of Zn2+ in living cells, making it valuable for studies in cellular signaling and zinc homeostasis. -
Fluorescent Probe
Nilotinib Acid is a fluorescent probe derivative of Nilotinib that is utilized for various biochemical applications. Its primary mechanism involves binding to specific molecular targets, enabling the visualization of cellular processes. This compound is particularly useful in research focused on cancer biology and drug development, where tracking the interaction of drugs with their molecular targets is crucial. -
Fluorescent Probe
Ponatinib Acid is a fluorescent probe that functions as a labeled chemical in biological research. Its structural analogue of Ponatinib features an alkyne group, enabling copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules. This property makes Ponatinib Acid invaluable for applications in click chemistry, facilitating studies in chemical biology and bioconjugation. -
Fluorescent DNA Stain
Hoechst 33342 analog trihydrochloride is a fluorescent DNA stain that preferentially binds to A/T-rich regions of double-stranded DNA. This compound is utilized in live cell imaging due to its ability to enhance fluorescence intensity when binding to nucleic acids, making it ideal for cellular labeling applications. The fluorescence signal can be further increased by adjusting the pH of the solution. Proper storage away from light is essential to maintain its effectiveness. -
Apoptotic Cell Fluorescent Dye
Apotracker Red is a fluorogenic dye designed to target apoptotic cells through its specific binding to phosphatidylserine (PtdSer) on the cell surface. Exhibiting excitation and emission wavelengths of 561 nm and 610 nm, respectively, Apotracker Red provides rapid and selective staining of apoptotic cells while leaving viable cells unmarked. This reagent is particularly useful for real-time detection of cancer cell death, facilitating insights into apoptosis-related research. -
Fluorescent Dye
5-JOE azide is a fluorescent dye that emits in the yellow region of the spectrum. It features an azide group that participates in Click Chemistry reactions with alkynes, BCN, or DBCO, resulting in a stable triazole linkage. This compound is valuable for various biological applications, including labeling and tracking of biomolecules in cellular and molecular biology studies. -
Fluorescent Dye
DMT-BH1 amidite is a prominent fluorescent dye characterized by its function as a dark quencher with a broad absorption profile, peaking in the green to yellow regions of the visible spectrum. This reagent is primarily utilized in the synthesis of dual-labeled oligonucleotide probes, particularly for quantitative PCR (qPCR) applications, incorporating the 5'-quencher DusQ 1. Its ability to facilitate Förster Resonance Energy Transfer (FRET) enhances multiplexing capabilities in various assay formats, making it an essential tool for advanced genetic research. -
Fluorescent Dye
SIMA phosphoramidite, 6-isomer, is a xanthene-based fluorescent dye exhibiting spectral properties comparable to HEX, combined with an enhanced quantum yield. This compound demonstrates superior stability during deprotection in alkaline environments, making it an ideal choice for applications in nucleic acid labeling and fluorescent assays. Its robust performance enables reliable detection in various research settings. -
Fluorescent Dye
BP Fluor 532 NHS ester is an amine-reactive fluorescent dye designed for labeling biomolecules, particularly proteins and antibodies, through primary amines. It exhibits bright yellow fluorescence and maintains stable emission across a wide pH range (4 to 10), making it suitable for diverse biological applications. The dye forms a stable covalent amide bond, with optimal labeling efficiency achieved at pH 7-9. BP Fluor 532 is compatible with frequency-doubled Nd:YAG laser excitation and is widely utilized in imaging techniques and flow cytometry to enhance signal stability. -
Fluorescent Dye
DMT-BH2 amidite is a black quencher dye designed for the synthesis of dual-labeled oligonucleotide probes with a 5'-quencher suitable for quantitative PCR (qPCR). This amidite effectively quenches fluorophores such as HEX, JOE, ROX, and Cyanine5, making it optimal for applications involving emissions in the orange and red regions of the spectrum. Its selective quenching properties enhance the sensitivity and specificity of nucleic acid detection assays. -
Fluorescein Dye
Fluorescein hydrazide (3,6-Dihydroxyxanthane) is a fluorescein dye that primarily targets reactive oxygen species (ROS) such as hydrogen peroxide (H2O2). This compound exhibits strong fluorescence properties, making it suitable for fluorophotometric assays in various biological studies. It is widely used in research applications focused on oxidative stress, cellular signaling, and ROS detection. -
