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Mz438

Catalog No.: A59803
Fluorescent Probe
Mz438 is a high-affinity fluorescent ligand targeting the chemokine receptor CXCR2. This small-molecule fluorescent probe is designed to visualize CXCR2 dynamics in live cells, making it a valuable tool for studying cellular signaling and migration in various biological systems. Its selectivity and binding properties facilitate research in inflammation and related diseases, enabling deeper insights into the role of CXCR2 in immune responses.
Mz438 3033041-20-9 Fluorescent Probe
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionMz438 is a high-affinity fluorescent ligand targeting the chemokine receptor CXCR2. This small-molecule fluorescent probe is designed to visualize CXCR2 dynamics in live cells, making it a valuable tool for studying cellular signaling and migration in various biological systems. Its selectivity and binding properties facilitate research in inflammation and related diseases, enabling deeper insights into the role of CXCR2 in immune responses.
Product Information
Catalog NumA59803
FormulaC57H63N9O12
Molecular Weight1066.16
CAS Number3033041-20-9
SMILESCC(C)([C@H](C1=CC=C(O1)C)NC2=C(C(C2=O)=O)NC(C=CC=C3C(NCC(N=N4)=CN4CCOCCOCCOCCNC(C5=CC=C(C([O-])=O)C(C(C(C=C6)=C(O7)C=C6N(C)C)=C8C7=C/C(C=C8)=[N+](C)/C)=C5)=O)=O)=C3O)C
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Autophagy Signaling > CXCR
Immunology & Inflammation > CXCR
GPCR/G Protein > CXCR
Dyes