Fluorescent Dye
2-Amino-5-methoxybenzamidoxime is a fluorescent dye utilized for the detection of various ketones, such as aromatic, hydroxyl, cyclic, and aliphatic ketones. This compound exhibits distinct fluorescence properties, with an excitation maximum at 389 nm and an emission maximum at 515 nm, making it suitable for applications in analytical chemistry and biochemistry for visualizing and quantifying ketone compounds. Its sensitivity and specificity make it an effective tool for researchers studying ketone-related biochemical processes. -
Fluorescent Dye
PSP is a two-photon fluorescent probe designed for the selective and sensitive detection of hydrogen sulfide (H2Sn) in live cells and tumor spheroids, with excitation and emission wavelengths of 440 nm and 640 nm, respectively. This reagent is particularly valuable in ferroptosis research, enabling real-time monitoring of reactive sulfur species within biological systems. Its high selectivity and sensitivity make PSP an essential tool for studying cellular pathways and mechanisms associated with oxidative stress and cell death. -
Potassium Fluorescent Indicator
Asante Potassium Green-1 (TMA) is a cell-impermeable fluorescent indicator designed to selectively detect potassium ions (K+) with an excitation wavelength of 525 nm and emission wavelength of 545 nm. This compound allows researchers to monitor intracellular potassium levels with high sensitivity and specificity, making it invaluable for studies involving ion transport, cellular signaling, and physiology. Its utility in real-time fluorescence imaging facilitates investigations into potassium's role in various biological processes and disease states. -
Potassium Fluorescent Indicator
Asante potassium green-1 AM is a cell-permeable potassium (K+) sensitive fluorescent indicator with an excitation/emission wavelength of 525/545 nm. This reagent enables the visualization and quantification of potassium ion fluctuations within live cells, making it suitable for studies in neurobiology, cardiac research, and cellular signaling. Its high sensitivity to K+ concentrations facilitates investigations into ion channel activity and cellular excitability, enhancing understanding of various physiological processes. -
Fluorescent Dye
Sulfo-QSY21-NHS is a fluorescent dye featuring an N-hydroxysuccinimide (NHS) moiety that readily reacts with amine groups (-NH2) present in proteins and other biomolecules, resulting in stable amide bond formation. This compound is commonly utilized in the synthesis of activity-based probes (ABPs), facilitating the study of enzyme activity and protein interactions in various biological research applications. Its robust fluorescent properties make it an ideal choice for high-sensitivity detection methods in biochemical assays. -
Azo Dye
Disperse Red 343 is an azo dye that primarily targets polyester fibers, functioning as a dyeing agent in textile applications. It exhibits strong color fastness properties, making it ideal for use in synthetic fabric coloration. Research applications may include studies on dye absorption, migration, and the environmental impact of azo dye usage in textile manufacturing processes. -
Azo Dye
Disperse Red 153 is an azo dye characterized by its vibrant red color and application in various industries. This compound demonstrates excellent compatibility with plastics and textiles, making it suitable for coloring applications in these materials. Additionally, its stability and non-volatile properties extend its utility to cosmetic formulations. -
K+ Fluorescent Indicator
IPG-2 AM is a membrane-permeable potassium (K+) fluorescent indicator. This reagent is designed to enable the detection and quantification of intracellular potassium ion concentrations in live cells through fluorescence microscopy. Its application is crucial in studies related to ion channel activity, cellular signaling, and neuronal function. -
GA Fluorescent Probe
AIE-GA is a fluorescent probe designed to target the Golgi apparatus, emitting fluorescence in the green channel with excitation at 405 nm and an emission range of 500-700 nm. This probe exhibits favorable binding affinity to cyclooxygenase-2 (COX-2), specifically interacting with its catalytic site. AIE-GA serves as a valuable tool for cellular imaging and studies involving the Golgi apparatus and COX-2, facilitating research in inflammation and related pathways. -
Fluorescent Probe
MIT-PZR is a mitochondria-targeted fluorescent probe designed for effective imaging applications. With low cytotoxicity, it is suitable for use in live-cell experiments and in vivo imaging studies. This probe exhibits excitation and emission maxima at 485 nm and 705 nm, respectively, enabling the visualization of mitochondrial activity and dynamics in real-time. -
Fluorescent Dye
Mito-CCY is a mitochondria-targeted fluorescent dye characterized by its near-infrared (NIR) absorption properties. This cryptocyanine probe exhibits high photothermal conversion efficiency and demonstrates good biological compatibility in vitro. Additionally, Mito-CCY induces photoinduced cytotoxicity in HeLa cells, making it a valuable tool for studies in mitochondrial dynamics and photothermal therapy applications. -
Fluorescent Dye
CellTracker Orange CMRA Dye is a fluorescent dye designed for cellular imaging and monitoring. It allows for the visualization of cellular movement and localization, providing insights into cell dynamics and behavior. This reagent is particularly useful in studies requiring tracking of live cells in a variety of biological contexts. -
Dye
7-Methoxycoumarin-3-carboxylic acid serves as a precursor for the synthesis of hydrophilic dye compounds. The resultant dye demonstrates a uniform distribution within cellular environments, making it an effective probe for assessing viscosity in the cytoplasm. This compound is valuable for various applications in cellular imaging and biophysical studies. -
pH Indicator Dye
m-Cresol purple is a pH indicator dye that exhibits halochromic properties, allowing for a clear visual transition in the neutral pH range. Its large cross-section enhances its sensitivity, making it an effective tool for monitoring pH changes in various biochemical assays. This compound is commonly utilized in laboratory settings for applications such as titrations, biological studies, and environmental analyses. -
Dye
Propyl Red is a versatile dye primarily used for biological staining. This compound facilitates the observation and analysis of cellular structures, enables biomolecule tracking, and assists in the evaluation of cell functions, making it valuable in both basic and clinical research applications. Additionally, Propyl Red is utilized for distinguishing cell types, detecting biomolecules, studying tissue pathology, and monitoring microorganisms. Beyond its biological uses, it finds applications in traditional textile dyeing and emerging technologies, including functional textiles and dye-sensitized solar cells. -
Calcium-binding Fluorescent Dye
Alizarin complexone is a calcium-binding fluorescent dye that specifically targets calcium crystals within mineralized areas of bone. This compound demonstrates notable antiviral activity, inhibiting reverse transcriptase activity in RAV-2, HIV-1, and RSV with IC50 values of 3.8 μg/mL, 45 μg/mL, and 100 μg/mL, respectively. In addition, Alizarin complexone has been shown to delay RSV-induced tumor induction in chicken models, making it valuable for research in virology and studies of calcium dynamics in mineralization processes. -
ACE-I Fluorescent Substrate
Abz-Gly-p-nitro-Phe-Pro-OH is a fluorescent substrate specific for angiotensin I converting enzyme (ACE-I), facilitating the study of enzyme kinetics and activity. The compound exhibits excitation at 355 nm and emission at 405 nm, making it suitable for high-sensitivity fluorescence assays. This substrate can be utilized in research applications focused on cardiovascular biology, hypertension, and related signaling pathways. -
GPR55 Fluorescent Ligand
Tocrifluor 1117 is a selective fluorescent ligand targeting the GPR55 receptor. This compound serves as a valuable tool in research for visualizing the cellular distribution of cannabinoid receptors, including GPR55, in live tissues. With excitation and emission maxima at 543 nm and 590 nm, respectively, Tocrifluor 1117 enhances the understanding of cannabinoid receptor localization and function in various biological contexts. -
Nitrite Dye
Calcium phosphorylcholine chloride (98%) is a key phospholipid component found in eukaryotic biofilms. This compound is present in both commensal and pathogenic bacteria associated with eukaryotes, contributing to their structural integrity. It demonstrates a notable range of immunomodulatory properties, making it valuable for research applications that explore immune responses and microbial interactions. -
fluorescent labeled LL-37, human (HY-P1222)
5-FAM-LL-37 is a fluorescently labeled analog of LL-37, a human antimicrobial peptide. This compound retains the biological activity of LL-37, enabling the study of its interactions and mechanisms of action in various biological systems. It is suitable for applications in immunology, infectious disease research, and cellular studies that require visualization of peptide localization and activity. -
Fluorescent Probe
Mz438 is a high-affinity fluorescent ligand targeting the chemokine receptor CXCR2. This small-molecule fluorescent probe is designed to visualize CXCR2 dynamics in live cells, making it a valuable tool for studying cellular signaling and migration in various biological systems. Its selectivity and binding properties facilitate research in inflammation and related diseases, enabling deeper insights into the role of CXCR2 in immune responses. -
Calcium-binding Fluorescent Dye
Alizarin complexone dihydrate is a calcium-binding fluorescent dye primarily used for visualizing mineralized areas in bone tissues. Its ability to bind calcium crystals enables effective staining, making it a valuable tool in bone research. Additionally, Alizarin complexone exhibits inhibitory effects on the reverse transcriptase activity of RAV-2, HIV-1, and RSV, with IC50 values of 3.8 μg/mL, 45 μg/mL, and 100 μg/mL, respectively, indicating its potential as an antiviral agent. Furthermore, it has been shown to delay RSV-induced tumor induction in avian models. -
TARMA Dye
DBCO-PEG4-TAMRA is a PEG-conjugated TAMRA dye featuring a dibenzocyclooctyne (DBCO) moiety, facilitating efficient Click Chemistry through strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules. This reagent is crucial for oligonucleotide labeling and is widely utilized in automated DNA sequencing applications. Its bioconjugation capabilities enhance the specificity and sensitivity of various research techniques, making it a valuable tool in molecular biology and biochemical studies. -
Reactive Dye
Sulfo-CY5-NHS ester potassium is a reactive dye that functions through the formation of stable amide bonds with primary amines on proteins and nucleic acids. This compound is primarily utilized for fluorescent labeling in biological research, enabling the visualization and tracking of biomolecules in various assays. Its high brightness and long-wavelength emission make it suitable for multiplexing applications and enhanced signal detection in imaging techniques. -
Fluorescence Dye
Acridine homodimer is a fluorescence dye that specifically targets DNA. It emits blue-green fluorescence upon binding, exhibiting a strong affinity for AT-rich regions of nucleic acids. This compound is particularly useful in chromosome banding and other applications involving nucleic acid visualization and quantification in research settings. -
Fluorescent Base Analogue
Tricyclic cytosine tC is a fluorescent base analogue designed to serve as a fluorescent probe in nucleic acid systems. It exhibits excitation at 385 nm and emits fluorescence at 505 nm. This compound is valuable for studying nucleic acid structures and dynamics, enabling researchers to investigate interactions and processes within genomic contexts. -
DNA/RNA Dye
Hydroxystilbamidine diisethionate is a DNA and RNA-binding dye that selectively inhibits cellular ribonucleases. This compound serves as a retrograde fluorescent tracer and is utilized in histochemical staining applications to visualize nucleic acids in various biological samples. Its dual function as a dye and an inhibitor makes it valuable for research in molecular biology and cellular assays. -
Fluorescent Dye
1-Aminoacridine is a fluorescent dye known for its bright emission properties. It interacts with DNA, exhibiting anti-infective and mutagenic activities, making it a valuable tool in molecular biology and genetic research. Its fluorescence facilitates the visualization of nucleic acids, aiding in studies of DNA structure and function. -
Acidic Dye
Acid Blue 129 is an acidic dye with a selective antagonistic effect on the P2Y receptor in guinea pig taenia coli, demonstrating its utility in biological research related to purinergic signaling. This compound does not interact with the P2X receptor in rat vas deferens, highlighting its specificity. Additionally, Acid Blue 129 is suitable for dyeing various materials, including cotton, wool, silk, nylon, paper, and leather, making it versatile for both scientific and industrial applications. -
ATP Fluorescent Analog
Formycin triphosphate is a fluorescent analog of ATP, designed to bind to enzyme active sites and exhibit enhanced fluorescence. It acts as an ATP-competitive inhibitor of chicken liver pyruvate carboxylase, enabling the study of ATP-dependent pathways. Additionally, Formycin triphosphate potentiates atrial natriuretic factor (ANF)-stimulated guanylate cyclase activity with an EC50 of approximately 90 μM and inhibits ATP-stimulated guanylate cyclase activity with an IC50 of around 100 μM, making it valuable for research in cellular signaling and metabolic regulation. -
Fluorescent Probe
BLT2 probe 1 is a fluorescent probe designed to target the BLT2 receptor, based on the synthetic BLT2 agonist CAY10583. This probe is a valuable tool for exploring the pharmacological properties of BLT2 receptor ligands. It is particularly relevant for research focused on diabetic wound healing and gastrointestinal lesions, facilitating studies across various assay systems.
